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4FQQ
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4fqq
CRYSTAL STRUCTURE OF GERMLINE ANTIBODY PGT121-GL FAB
Descriptor:Fab light chain, Fab heavy chain
Authors:Scharf, L., Bjorkman, P.J.
Deposit date:2012-06-25
Release date:2012-11-14
Modification date:2012-12-12
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
1H5B
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1h5b
T CELL RECEPTOR VALPHA11 (AV11S5) DOMAIN
Descriptor:MURINE T CELL RECEPTOR (TCR) VALPHA DOMAIN
Authors:Machius, M., Cianga, P., Deisenhofer, J., Ward, E.S.
Deposit date:2001-05-21
Release date:2001-06-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of a T Cell Receptor Valpha11 (Av11S5) Domain: New Canonical Forms for the First and Second Complementarity Determining Regions
J.Mol.Biol., 310, 2001
3B9K
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3b9k
CRYSTAL STRUCTURE OF CD8ALPHA-BETA IN COMPLEX WITH YTS 156.7 FAB
Descriptor:Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB
Authors:Shore, D., Wilson, I.A.
Deposit date:2007-11-05
Release date:2008-11-11
Modification date:2013-09-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I
J.Mol.Biol., 384, 2008
3ULU
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3ulu
STRUCTURE OF QUATERNARY COMPLEX OF HUMAN TLR3ECD WITH THREE FABS (FORM1)
Descriptor:Toll-like receptor 3, Fab15 light chain, Fab15 heavy chain, Fab12 light chain, Fab12 heavy chain, Fab1068 light chain, Fab1068 heavy chain
Authors:Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A.
Deposit date:2011-11-11
Release date:2012-05-23
Modification date:2012-07-25
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
3ULV
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3ulv
STRUCTURE OF QUATERNARY COMPLEX OF HUMAN TLR3ECD WITH THREE FABS (FORM2)
Descriptor:Toll-like receptor 3, Fab15 light chain, Fab15 heavy chain, Fab12 light chain, Fab12 heavy chain, Fab1068 light chain, Fab1068 heavy chain
Authors:Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A.
Deposit date:2011-11-11
Release date:2012-05-23
Modification date:2012-07-25
Method:X-RAY DIFFRACTION (3.522 Å)
Cite:Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
15C8
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15c8
CATALYTIC ANTIBODY 5C8, FREE FAB
Descriptor:IGG 5C8
Authors:Gruber, K., Wilson, I.A.
Deposit date:1998-03-18
Release date:1999-03-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ligand-Induced Conformational Changes in a Catalytic Antibody: Comparison of the Bound and Unbound Structure of Fab 5C8
To be Published
1CIC
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1cic
IDIOTOPE-ANTI-IDIOTOPE FAB-FAB COMPLEX; D1.3-E225
Descriptor:IG HEAVY CHAIN V REGIONS
Authors:Bentley, G.A.
Deposit date:1999-03-31
Release date:1999-04-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of an idiotope-anti-idiotope complex.
Nature, 348, 1990
1G9M
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1g9m
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, CD4, ANTIBODY 17B-LIGHT AND HEAVY CHAIN COMPLEX
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-24
Release date:2000-12-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1G9N
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1g9n
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, CD4, ANTIBODY 17B-LIGHT AND HEAVY CHAIN COMPLEX
Authors:Kwong, P.D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:2000-11-25
Release date:2000-12-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
1GC1
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1gc1
HIV-1 GP120 CORE COMPLEXED WITH CD4 AND A NEUTRALIZING HUMAN ANTIBODY
Descriptor:ENVELOPE PROTEIN GP120, CD4, ANTIBODY 17B
Authors:Kwong, P.D., Wyatt, R., Robinson, J., Sweet, R.W., Sodroski, J., Hendrickson, W.A.
Deposit date:1998-06-15
Release date:1998-07-08
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Nature, 393, 1998
1IAI
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1iai
IDIOTYPE-ANTI-IDIOTYPE FAB COMPLEX
Descriptor:IDIOTYPIC FAB 730.1.4 (IGG1) OF VIRUS NEUTRALIZING ANTIBODY, ANTI-IDIOTYPIC FAB 409.5.3 (IGG2A)
Authors:Ban, N., Escobar, C., Garcia, R., Hasel, K., Day, J., Greenwood, A., McPherson, A.
