1CX4
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CRYSTAL STRUCTURE OF A DELETION MUTANT OF THE TYPE II BETA REGULATORY SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT TYPE II BETA
Authors:Diller, T.C., Xuong, N.H., Taylor, S.S.
Deposit date:1999-08-28
Release date:2001-03-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit.
Structure, 9, 2001
1NE4
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CRYSTAL STRUCTURE OF RP-CAMP BINDING R1A SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J., Jones, J.M., Xuong, N.H., Taylor, S.S.
Deposit date:2002-12-10
Release date:2004-01-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1NE6
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CRYSTAL STRUCTURE OF SP-CAMP BINDING R1A SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J., Jones, J.M., Xuong, N.H., Taylor, S.S.
Deposit date:2002-12-10
Release date:2004-01-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1RGS
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REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
Descriptor:CAMP DEPENDENT PROTEIN KINASE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Authors:Su, Y., Dostmann, W.R.G., Herberg, F.W., Durick, K., Xuong, N.-H., Ten Eyck, L., Taylor, S.S., Varughese, K.I.
Deposit date:1995-06-21
Release date:1996-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains.
Science, 269, 1995
1RL3
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CRYSTAL STRUCTURE OF CAMP-FREE R1A SUBUNIT OF PKA
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory chain
Authors:Wu, J., Brown, S., Xuong, N.-H., Taylor, S.S.
Deposit date:2003-11-24
Release date:2004-07-06
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RIalpha subunit of PKA: a cAMP-free structure reveals a hydrophobic capping mechanism for docking cAMP into site B.
Structure, 12, 2004
1U12
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M. LOTI CYCLIC NUCLEOTIDE BINDING DOMAIN MUTANT
Descriptor:mutant
Authors:Clayton, G.M., Silverman, W.R., Heginbotham, L., Morais-Cabral, J.H.
Deposit date:2004-07-14
Release date:2004-11-30
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel
Cell(Cambridge,Mass.), 119, 2004
1VP6
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M.LOTI ION CHANNEL CYLIC NUCLEOTIDE BINDING DOMAIN
Descriptor:Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel
Authors:Clayton, G.M., Silverman, W.R., Heginbotham, L., Morais-Cabral, J.H.
Deposit date:2004-10-14
Release date:2004-10-26
Modification date:2008-11-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel.
Cell(Cambridge,Mass.), 119, 2004
2D93
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SOLUTION STRUCTURE OF THE CNMP_BINDING DOMAIN OF HUMAN RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6
Descriptor:Rap guanine nucleotide exchange factor 6
Authors:Inoue, K., Muto, Y., Hayashi, F., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-08
Release date:2006-06-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
to be published
2MHF
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SOLUTION STRUCTURE OF THE CYCLIC-NUCLEOTIDE BINDING HOMOLOGY DOMAIN OF A KCNH CHANNEL
Descriptor:Uncharacterized protein
Authors:Li, Q., Ng, H.
Deposit date:2013-11-21
Release date:2014-04-02
Method:SOLUTION NMR
Cite:Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
J.Struct.Biol., 2014
2MNG
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APO STRUCTURE OF HUMAN HCN4 CNBD SOLVED BY NMR
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Akimoto, M., Zhang, Z., Boulton, S., Selvaratnam, R., VanSchouwen, B., Gloyd, M., Accili, E.A., Lange, O.F., Melacini, G.
Deposit date:2014-04-03
Release date:2014-06-04
Modification date:2015-02-11
Method:SOLUTION NMR
Cite:A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
J.Biol.Chem., 289, 2014
2MPF
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SOLUTION STRUCTURE HUMAN HCN2 CNBD IN THE CAMP-UNBOUND STATE
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Saponaro, A., Pauleta, S.R., Cantini, F., Matzapetakis, M., Hammann, C., Banci, L., Thiel, G., Santoro, B., Moroni, A.
Deposit date:2014-05-16
Release date:2014-09-03
Modification date:2014-10-22
Method:SOLUTION NMR
Cite:Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Proc.Natl.Acad.Sci.USA, 111, 2014
2N7G
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STRUCTURE OF THE CYCLIC NUCLEOTIDE-BINDING HOMOLOGY DOMAIN OF THE HERG CHANNEL
Descriptor:Potassium voltage-gated channel subfamily H member 2
Authors:Li, Y., Ng, H., Li, Q., Kang, C.
Deposit date:2015-09-10
Release date:2016-05-18
Method:SOLUTION NMR
Cite:Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome
Sci Rep, 6, 2016
2PQQ
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STRUCTURAL GENOMICS, THE CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF A TRANSCRIPTIONAL REGULATOR FROM STREPTOMYCES COELICOLOR A3(2)
Descriptor:Putative transcriptional regulator
Authors:Tan, K., Xu, X., Zheng, H., Savchenko, A., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-05-02
Release date:2007-06-05
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the N-terminal domain of a transcriptional regulator from Streptomyces coelicolor A3(2)
To be Published
3DN7
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CYCLIC NUCLEOTIDE BINDING REGULATORY PROTEIN FROM CYTOPHAGA HUTCHINSONII.
