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8HKP
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BU of 8hkp by Molmil
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry)
Descriptor: Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-11-27
Release date:2023-03-22
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
8GN8
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BU of 8gn8 by Molmil
structure of human connexin 40.1 pentameric hemichannel by cryoEM
Descriptor: Gap junction delta-4 protein
Authors:Zhang, H, Wang, D.P.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:structure of human connexin 40.1 intercellular gap junction channel by cryoEM
To Be Published
8GNB
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BU of 8gnb by Molmil
structure of human connexin 40.1 side-by-side decamer channel by cryoEM
Descriptor: Gap junction delta-4 protein
Authors:Zhang, H, Wang, D.P.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:structure of human connexin 40.1 side-by-side decamer channel by cryoEM
To Be Published
8GN7
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BU of 8gn7 by Molmil
structure of human connexin 40.1 intercellular gap junction channel by cryoEM
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Gap junction delta-4 protein, ...
Authors:Zhang, H, Wang, D.P.
Deposit date:2022-08-23
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:structure of human connexin 40.1 intercellular gap junction channel by cryoEM
To Be Published
7ZXQ
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BU of 7zxq by Molmil
cryo-EM structure of Connexin 32 R22G mutation hemi channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structures of connexin 32 channels suggest a link between hemichannel gating and disease-associated mutations
To Be Published
7ZXT
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BU of 7zxt by Molmil
cryo-EM structure of Connexin 32 W3S mutation hemi channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of connexin 32 channels suggest a link between hemichannel gating and disease-associated mutations
To Be Published
7ZXP
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BU of 7zxp by Molmil
cryo-EM structure of Connexin 32 R22G mutation gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Structures of connexin 32 channels suggest a link between hemichannel gating and disease-associated mutations
To Be Published
7ZXM
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BU of 7zxm by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Structures of connexin 32 channels suggest a link between hemichannel gating and disease-associated mutations
To Be Published
7ZXN
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BU of 7zxn by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: CHOLESTEROL, Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structures of connexin 32 channels suggest a link between hemichannel gating and disease-associated mutations
To Be Published
7ZXO
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BU of 7zxo by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of connexin 32 channels suggest a link between hemichannel gating and disease-associated mutations
To Be Published
7XQB
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BU of 7xqb by Molmil
Structure of connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs at pH ~8.0
Descriptor: CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-02-01
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQH
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BU of 7xqh by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN-TM1i conformation)
Descriptor: C-terminal deletion mutant of gap junction alpha-1 protein (Cx43-M257)
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQG
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BU of 7xqg by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN conformation)
Descriptor: CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQJ
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BU of 7xqj by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (PLN conformation)
Descriptor: Gap junction alpha-1 protein
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQI
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BU of 7xqi by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (FIN conformation)
Descriptor: Gap junction alpha-1 protein
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQ9
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BU of 7xq9 by Molmil
Structure of connexin43/Cx43/GJA1 gap junction intercellular channel in GDN detergents at pH ~8.0
Descriptor: Gap junction alpha-1 protein
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQD
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BU of 7xqd by Molmil
Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs (C1 symmetry)
Descriptor: CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-02-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQF
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BU of 7xqf by Molmil
Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE/CHS nanodiscs
Descriptor: CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-02-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XNV
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BU of 7xnv by Molmil
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-29
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XNH
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BU of 7xnh by Molmil
Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-28
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XL8
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BU of 7xl8 by Molmil
Human Cx36/GJD2 (N-terminal deletion mutant) gap junction channel in soybean lipids (D6 symmetry)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-21
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XKT
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BU of 7xkt by Molmil
Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H.
Deposit date:2022-04-20
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XKI
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BU of 7xki by Molmil
Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry)
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction delta-2 protein,Soluble cytochrome b562
Authors:Cho, H.J, Lee, S.N, Jeong, H, Ryu, B, Lee, H.J, Woo, J.S, Lee, H.H.
Deposit date:2022-04-19
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7XKK
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BU of 7xkk by Molmil
Human Cx36/GJD2 gap junction channel in detergents
Descriptor: Gap junction delta-2 protein
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-04-19
Release date:2023-04-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
7Z22
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BU of 7z22 by Molmil
Connexin43 gap junction channel structure in nanodisc
Descriptor: Gap junction alpha-1 protein
Authors:Qi, C, Korkhov, M.V.
Deposit date:2022-02-25
Release date:2023-03-08
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structure of the connexin-43 gap junction channel in a putative closed state.
Elife, 12, 2023

 

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