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1B9G
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1b9g
INSULIN-LIKE-GROWTH-FACTOR-1
Descriptor:GROWTH-FACTOR IGF-1
Authors:De Wolf, E., Gill, R., Geddes, S., Pitts, J., Wollmer, A., Grotzinger, J.
Deposit date:1999-02-11
Release date:1999-02-23
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of a mini IGF-1.
Protein Sci., 5, 1996
1BOM
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1bom
THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN
Descriptor:BOMBYXIN-II (NMR, MINIMIZED AVERAGE STRUCTURE)
Authors:Nagata, K., Hatanaka, H., Kohda, D., Inagaki, F.
Deposit date:1994-07-21
Release date:1994-11-01
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
1BON
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1bon
THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN
Descriptor:BOMBYXIN-II (NMR, 10 STRUCTURES)
Authors:Nagata, K., Hatanaka, H., Kohda, D., Inagaki, F., Structural Proteomics in Europe (SPINE)
Deposit date:1994-07-21
Release date:1995-01-26
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
1BQT
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1bqt
THREE-DIMENSIONAL STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR-I (IGF-I) DETERMINED BY 1H-NMR AND DISTANCE GEOMETRY, 6 STRUCTURES
Descriptor:INSULIN-LIKE GROWTH FACTOR-I
Authors:Sato, A., Nishimura, S., Ohkubo, T., Kyogoku, Y., Koyama, S., Kobayashi, M., Yasuda, T., Kobayashi, Y.
Deposit date:1998-08-18
Release date:1999-05-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry.
Int.J.Pept.Protein Res., 41, 1993
1EFE
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1efe
AN ACTIVE MINI-PROINSULIN, M2PI
Descriptor:AN ACTIVE MINI-PROINSULIN, M2PI
Authors:Cho, Y., Chang, S.G., Choi, K.D., Shin, H., Ahn, B., Kim, K.S.
Deposit date:2000-02-08
Release date:2000-03-17
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity
J.Biochem.Mol.Biol., 33, 2000
1GZR
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1gzr
HUMAN INSULIN-LIKE GROWTH FACTOR; ESRF DATA
Descriptor:INSULIN-LIKE GROWTH FACTOR I
Authors:Brzozowski, A.M., Dodson, E.J., Dodson, G.G., Murshudov, G., Verma, C., Turkenburg, J.P., De Bree, F.M., Dauter, Z.
Deposit date:2002-05-28
Release date:2002-07-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1GZY
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1gzy
HUMAN INSULIN-LIKE GROWTH FACTOR; IN-HOUSE DATA
Descriptor:INSULIN-LIKE GROWTH FACTOR I
Authors:Brzozowski, A.M., Dodson, E.J., Dodson, G.G., Murshudov, G., Verma, C., Turkenburg, J.P., De Bree, F.M., Dauter, Z.
Deposit date:2002-06-10
Release date:2002-07-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1GZZ
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1gzz
HUMAN INSULIN-LIKE GROWTH FACTOR; HAMBURG DATA
Descriptor:INSULIN-LIKE GROWTH FACTOR I
Authors:Brzozowski, A.M., Dodson, E.J., Dodson, G.G., Murshudov, G., Verma, C., Turkenburg, J.P., De Bree, F.M., Dauter, Z.
Deposit date:2002-06-10
Release date:2002-07-25
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1H02
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1h02
HUMAN INSULIN-LIKE GROWTH FACTOR; SRS DARESBURY DATA
Descriptor:INSULIN-LIKE GROWTH FACTOR I
Authors:Brzozowski, A.M., Dodson, E.J., Dodson, G.G., Murshudov, G., Verma, C., Turkenburg, J.P., De Bree, F.M., Dauter, Z.
Deposit date:2002-06-11
Release date:2002-07-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
1HO0
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1ho0
NEW B-CHAIN MUTANT OF BOVINE INSULIN
Descriptor:INSULIN
Authors:Dupradeau, F.Y., Richard, T., Le Flem, G., Oulyadi, H., Prigent, Y., Monti, J.P.
Deposit date:2000-12-08
Release date:2000-12-20
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:A new B-chain mutant of insulin: comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structure
J.Pept.Res., 60, 2002
1IGL
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1igl
SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS
Descriptor:INSULIN-LIKE GROWTH FACTOR II (IGF-II, IGF-2) (NMR, 20 STRUCTURES)
Authors:Torres, A.M., Forbes, B.E., Aplin, S.E., Wallace, J.C., Francis, G.L., Norton, R.S.
Deposit date:1994-12-29
Release date:1995-02-14
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions.
J.Mol.Biol., 248, 1995
1IMX
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1imx
1.8 ANGSTROM CRYSTAL STRUCTURE OF IGF-1
Descriptor:Insulin-like Growth Factor-1
Authors:Vajdos, F.F., Ultsch, M., Schaffer, M.L., Deshayes, K.D., Liu, J., Skelton, N.J., de Vos, A.M.
