5D68
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CRYSTAL STRUCTURE OF KRIT1 ARD-FERM
Descriptor:Krev interaction trapped protein 1
Authors:Zhang, R., Li, X., Boggon, T.J.
Deposit date:2015-08-11
Release date:2015-10-21
Modification date:2015-12-02
Method:X-RAY DIFFRACTION (2.908 Å)
Cite:Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
5CZY
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CRYSTAL STRUCTURE OF LEGAS4
Descriptor:Eukaryotic huntingtin interacting protein B
Authors:Son, J., Hwang, K.Y., Lee, W.C.
Deposit date:2015-08-01
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4
Biochem.Biophys.Res.Commun., 465, 2015
3J9P
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STRUCTURE OF THE TRPA1 ION CHANNEL DETERMINED BY ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily A member 1
Authors:Paulsen, C.E., Armache, J.-P., Gao, Y., Cheng, Y., Julius, D.
Deposit date:2015-02-14
Release date:2015-04-08
Modification date:2015-04-29
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 520, 2015
3J9J
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STRUCTURE OF THE CAPSAICIN RECEPTOR, TRPV1, DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Wang, R.Y.-R., Barad, B.A., Fraser, J.S., DiMaio, F.
Deposit date:2015-02-02
Release date:2015-09-02
Modification date:2015-10-14
Method:ELECTRON MICROSCOPY
Cite:EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12, 2015
4RLV
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CRYSTAL STRUCTURE OF ANKB 24 ANKYRIN REPEATS IN COMPLEX WITH ANKR AUTOINHIBITION SEGMENT
Descriptor:Ankyrin-1, Ankyrin-2
Authors:Wei, Z., Wang, C., Zhang, M.
Deposit date:2014-10-18
Release date:2014-11-26
Modification date:2015-05-20
Method:X-RAY DIFFRACTION (3.4945 Å)
Cite:Structural basis of diverse membrane target recognitions by ankyrins.
Elife, 3, 2014
4RLY
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CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS (R1-R9) IN COMPLEX WITH NAV1.2 ANKYRIN BINDING DOMAIN
Descriptor:Nav1.2 - AnkB chimera
Authors:Wei, Z., Wang, C., Zhang, M.
Deposit date:2014-10-18
Release date:2014-11-26
Modification date:2015-05-20
Method:X-RAY DIFFRACTION (2.5032 Å)
Cite:Structural basis of diverse membrane target recognitions by ankyrins.
Elife, 3, 2014
4QQM
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CRYSTAL STRUCTURE OF RFXANK ANKYRIN REPEATS IN COMPLEX WITH RFX7
Descriptor:DNA-binding protein RFXANK, DNA-binding protein RFX7
Authors:Tempel, W., Xu, C., Dong, A., Li, Y., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2014-06-27
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of RFXANK ankyrin repeats in complex with RFX7
To be Published
4OT9
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF P100/NF-KB2
Descriptor:Nuclear factor NF-kappa-B p100 subunit
Authors:Tao, Z.H., Huang, D.B., Fusco, A., Gupta, K., Ware, C.F., Duynne, G.V.
Deposit date:2014-02-13
Release date:2015-01-14
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OAU
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COMPLETE HUMAN RNASE L IN COMPLEX WITH BIOLOGICAL ACTIVATORS.
Descriptor:RNase L
Authors:Han, Y., Donovan, J., Rath, S., Whitney, G., Chitrakar, A., Korennykh, A.
Deposit date:2014-01-06
Release date:2014-03-12
Modification date:2014-04-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science, 343, 2014
4OAV
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COMPLETE HUMAN RNASE L IN COMPLEX WITH 2-5A (5'-PPP HEPTAMER), AMPPCP AND RNA SUBSTRATE.
Descriptor:RNase L
Authors:Han, Y., Donovan, J., Rath, S., Whitney, G., Chitrakar, A., Korennykh, A.