Descriptor:Cyclic nucleotide binding regulatory protein
Authors:Osipiuk, J., Maltseva, N., Abdullah, J., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-07-01
Release date:2008-08-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of cyclic nucleotide binding regulatory protein from Cytophaga hutchinsonii.
To be Published
3GYD
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CRYSTAL STRUCTURE OF A CYCLIC NUCLEOTIDE-BINDING DOMAIN (MFLA_1926) FROM METHYLOBACILLUS FLAGELLATUS KT AT 1.79 A RESOLUTION
Descriptor:Cyclic nucleotide-binding domain
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-04-03
Release date:2009-04-21
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of cyclic nucleotide-binding domain (YP_546034.1) from Methylobacillus flagellatus KT at 1.79 A resolution
To be published
3IIA
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CRYSTAL STRUCTURE OF APO (91-244) RIA SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Sjoberg, T.J., Kim, C., Kornev, A.P., Taylor, S.S.
Deposit date:2009-07-31
Release date:2010-08-11
Modification date:2015-11-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design.
Mol.Cell Proteomics, 10, 2011
3MDP
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CRYSTAL STRUCTURE OF A PUTATIVE CYCLIC NUCLEOTIDE-BINDING PROTEIN (GMET_1532) FROM GEOBACTER METALLIREDUCENS GS-15 AT 1.90 A RESOLUTION
Descriptor:Cyclic nucleotide-binding domain (CNMP-BD) protein
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-03-30
Release date:2010-05-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a Putative Cyclic nucleotide-binding protein (Gmet_1532) from Geobacter metallireducens GS-15 at 1.90 A resolution
To be published
3OCP
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CRYSTAL STRUCTURE OF CAMP BOUND CGMP-DEPENDENT PROTEIN KINASE(92-227)
Descriptor:PRKG1 protein (E.C.2.7.11.12)
Authors:Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.
Deposit date:2010-08-10
Release date:2011-05-11
Modification date:2011-05-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
3OD0
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CRYSTAL STRUCTURE OF CGMP BOUND CGMP-DEPENDENT PROTEIN KINASE(92-227)
Descriptor:PRKG1 protein (E.C.2.7.11.12)
Authors:Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.
Deposit date:2010-08-10
Release date:2011-05-11
Modification date:2011-05-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
3OF1
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CRYSTAL STRUCTURE OF BCY1, THE YEAST REGULATORY SUBUNIT OF PKA
Descriptor:cAMP-dependent protein kinase regulatory subunit
Authors:Rinaldi, J., Wu, J., Yang, J., Ralston, C.Y., Sankaran, B., Moreno, S., Taylor, S.S.
Deposit date:2010-08-13
Release date:2010-12-01
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling.
Structure, 18, 2010
3OGJ
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CRYSTAL STRUCTURE OF PARTIAL APO (92-227) OF CGMP-DEPENDENT PROTEIN KINASE
Descriptor:PRKG1 protein (E.C.2.7.11.12)
Authors:Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.
Deposit date:2010-08-16
Release date:2011-05-11
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
3PLQ
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CRYSTAL STRUCTURE OF PKA TYPE I REGULATORY SUBUNIT BOUND WITH RP-8-BR-CAMPS
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Swaminathan, K.
Deposit date:2010-11-15
Release date:2010-12-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: Conformational selection highlights a new concept in allosteric inhibitor design
To be Published
3PNA
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CRYSTAL STRUCTURE OF CAMP BOUND (91-244)RIA SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE
Descriptor:cAMP-dependent protein kinase type I-alpha regulatory subunit (E.C.2.7.1.37)
Authors:Kim, C., Taylor, S.
Deposit date:2010-11-18
Release date:2011-02-09
Modification date:2011-03-23
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design.
Mol Cell Proteomics, 10, 2011
3SHR
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CRYSTAL STRUCTURE OF CGMP-DEPENDENT PROTEIN KINASE REVEALS NOVEL SITE OF INTERCHAIN COMMUNICATION
Descriptor:cGMP-dependent protein kinase 1 (E.C.2.7.11.12)
Authors:Osborne, B.W., Wu, J., Taylor, S.S., Dostmann, W.R.
Deposit date:2011-06-16
Release date:2011-09-21
Modification date:2011-10-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication.
Structure, 19, 2011
4F8A
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CYCLIC NUCLEOTIDE BINDING-HOMOLOGY DOMAIN FROM MOUSE EAG1 POTASSIUM CHANNEL
Descriptor:Cyclic nucleotide binding-homology domain
Authors:Marques-Carvalho, M.J., Sahoo, N., Muskett, F.W., Vieira-Pires, R.S., Gabant, G., Cadene, M., Schonherr, R., Morais-Cabral, J.H.
Deposit date:2012-05-17
Release date:2012-07-11
Modification date:2012-10-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.
J.Mol.Biol., 423, 2012
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