Deposit date:2001-05-11
Release date:2001-09-05
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
Biochemistry, 40, 2001
1PMX
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1pmx
INSULIN-LIKE GROWTH FACTOR-I BOUND TO A PHAGE-DERIVED PEPTIDE
Descriptor:INSULIN-LIKE GROWTH FACTOR IB/IGF-1 ANTAGONIST F1-1
Authors:Skelton, N.J.
Deposit date:2003-06-11
Release date:2003-10-21
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Complex with a Phage Display-Derived Peptide Provides Insight into the Function of Insulin-like Growth Factor I
Biochemistry, 42, 2003
1TGR
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1tgr
CRYSTAL STRUCTURE OF MINI-IGF-1(2)
Descriptor:Insulin-like growth factor IA
Authors:Liang, D.C., Yun, C.H., Chang, W.R.
Deposit date:2004-05-29
Release date:2004-12-28
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:1.42A crystal structure of mini-IGF-1(2): an analysis of the disulfide isomerization property and receptor binding property of IGF-1 based on the three-dimensional structure
Biochem.Biophys.Res.Commun., 326, 2004
1VKT
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1vkt
HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES
Descriptor:INSULIN
Authors:Hua, Q.X., Hu, S.Q., Frank, B.H., Jia, W.H., Chu, Y.C., Wang, S.H., Burke, G.T., Katsoyannis, P.G., Weiss, M.A.
Deposit date:1996-10-14
Release date:1997-04-01
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264, 1996
1ZEI
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1zei
CROSS-LINKED B28 ASP INSULIN
Descriptor:INSULIN, M-CRESOL
Authors:Whittingham, J.L., Edwards, E.J., Antson, A.A., Clarkson, J.M., Dodson, G.G.
Deposit date:1998-07-14
Release date:1999-02-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
2GF1
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2gf1
SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY
Descriptor:INSULIN-LIKE GROWTH FACTOR (NMR, MINIMUM AVERAGE STRUCTURE)
Authors:Cooke, R.M., Harvey, T.S., Campbell, I.D.
Deposit date:1991-01-23
Release date:1993-04-15
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
Biochemistry, 30, 1991
2JZQ
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2jzq
DESIGN OF AN ACTIVE ULTRA-STABLE SINGLE-CHAIN INSULIN ANALOG 20 STRUCTURES
Descriptor:Insulin
Authors:Hua, Q.X., Nakarawa, S., Jia, W.H., Huang, K., Philips, N.F., Hu, S.Q., Weiss, M.A.
Deposit date:2008-01-11
Release date:2008-02-26
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications.
J.Biol.Chem., 283, 2008
2KQP
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2kqp
NMR STRUCTURE OF PROINSULIN
Descriptor:Insulin
Authors:Yang, Y., Hua, Q.X., Mackin, R.B., Weiss, M.A.
Deposit date:2009-11-12
Release date:2010-01-26
Modification date:2010-05-05
Method:SOLUTION NMR
Cite:Solution structure of proinsulin: connecting domain flexibility and prohormone processing.
J.Biol.Chem., 285, 2010
2LWZ
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2lwz
NMR STRUCTURES OF SINGLE-CHAIN INSULIN
Descriptor:SINGLE-CHAIN INSULIN
Authors:Weiss, M.A., Yang, Y.
Deposit date:2012-08-09
Release date:2013-08-28
Method:SOLUTION NMR
Cite:Dynamic repair of an amyloidogenic protein: Insulin fibrillation is blocked by tethering a nascent alpha-helix
To be Published
2W44
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2w44
STRUCTURE DELTAA1-A4 INSULIN
Descriptor:INSULIN
Authors:Thorsoee, K.S., Schlein, M., Brandt, J., Schluckebier, G., Naver, H.
Deposit date:2008-11-21
Release date:2009-12-22
Modification date:2013-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform.
Biochemistry, 49, 2010
2WFU
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2wfu
CRYSTAL STRUCTURE OF DILP5 VARIANT DB
Descriptor:PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN
Authors:Kulahin, N., Schluckebier, G., Sajid, W., De Meyts, P.
Deposit date:2009-04-15
Release date:2010-05-26
Modification date:2012-04-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation.
J.Biol.Chem., 286, 2011
2WFV
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2wfv
CRYSTAL STRUCTURE OF DILP5 VARIANT C4
Descriptor:PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN
Authors:Kulahin, N., Schluckebier, G., Sajid, W., De Meyts, P.
Deposit date:2009-04-15
Release date:2010-05-26
Modification date:2012-04-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation.
J.Biol.Chem., 286, 2011
3GF1
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3gf1
SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY
Descriptor:INSULIN-LIKE GROWTH FACTOR (NMR, 10 STRUCTURES)
Authors:Cooke, R.M., Harvey, T.S., Campbell, I.D.
Deposit date:1991-01-24
Release date:1993-04-15
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
Biochemistry, 30, 1991
3LRI
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3lri
SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF LONG-[ARG(3)]INSULIN-LIKE GROWTH FACTOR-I
Descriptor:INSULIN-LIKE GROWTH FACTOR-1 IGF-I
Authors:Laajoki, L.G., Francis, G.L., Wallace, J.C., Carver, J.A., Keniry, M.A.
Deposit date:1999-04-13
Release date:2000-05-23
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I
J.Biol.Chem., 275, 2000
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