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1PB5
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1pb5
NMR STRUCTURE OF A PROTOTYPE LNR MODULE FROM HUMAN NOTCH1
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Vardar, D., North, C.L., Sanchez-Irizarry, C., Aster, J.C., Blacklow, S.C.
Deposit date:2003-05-14
Release date:2003-06-17
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Structure of a Prototype Lin12-Notch Repeat Module from Human Notch1
Biochemistry, 42, 2003
2OO4
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2oo4
STRUCTURE OF LNR-HD (NEGATIVE REGULATORY REGION) FROM HUMAN NOTCH 2
Descriptor:Neurogenic locus notch homolog protein 2
Authors:Gordon, W.R., Vardar-Ulu, D., Histen, G., Sanchez-Irizarry, C., Aster, J.C., Blacklow, S.C.
Deposit date:2007-01-25
Release date:2007-04-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural basis for autoinhibition of Notch
Nat.Struct.Mol.Biol., 14, 2007
3ETO
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3eto
2 ANGSTROM XRAY STRUCTURE OF THE NOTCH1 NEGATIVE REGULATORY REGION (NRR)
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Gordon, W.R., Blacklow, S.C.
Deposit date:2008-10-08
Release date:2008-12-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Blood, 113, 2009
3I08
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3i08
CRYSTAL STRUCTURE OF THE S1-CLEAVED NOTCH1 NEGATIVE REGULATORY REGION (NRR)
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Gordon, W.R., Blacklow, S.C.
Deposit date:2009-06-24
Release date:2009-09-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2.
Plos One, 4, 2009
3L95
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3l95
CRYSTAL STRUCTURE OF THE HUMAN NOTCH1 NEGATIVE REGULATORY REGION (NRR) BOUND TO THE FAB FRAGMENT OF AN ANTAGONIST ANTIBODY
Descriptor:anti-NRR1 fab fragment light chain, anti-NRR1 fab fragment heavy chain , Neurogenic locus notchhomolog protein 1
Authors:Hymowitz, S.G., de Leon, G.P.
Deposit date:2010-01-04
Release date:2010-03-09
Modification date:2013-09-25
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Therapeutic antibody targeting of individual Notch receptors.
Nature, 464, 2010
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103354
entries available on 2014-09-17
00:00 UTC / 09:00 JST