Deposit date:1993-12-28
Release date:1996-03-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an idiotype-anti-idiotype Fab complex.
Proc.Natl.Acad.Sci.USA, 91, 1994
1KB5
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1kb5
MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX
Descriptor:KB5-C20 T-CELL ANTIGEN RECEPTOR, ANTIBODY DESIRE-1
Authors:Housset, D., Mazza, G., Gregoire, C., Piras, C., Malissen, B., Fontecilla-Camps, J.C.
Deposit date:1997-04-06
Release date:1998-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain.
EMBO J., 16, 1997
1QFW
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1qfw
TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT
Descriptor:GONADOTROPIN ALPHA SUBUNIT, GONADOTROPHIN BETA SUBUNIT, ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI BETA SUBUNIT) (LIGHT CHAIN), ANTIBODY (ANTI BETA SUBUNIT) (HEAVY CHAIN)
Authors:Tegoni, M., Spinelli, S., Cambillau, C.
Deposit date:1999-04-15
Release date:2000-04-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
1RZJ
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1rzj
HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEINS GP120 AND CD4/ANTIBODY 17B-LIGHT AND HEAVY CHAINS COMPLEX
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZK
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1rzk
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEINS GP120 AND CD4/ANTIBODY 17B-LIGHT AND HEAVY CHAINS COMPLEX
Authors:Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
25C8
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25c8
CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX
Descriptor:IGG 5C8, N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION
Authors:Gruber, K., Wilson, I.A.
Deposit date:1998-03-18
Release date:1999-03-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry, 38, 1999
2ARJ
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2arj
CD8ALPHA-ALPHA IN COMPLEX WITH YTS 105.18 FAB
Descriptor:YTS 105.18 antigen binding region Light chain, YTS 105.18 antigen binding region Heavy chain, T-cell surface glycoprotein CD8 alpha chain
Authors:Shore, D.A., Teyton, L., Dwek, R.A., Rudd, P.M., Wilson, I.A.
Deposit date:2005-08-19
Release date:2006-05-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
J.Mol.Biol., 358, 2006
2ATP
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2atp
CRYSTAL STRUCTURE OF A CD8AB HETERODIMER
Descriptor:T-cell surface glycoprotein CD8 alpha chain, artifact linker, T-cell surface glycoprotein CD8 beta chain
Authors:Chang, H.C., Tan, K., Ouyang, J., Parisini, E., Liu, J.H., Le, Y., Wang, X., Reinherz, E.L., Wang, J.H.
Deposit date:2005-08-25
Release date:2005-12-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer.
Immunity, 23, 2005
2B4C
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2b4c
CRYSTAL STRUCTURE OF HIV-1 JR-FL GP120 CORE PROTEIN CONTAINING THE THIRD VARIABLE REGION (V3) COMPLEXED WITH CD4 AND THE X5 ANTIBODY
Descriptor:envelope glycoprotein, T-cell surface glycoprotein CD4, anti-HIV-1 gp120 immunoglobulin X5 light chain, anti-HIV-1 gp120 immunoglobulin X5 heavy chain
Authors:Huang, C., Tang, M., Zhang, M.Y., Majeed, S., Montabana, E., Stanfield, R.L., Dimitrov, D.S., Korber, B., Sodroski, J., Wilson, I.A., Wyatt, R., Kwong, P.D.
Deposit date:2005-09-23
Release date:2005-11-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a V3-containing HIV-1 gp120 core.
Science, 310, 2005
2NXY
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2nxy
HIV-1 GP120 ENVELOPE GLYCOPROTEIN(S334A) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NXZ
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2nxz
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (T257S, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY0
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2ny0
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (M95W, W96C, T257S, V275C, S334A, S375W, A433M) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY1
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2ny1
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (I109C, T257S, S334A, S375W, Q428C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120 , T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN , ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X, Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY2
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2ny2
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (T123C, T257S, S334A, S375W, G431C) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
2NY3
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2ny3
HIV-1 GP120 ENVELOPE GLYCOPROTEIN (K231C, T257S, E267C, S334A, S375W) COMPLEXED WITH CD4 AND ANTIBODY 17B
Descriptor:ENVELOPE GLYCOPROTEIN GP120, T-cell surface glycoprotein CD4, ANTIBODY 17B, LIGHT CHAIN, ANTIBODY 17B, HEAVY CHAIN
Authors:Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
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