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7C45
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BU of 7c45 by Molmil
The crystal structure of Trypanosoma brucei RNase D complex with RNA U12
Descriptor: CALCIUM ION, CCHC-type domain-containing protein, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Gao, Y.Q, Gan, J.H.
Deposit date:2020-05-15
Release date:2021-04-07
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
5UDZ
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BU of 5udz by Molmil
Human LIN28A in complex with let-7f-1 microRNA pre-element
Descriptor: Protein lin-28 homolog A, ZINC ION, let-7f-1 pre-element
Authors:Nam, Y, Wang, L, Sliz, P.
Deposit date:2016-12-29
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation.
Cell Rep, 18, 2017
7C42
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BU of 7c42 by Molmil
The crystal structure of Trypanosoma brucei RNase D
Descriptor: CCHC-type domain-containing protein, ZINC ION
Authors:Gao, Y.Q, Gan, J.H.
Deposit date:2020-05-14
Release date:2021-04-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
3TS2
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BU of 3ts2 by Molmil
Mouse Lin28A in complex with let-7g microRNA pre-element
Descriptor: Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*CP*UP*AP*UP*GP*AP*UP*AP*CP*CP*AP*CP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION
Authors:Nam, Y, Sliz, P.
Deposit date:2011-09-11
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Cell(Cambridge,Mass.), 147, 2011
7C4B
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BU of 7c4b by Molmil
The crystal structure of Trypanosoma brucei RNase D : UMP complex
Descriptor: CCHC-type domain-containing protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Gao, Y.Q, Gan, J.H.
Deposit date:2020-05-15
Release date:2021-04-07
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7C47
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BU of 7c47 by Molmil
The crystal structure of Trypanosoma brucei RNase D : CMP complex
Descriptor: CCHC-type domain-containing protein, CYTIDINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
Authors:Gao, Y.Q, Gan, J.H.
Deposit date:2020-05-15
Release date:2021-04-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7C4C
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BU of 7c4c by Molmil
The crystal structure of Trypanosoma brucei RNase D : GMP complex
Descriptor: CCHC-type domain-containing protein, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
Authors:Gao, Y.Q, Gan, J.H.
Deposit date:2020-05-15
Release date:2021-04-07
Method:X-RAY DIFFRACTION (2.265 Å)
Cite:Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
5W0M
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BU of 5w0m by Molmil
Structure of human TUT7 catalytic module (CM) in complex with U5 RNA
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
7C43
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BU of 7c43 by Molmil
The crystal structure of Trypanosoma brucei RNase D : AMP complex
Descriptor: ADENOSINE MONOPHOSPHATE, CCHC-type domain-containing protein, MANGANESE (II) ION, ...
Authors:Gao, Y.Q, Gan, J.H.
Deposit date:2020-05-14
Release date:2021-04-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
5W0O
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BU of 5w0o by Molmil
Structure of human TUT7 catalytic module (CM) in complex with dsRNA
Descriptor: Terminal uridylyltransferase 7, URIDINE 5'-TRIPHOSPHATE, double-stranded RNA
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0N
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BU of 5w0n by Molmil
Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
8E3I
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BU of 8e3i by Molmil
CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*CP*AP*UP*UP*AP*AP*AP*CP*AP*AP*C)-3'), ...
Authors:Gutierrez, P.A, Wei, J, Sun, Y, Tong, L.
Deposit date:2022-08-17
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
Rna, 28, 2022
5W0B
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BU of 5w0b by Molmil
Structure of human TUT7 catalytic module (CM)
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-30
Release date:2017-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.614 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
8E3Q
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BU of 8e3q by Molmil
CRYO-EM STRUCTURE OF the human MPSF
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, ZINC ION, ...
Authors:Gutierrez, P.A, Wei, J, Sun, Y, Tong, L.
Deposit date:2022-08-17
Release date:2023-01-18
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
Rna, 28, 2022
3NYB
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BU of 3nyb by Molmil
Structure and function of the polymerase core of TRAMP, a RNA surveillance complex
Descriptor: Poly(A) RNA polymerase protein 2, Protein AIR2, ZINC ION
Authors:Reinisch, K.M, Hamill, S.
Deposit date:2010-07-14
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7007 Å)
Cite:Structure and function of the polymerase core of TRAMP, a RNA surveillance complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
5O2U
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BU of 5o2u by Molmil
Llama VHH in complex with p24
Descriptor: Capsid protein p24, VHH 59H10
Authors:Caillat, C, Verrips, T, Weissenhorn, W.
Deposit date:2017-05-22
Release date:2017-06-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights.
ACS Infect Dis, 3, 2017
3TS0
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BU of 3ts0 by Molmil
Mouse Lin28A in complex with let-7f-1 microRNA pre-element
Descriptor: Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*AP*GP*UP*GP*AP*UP*UP*UP*UP*AP*CP*CP*CP*UP*GP*GP*AP*G)-3'), ZINC ION
Authors:Nam, Y, Sliz, P.
Deposit date:2011-09-11
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.763 Å)
Cite:Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Cell(Cambridge,Mass.), 147, 2011
3TRZ
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BU of 3trz by Molmil
Mouse Lin28A in complex with let-7d microRNA pre-element
Descriptor: Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*CP*AP*GP*GP*GP*AP*UP*UP*UP*UP*GP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION
Authors:Nam, Y, Sliz, P.
Deposit date:2011-09-11
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Cell(Cambridge,Mass.), 147, 2011
7VPX
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BU of 7vpx by Molmil
The cryo-EM structure of the human pre-A complex
Descriptor: 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-10-18
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism for Branch Site Recognition and Proofreading During Prespliceosome Assembly
To Be Published
6URG
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BU of 6urg by Molmil
Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ...
Authors:Sun, Y, Zhang, Y, Walz, T, Tong, L.
Deposit date:2019-10-23
Release date:2019-11-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020
7W5Z
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BU of 7w5z by Molmil
Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ...
Authors:Zhou, L, Maldonado, M, Padavannil, A, Letts, J.
Deposit date:2021-11-30
Release date:2022-04-06
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
8C9M
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BU of 8c9m by Molmil
HERV-K Gag immature lattice
Descriptor: Gag protein
Authors:Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P.
Deposit date:2023-01-23
Release date:2023-02-01
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular architecture and conservation of an immature human endogenous retrovirus.
Biorxiv, 2023
6DNH
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BU of 6dnh by Molmil
Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*C)-3'), ...
Authors:Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L.
Deposit date:2018-06-06
Release date:2018-06-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7Z52
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BU of 7z52 by Molmil
Human NEXT dimer - focused reconstruction of the single MTR4
Descriptor: Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ...
Authors:Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
Deposit date:2022-03-07
Release date:2022-06-22
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
6URO
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BU of 6uro by Molmil
Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, Cleavage stimulation factor subunit 3, ...
Authors:Sun, Y, Zhang, Y, Walz, T, Tong, L.
Deposit date:2019-10-23
Release date:2019-11-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020

 

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