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1E5O
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1e5o
ENDOTHIAPEPSIN COMPLEX WITH INHIBITOR DB2
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.23)
Authors:Read, J.A., Cooper, J.B., Toldo, L., Bailey, D.
Deposit date:2000-07-28
Release date:2000-09-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases.
Crystallographic Studies Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases, 1999
1E80
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1e80
ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD56133
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.23)
Authors:Read, J.A., Cooper, J.B., Toldo, L., Rippmann, F., Raddatz, P.
Deposit date:2000-09-15
Release date:2000-09-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases.
Ph D Thesis, 1999
1E81
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1e81
ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD61395
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.23)
Authors:Read, J.A., Cooper, J.B., Toldo, L., Rippmann, F., Raddatz, P.
Deposit date:2000-09-15
Release date:2000-10-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases.
Thesis, 1999
1E82
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1e82
ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD59601
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.23)
Authors:Read, J.A., Cooper, J.B., Toldo, L., Rippmann, F., Raddatz, P.
Deposit date:2000-09-15
Release date:2000-10-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases.
Thesis, 1999
1EAG
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1eag
SECRETED ASPARTIC PROTEINASE (SAP2) FROM CANDIDA ALBICANS COMPLEXED WITH A70450
Descriptor:ASPARTIC PROTEINASE (SAP2 GENE PRODUCT), 4-METHYLPIPERAZIN-1-YL CARBONYL GROUP, ETHYLAMINOBENZYLMETHYLCARBONYL GROUP, 1-AMINO-1-CARBONYL PENTANE, 1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE, 2,3-DIMETHYL-BUTYRALDEHYDE, BUTYLAMINE
Authors:Cutfield, J.F., Cutfield, S.M.
Deposit date:1996-05-31
Release date:1996-12-23
Modification date:2012-11-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors.
Structure, 3, 1995
1EED
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1eed
X-RAY CRYSTALLOGRAPHIC ANALYSIS OF INHIBITION OF ENDOTHIAPEPSIN BY CYCLOHEXYL RENIN INHIBITORS
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22) COMPLEX WITH THE CYCLOHEXYL RENIN INHIBITOR PD125754
Authors:Blundell, T.L., Frazao, C., Cooper, J.B.
Deposit date:1992-06-15
Release date:1994-01-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors.
Biochemistry, 31, 1992
1ENT
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1ent
X-RAY ANALYSES OF ASPARTIC PROTEINASES. THE THREE-DIMENSIONAL STRUCTURE AT 2.1 ANGSTROMS RESOLUTION OF ENDOTHIAPEPSIN
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22) COMPLEX WITH THE INHIBITOR PD130328
Authors:Blundell, T.L., Dealwis, C.G.
Deposit date:1992-03-11
Release date:1994-01-31
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray analyses of aspartic proteinases. The three-dimensional structure at 2.1 A resolution of endothiapepsin.
J.Mol.Biol., 211, 1990
1EPL
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1epl
A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH PS1 (PRO LEU GLU PSA ARG LEU)
Authors:Al-Karadaghi, S., Cooper, J.B., Strop, P., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1EPM
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1epm
A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH PS2 (THR PHE GLN ALA PSA LEU ARG GLU)
Authors:Crawford, M., Cooper, J.B., Strop, P., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1EPN
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1epn
A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH CP-80,794 (MOR PHE CYS+CH3 NOR)
Authors:Crawford, M., Cooper, J.B., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1EPO
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1epo
ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)
Authors:Veerapandian, B., Cooper, J.B., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Direct observation by X-ray analysis of the tetrahedral intermediate of aspartic proteinases.
Protein Sci., 1, 1992
1EPP
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1epp
ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-130,693 (MAS PHE LYS+MTF STA MBA)
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22)COMPLEXED WITH PD-130,693 (MAS PHE LYS+MTF STA MBA)
Authors:Wallace, B.A., Cooper, J.B., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors.
J.Med.Chem., 36, 1993
1EPQ
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1epq
ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-133,450 (SOT PHE GLY+SCC GCL)
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH PD-133,450 (SOT PHE GLY+SCC GCL)
Authors:Dealwis, C., Cooper, J.B., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors.
