1D0E
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CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN
Descriptor:REVERSE TRANSCRIPTASE (E.C.2.7.7.49)/DNA COMPLEX
Authors:Najmudin, S., Cote, M.L., Sun, D., Yohannan, S., Montano, S.P., Gu, J., Georgiadis, M.M.
Deposit date:1999-09-09
Release date:2000-04-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain
J.Mol.Biol., 296, 2000
1D1U
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USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS
Descriptor:PROTEIN (MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE)/DNA COMPLEX
Authors:Cote, M.L., Yohannan, S., Georgiadis, M.M.
Deposit date:1999-09-21
Release date:2000-04-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs.
Acta Crystallogr.,Sect.D, 56, 2000
1I6J
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CRYSTAL STRUCTURE OF A PSEUDO-16-MER DNA WITH STACKED GUANINES AND TWO G-A MISPAIRS COMPLEXED WITH THE N-TERMINAL FRAGMENT OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
Descriptor:REVERSE TRANSCRIPTASE (E.C. 2.7.7.49)/DNA Complex
Authors:Cote, M.L., Georgiadis, M.M.
Deposit date:2001-03-02
Release date:2001-09-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.
Acta Crystallogr.,Sect.D, 57, 2001
1MML
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MECHANISTIC IMPLICATIONS FROM THE STRUCTURE OF A CATALYTIC FRAGMENT OF MMLV REVERSE TRANSCRIPTASE
Descriptor:MMLV REVERSE TRANSCRIPTASE
Authors:Georgiadis, M.M., Jessen, S.M., Ogata, C.M., Telesnitsky, A., Goff, S.P., Hendrickson, W.A.
Deposit date:1995-07-18
Release date:1995-10-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase.
Structure, 3, 1995
1N4L
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A DNA ANALOGUE OF THE POLYPURINE TRACT OF HIV-1
Descriptor:Reverse Transcriptase (E.C.2.7.7.49)/DNA complex
Authors:Cote', M.L., Pflomm, M., Georgiadis, M.M.
Deposit date:2002-10-31
Release date:2003-06-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Staying Straight with A-tracts: A DNA Analog of the HIV-1 Polypurine Tract
J.Mol.Biol., 330, 2003
1NND
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ARGININE 116 IS ESSENTIAL FOR NUCLEIC ACID RECOGNITION BY THE FINGERS DOMAIN OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
Descriptor:Reverse Transcriptase (E.C.2.7.7.49)
Authors:Crowther, R.L., Remeta, D.P., Minetti, C.A., Das, D., Montano, S.P., Georgiadis, M.M.
Deposit date:2003-01-13
Release date:2004-01-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase
Proteins, 57, 2004
1QAI
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CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN
Descriptor:REVERSE TRANSCRIPTASE (E.C.2.7.7.49)/DNA COMPLEX
Authors:Najmudin, S., Cote, M., Sun, D., Yohannan, S., Montano, S.P., Gu, J., Georgiadis, M.M.
Deposit date:1999-03-12
Release date:2000-03-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
J.Mol.Biol., 296, 2000
1QAJ
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CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN
Descriptor:REVERSE TRANSCRIPTASE (E.C.2.7.7.49)/DNA COMPLEX
Authors:Najmudin, S., Cote, M., Sun, D., Yohannan, S., Montano, S.P., Gu, J., Georgiadis, M.M.
Deposit date:1999-03-18
Release date:2000-04-02
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
J.Mol.Biol., 296, 2000
1ZTT
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NETROPSIN BOUND TO D(CTTAATTCGAATTAAG) IN COMPLEX WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex, NETROPSIN
Authors:Goodwin, K.D., Long, E.C., Georgiadis, M.M.
Deposit date:2005-05-27
Release date:2005-08-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
1ZTW
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D(CTTAATTCGAATTAAG) COMPLEXED WITH MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE CATALYTIC FRAGMENT
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex
Authors:Goodwin, K.D., Long, E.C., Georgiadis, M.M.
Deposit date:2005-05-27
Release date:2005-08-30
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A host-guest approach for determining drug-DNA interactions: an example using netropsin.
Nucleic Acids Res., 33, 2005
2FJV
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RT29 BOUND TO D(CTTAATTCGAATTAAG) IN COMPLEX WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse Transcriptase (E.C.2.7.7.49/DNA Complex
Authors:Goodwin, K.D., Georgiadis, M.M.
Deposit date:2006-01-03
Release date:2006-06-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FJW
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D(CTTGAATGCATTCAAG) IN COMPLEX WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse Transcriptase (E.C.2.7.7.49/DNA Complex
Authors:Goodwin, K.D., Georgiadis, M.M
Deposit date:2006-01-03
Release date:2006-06-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FJX
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RT29 BOUND TO D(CTTGAATGCATTCAAG) IN COMPLEX WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse Transcriptase (E.C.2.7.7.49/DNA Complex
Authors:Goodwin, K.D., Georgiadis, M.M.