Deposit date:2014-01-06
Release date:2014-03-12
Modification date:2014-04-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science, 343, 2014
3J5P
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STRUCTURE OF TRPV1 ION CHANNEL DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Modification date:2013-12-18
Method:ELECTRON MICROSCOPY (3.275 Å)
Cite:Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Nature, 504, 2013
3J5Q
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STRUCTURE OF TRPV1 ION CHANNEL IN COMPLEX WITH DKTX AND RTX DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1, Double-knot toxin
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Modification date:2013-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
3J5R
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RECONSTRUCTION OF TRPV1 ION CHANNEL IN COMPLEX WITH CAPSAICIN BY SINGLE PARTICLE CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Modification date:2013-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
4K5C
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FROM DARPINS TO LOOPDARPINS: NOVEL LOOPDARPIN DESIGN ALLOWS THE SELECTION OF LOW PICOMOLAR BINDERS IN A SINGLE ROUND OF RIBOSOME DISPLAY
Descriptor:Loop Designed Ankyrin Repeat Protein Nran1_G06_C
Authors:Schilling, J., Schoeppe, J., Plueckthun, A.
Deposit date:2013-04-14
Release date:2013-11-13
Modification date:2014-03-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display
J.Mol.Biol., 426, 2014
4HQD
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR265.
Descriptor:Engineered Protein OR265
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P-S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-10-25
Release date:2012-11-14
Method:X-RAY DIFFRACTION (2.433 Å)
Cite:Crystal Structure of Engineered Protein OR265.
To be Published
4HB5
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR267.
Descriptor:Engineered Protein
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P-S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-09-27
Release date:2012-10-10
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Crystal Structure of Engineered Protein.
To be Published
4GPM
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR264.
Descriptor:Engineered Protein OR264
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P-.S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-21
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal Structure of Engineered Protein OR264.
To be Published
4GMR
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR266.
Descriptor:OR266
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P-S., Mao, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-16
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.377 Å)
Cite:Crystal Structure of Engineered Protein OR266.
To be Published
4G8K
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INTACT SENSOR DOMAIN OF HUMAN RNASE L IN THE INACTIVE SIGNALING STATE
Descriptor:2-5A-dependent ribonuclease (E.C.3.1.26.-)
Authors:Han, Y., Whitney, G., Donovan, J., Korennykh, A.
Deposit date:2012-07-23
Release date:2012-10-31
Modification date:2012-11-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes.
Cell Rep, 2, 2012
4G8L
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ACTIVE STATE OF INTACT SENSOR DOMAIN OF HUMAN RNASE L WITH 2-5A BOUND
Descriptor:2-5A-dependent ribonuclease (E.C.3.1.26.-)
Authors:Han, Y., Whitney, G., Donovan, J., Korennykh, A.
Deposit date:2012-07-23
Release date:2012-10-31
Modification date:2012-11-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes.
Cell Rep, 2, 2012
4DX1
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CRYSTAL STRUCTURE OF THE HUMAN TRPV4 ANKYRIN REPEAT DOMAIN
Descriptor:Transient receptor potential cation channel subfamily V member 4
Authors:Inada, H., Gaudet, R.
Deposit date:2012-02-27
Release date:2012-07-18
Modification date:2012-12-19
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
Biochemistry, 51, 2012
4DX2
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CRYSTAL STRUCTURE OF THE HUMAN TRPV4 ANKYRIN REPEAT DOMAIN
Descriptor:Transient receptor potential cation channel subfamily V member 4
Authors:Inada, H., Gaudet, R.
Deposit date:2012-02-27
Release date:2012-07-18
Modification date:2012-12-19
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
Biochemistry, 51, 2012
4DUI
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DARPIN D1 BINDING TO TUBULIN BETA CHAIN (NOT IN COMPLEX)
Descriptor:DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1
Authors:Pecqueur, L., Duellberg, C., Dreier, B., Wang, Q., Jiang, C., Pluckthun, A., Surrey, T., Gigant, B., Knossow, M.
Deposit date:2012-02-22
Release date:2013-02-27
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:An Anti-Tubulin Darpin Caps the Microtubule Plus-End
To be Published
3V79
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STRUCTURE OF HUMAN NOTCH1 TRANSCRIPTION COMPLEX INCLUDING CSL, RAM, ANK, AND MAML-1 ON HES-1 PROMOTER DNA SEQUENCE
Descriptor:Transcription activation/repressor/DNA complex
Authors:Nam, Y., Sliz, P., Blacklow, S.
Deposit date:2011-12-20
Release date:2012-02-15
Modification date:2012-03-21
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes.
Structure, 20, 2012
3V30
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CRYSTAL STRUCTURE OF THE PEPTIDE BOUND COMPLEX OF THE ANKYRIN REPEAT DOMAINS OF HUMAN RFXANK
Descriptor:DNA-binding protein RFXANK, DNA-binding protein RFX5
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Modification date:2012-06-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
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