J.Med.Chem., 36, 1993
1EPR
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1epr
ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-135,040
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH PD-135,040
Authors:Badasso, M., Crawford, M., Cooper, J.B., Blundell, T.L.
Deposit date:1994-07-27
Release date:1994-12-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
Protein Sci., 3, 1994
1ER8
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1er8
THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.6) COMPLEX WITH H-77
Authors:Hemmings, A.M., Veerapandian, B., Szelke, M., Cooper, J.B., Blundell, T.L.
Deposit date:1989-10-16
Release date:1991-10-15
Modification date:2011-05-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
1GKT
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1gkt
NEUTRON LAUE DIFFRACTION STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH TRANSITION STATE ANALOGUE INHIBITOR H261
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22), INHIBITOR, H261
Authors:Coates, L., Erskine, P.T., Wood, S.P., Myles, D.A.A., Cooper, J.B.
Deposit date:2001-08-20
Release date:2001-11-20
Modification date:2013-01-16
Method:NEUTRON DIFFRACTION (2.1 Å)
Cite:A Neutron Laue Diffraction Study of Endothiapepsin: Implications for the Aspartic Proteinase Mechanism
Biochemistry, 40, 2001
1GVT
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1gvt
ENDOTHIAPEPSIN COMPLEX WITH CP-80,794
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22)
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVU
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1gvu
ENDOTHIAPEPSIN COMPLEX WITH H189
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22), INHIBITOR, H189
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVV
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1gvv
FIVE ATOMIC RESOLUTION STRUCTURES OF ENDOTHIAPEPSIN INHIBITOR COMPLEXES; IMPLICATIONS FOR THE ASPARTIC PROTEINASE MECHANISM
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22)
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVW
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1gvw
ENDOTHIAPEPSIN COMPLEX WITH PD-130,328
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22)
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1GVX
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1gvx
ENDOTHIAPEPSIN COMPLEXED WITH H256
Descriptor:ENDOTHIAPEPSIN (E.C.3.4.23.22), INHIBITOR H256
Authors:Coates, L., Erskine, P.T., Crump, M.P., Wood, S.P., Cooper, J.B.
Deposit date:2002-02-27
Release date:2002-07-04
Modification date:2011-12-07
Method:X-RAY DIFFRACTION (1 Å)
Cite:Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism
J.Mol.Biol., 318, 2002
1IBQ
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1ibq
ASPERGILLOPEPSIN FROM ASPERGILLUS PHOENICIS
Descriptor:ASPERGILLOPEPSIN (E.C.3.4.23.18)
Authors:Cho, S.W., Shin, W.
Deposit date:2001-03-28
Release date:2001-07-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure of aspergillopepsin I from Aspergillus phoenicis: variations of the S1'-S2 subsite in aspartic proteinases.
Acta Crystallogr.,Sect.D, 57, 2001
1IZD
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1izd
CRYSTAL STRUCTURE OF ASPERGILLUS ORYZAE ASPARTIC PROTEINASE
Descriptor:aspartic proteinase II-1
Authors:Kamitori, S., Ohtaki, A., Ino, H., Takeuchi, M.
Deposit date:2002-10-02
Release date:2003-03-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structures of Aspergillus oryzae Aspartic Proteinase and its Complex with an Inhibitor Pepstatin at 1.9 A Resolution
J.Mol.Biol., 326, 2003
1IZE
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1ize
CRYSTAL STRUCTURE OF ASPERGILLUS ORYZAE ASPARTIC PROTEINASE COMPLEXED WITH PEPSTATIN
Descriptor:Aspartic proteinase
Authors:Kamitori, S., Ohtaki, A., Ino, H., Takeuchi, M.
Deposit date:2002-10-02
Release date:2003-03-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of Aspergillus oryzae aspartic proteinase and its complex with an inhibitor pepstatin at 1.9A resolution.
J.Mol.Biol., 326, 2003
1J71
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1j71
STRUCTURE OF THE EXTRACELLULAR ASPARTIC PROTEINASE FROM CANDIDA TROPICALIS YEAST.
Descriptor:Aspartic proteinase (E.C.3.4.23.24)
Authors:Symersky, J., Monod, M., Foundling, S.I.
Deposit date:2001-05-15
Release date:2001-05-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structure of the extracellular aspartic proteinase from Candida tropicalis yeast.
Biochemistry, 36, 1997
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