Deposit date:2006-01-03
Release date:2006-06-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FVP
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A STRUCTURAL STUDY OF THE CA DINUCLEOTIDE STEP IN THE INTEGRASE PROCESSING SITE OF MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex
Authors:Montano, S.P., Cote, M.L., Roth, M.J., Georgiadis, M.M.
Deposit date:2006-01-31
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVQ
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A STRUCTURAL STUDY OF THE CA DINUCLEOTIDE STEP IN THE INTEGRASE PROCESSING SITE OF MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex
Authors:Montano, S.P., Cote, M.L., Roth, M.J., Georgiadis, M.M.
Deposit date:2006-01-31
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVR
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A STRUCTURAL STUDY OF THE CA DINUCLEOTIDE STEP IN THE INTEGRASE PROCESSING SITE OF MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase (EC 2.7.7.49)/DNA Complex
Authors:Montano, S.P., Cote, M.L., Roth, M.J., Georgiadis, M.M.
Deposit date:2006-01-31
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVS
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A STRUCTURAL STUDY OF THE CA DINUCLEOTIDE STEP IN THE INTEGRASE PROCESSING SITE OF MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase (EC 2.7.7.49)/DNA Complex
Authors:Montano, S.P., Cote, M.L., Roth, M.J., Georgiadis, M.M.
Deposit date:2006-01-31
Release date:2006-12-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2R2R
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D(ATTAGTTATAACTAAT) COMPLEXED WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex
Authors:Goodwin, K.D., Lewis, M.A., Long, E.C., Georgiadis, M.M.
Deposit date:2007-08-27
Release date:2008-07-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2S
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CO(III)BLEOMYCINB2 BOUND TO D(ATTAGTTATAACTAAT) COMPLEXED WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex, Bleomycin B2
Authors:Goodwin, K.D., Lewis, M.A., Long, E.C., Georgiadis, M.M.
Deposit date:2007-08-27
Release date:2008-07-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2T
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D(ATTTAGTTAACTAAAT) COMPLEXED WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse transcriptase (E.C. 2.7.7.49)/DNA Complex
Authors:Goodwin, K.D., Lewis, M.A., Long, E.C., Georgiadis, M.M.
Deposit date:2007-08-27
Release date:2008-07-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R2U
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CO(III)BLEOMYCINB2 BITHIAZOLE/C-TERMINAL TAIL DOMAIN BOUND TO D(ATTTAGTTAACTAAAT) COMPLEXED WITH MMLV RT CATALYTIC FRAGMENT
Descriptor:Reverse transcriptase (E.C.2.7.7.49)/DNA Complex, BITHIAZOLE
Authors:Goodwin, K.D., Lewis, M.A., Long, E.C., Georgiadis, M.M.
Deposit date:2007-08-27
Release date:2008-07-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3FSI
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CRYSTAL STRUCTURE OF A TRYPANOCIDAL 4,4'-BIS(IMIDAZOLINYLAMINO)DIPHENYLAMINE BOUND TO DNA
Descriptor:Reverse transcriptase domain (E.C.2.7.7.49)
Authors:Glass, L.S., Georgiadis, M.M., Goodwin, K.D.
Deposit date:2009-01-09
Release date:2009-05-19
Modification date:2014-12-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA.
Biochemistry, 48, 2009
4M94
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D(ATCCGTTATAACGGAT) COMPLEXED WITH MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE CATALYTIC FRAGMENT
Descriptor:Gag-Pol polyprotein (E.C.3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.4)
Authors:Singh, I.
Deposit date:2013-08-14
Release date:2014-03-12
Modification date:2014-04-02
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
Acta Crystallogr.,Sect.D, 70, 2014
4M95
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D(ATCCGTTATAACGGAT)COMPLEXED WITH MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE CATALYTIC FRAGMENT
Descriptor:Gag-Pol polyprotein (E.C.3.4.23.-, 2.7.7.49, 2.7.7.7, 3.1.26.4)
Authors:Singh, I.
Deposit date:2013-08-14
Release date:2014-03-12
Modification date:2014-04-02
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
Acta Crystallogr.,Sect.D, 70, 2014
4OL8
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TY3 REVERSE TRANSCRIPTASE BOUND TO DNA/RNA
Descriptor:Reverse transcriptase/ribonuclease H (E.C.2.7.7.49, 2.7.7.7, 3.1.26.4)
Authors:Nowak, E., Miller, J.T., Bona, M.K., Studnicka, J., Szczepanowski, R.H., Jurkowski, J., Le Grice, S.F.J., Nowotny, M.
Deposit date:2014-01-23
Release date:2014-03-05
Modification date:2014-04-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
Nat.Struct.Mol.Biol., 21, 2014
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