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1EXT
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1ext
EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR
Authors:Naismith, J.H., Sprang, S.R.
Deposit date:1996-07-03
Release date:1997-01-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the extracellular domain of the type I tumor necrosis factor receptor.
Structure, 4, 1996
1FT4
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1ft4
PHOTOCHEMICALLY-ENHANCED BINDING OF SMALL MOLECULES TO THE TUMOR NECROSIS FACTOR RECEPTOR-1
Descriptor:SOLUBLE TUMOR NECROSIS FACTOR RECEPTOR 1
Authors:Muckelbauer, J.K., Chang, C.-H.
Deposit date:2000-09-11
Release date:2001-10-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha.
Proc.Natl.Acad.Sci.USA, 98, 2001
1NCF
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1ncf
A NEW PARADIGM FOR TUMOR NECROSIS FACTOR SIGNALLING
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR
Authors:Naismith, J.H., Sprang, S.R.
Deposit date:1994-10-12
Release date:1995-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor.
J.Biol.Chem., 270, 1995
2UWI
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2uwi
STRUCTURE OF CRME, A POXVIRUS TNF RECEPTOR
Descriptor:CRME PROTEIN
Authors:Graham, S.C., Bahar, M.W., Abrescia, N.G., Smith, G.L., Stuart, D.I., Grimes, J.M.
Deposit date:2007-03-22
Release date:2007-07-10
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Crme, a Virus-Encoded Tumour Necrosis Factor Receptor.
J.Mol.Biol., 372, 2007
3ME4
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3me4
CRYSTAL STRUCTURE OF MOUSE RANK
Descriptor:Tumor necrosis factor receptor superfamily member 11A
Authors:Walter, S.W., Liu, C., Zhu, X., Wu, Y., Owens, R.J., Stuart, D.I., Gao, B., Ren, J.
Deposit date:2010-03-31
Release date:2010-06-02
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and Functional Insights of RANKL-RANK Interaction and Signaling.
J.Immunol., 2010
3MHD
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3mhd
CRYSTAL STRUCTURE OF DCR3
Descriptor:Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2010-04-07
Release date:2011-02-23
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
4FHQ
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4fhq
CRYSTAL STRUCTURE OF HVEM
Descriptor:Tumor necrosis factor receptor superfamily member 14
Authors:Liu, W., Zhan, C., Patskovsky, Y., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-06-06
Release date:2012-07-18
Modification date:2012-07-25
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Crystal Structure of HVEM
To be Published
4I9X
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4i9x
CRYSTAL STRUCTURE OF HUMAN CYTOMEGALOVIRUS GLYCOPROTEIN UL141 TARGETING THE DEATH RECEPTOR TRAIL-R2
Descriptor:Protein UL141, Tumor necrosis factor receptor superfamily member 10B
Authors:Nemcovicova, I., Zajonc, D.M.
Deposit date:2012-12-05
Release date:2013-04-03
Modification date:2013-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions.
Plos Pathog., 9, 2013
1D0G
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1d0g
CRYSTAL STRUCTURE OF DEATH RECEPTOR 5 (DR5) BOUND TO APO2L/TRAIL
Descriptor:DEATH RECEPTOR 5
Authors:Hymowitz, S.G., Christinger, H.W., Fuh, G., O'Connell, M.P., Kelley, R.F., Ashkenazi, A., de Vos, A.M.
Deposit date:1999-09-09
Release date:1999-10-22
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.
Mol.Cell, 4, 1999
1DU3
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1du3
CRYSTAL STRUCTURE OF TRAIL-SDR5
Descriptor:DEATH RECEPTOR 5
Authors:Cha, S.-S., Sung, B.-J., Oh, B.-H.
Deposit date:2000-01-14
Release date:2000-09-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
J.Biol.Chem., 275, 2000
1JMA
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1jma
CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM
Descriptor:HERPESVIRUS ENTRY MEDIATOR, GLYCOPROTEIN D
Authors:Carfi, A., Willis, S.H., Whitbeck, J.C., Krummenacker, C., Cohen, G.H., Eisenberg, R.J., Wiley, D.C.
Deposit date:2001-07-17
Release date:2001-09-26
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Herpes simplex virus glycoprotein D bound to the human receptor HveA.
Mol.Cell, 8, 2001
4KGG
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4kgg
CRYSTAL STRUCTURE OF LIGHT MUTANT2 AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14
Authors:Liu, W., Bonanno, J.B., Zhan, C., Kumar, P.R., Toro, R., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-04-29
Release date:2013-08-07
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Crystal Structure of Light and Dcr3 Complex
To be Published
4KGQ
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4kgq
CRYSTAL STRUCTURE OF A HUMAN LIGHT LOOP MUTANT IN COMPLEX WITH DCR3
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14
Authors:Liu, W., Zhan, C., Bonanno, J.B., Sampathkumar, P., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-04-29
Release date:2013-07-10
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal Structure of Light and Dcr3 Complex
To be Published
4MSV
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4msv
CRYSTAL STRUCTURE OF FASL AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 6
Authors:Liu, W., Ramagopal, U.A., Zhan, C., Bonanno, J.B., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-09-18
Release date:2013-11-27
Modification date:2014-03-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of FASL and DcR3 complex
To be Published
4MXW
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4mxw
STRUCTURE OF HETEROTRIMERIC LYMPHOTOXIN LTA1B2 BOUND TO LYMPHOTOXIN BETA RECEPTOR LTBR AND ANTI-LTA FAB
Descriptor:Tumor necrosis factor receptor superfamily member 3, anti-Lymphotoxin alpha antibody light chain, anti-Lymphotoxin alpha antibody heavy chain, Lymphotoxin-alpha, Lymphotoxin-beta
Authors:Sudhamsu, J., Yin, J.P., Hymowitz, S.G.
Deposit date:2013-09-26
Release date:2013-11-13
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction.
Proc.Natl.Acad.Sci.USA, 110, 2013
1D4V
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1d4v
CRYSTAL STRUCTURE OF TRAIL-DR5 COMPLEX
Descriptor:TNF-RELATED APOPTOSIS INDUCING LIGAND
Authors:Mongkolsapaya, J., Grimes, J.M., Stuart, D.I., Jones, E.Y., Screaton, G.R.
Deposit date:1999-10-06
Release date:1999-11-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
Nat.Struct.Biol., 6, 1999
1SG1
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1sg1
CRYSTAL STRUCTURE OF THE RECEPTOR-LIGAND COMPLEX BETWEEN NERVE GROWTH FACTOR AND THE COMMON NEUROTROPHIN RECEPTOR P75
Descriptor:Beta-nerve growth factor
Authors:He, X.L., Garcia, K.C.
Deposit date:2004-02-22
Release date:2004-06-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
Science, 304, 2004
1TNR
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1tnr
CRYSTAL STRUCTURE OF THE SOLUBLE HUMAN 55 KD TNF RECEPTOR-HUMAN TNF-BETA COMPLEX: IMPLICATIONS FOR TNF RECEPTOR ACTIVATION
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR P55 (EXTRACELLULAR DOMAIN) COMPLEXED WITH TUMOR NECROSIS FACTOR-BETA
Authors:Banner, D.W.
Deposit date:1994-05-09
Release date:1994-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Cell(Cambridge,Mass.), 73, 1993
1ZA3
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1za3
THE CRYSTAL STRUCTURE OF THE YSD1 FAB BOUND TO DR5
Descriptor:Fab-YSd1 light chain, Fab-YSd1 heavy chain, Tumor necrosis factor receptor superfamily member 10B precursor
Authors:Fellouse, F.A., Li, B., Compaan, D.M., Peden, A.A., Hymowitz, S.G., Sidhu, S.S.
Deposit date:2005-04-05
Release date:2005-06-14
Modification date:2014-02-05
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Molecular recognition by a binary code.
J.Mol.Biol., 348, 2005
2AW2
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2aw2
CRYSTAL STRUCTURE OF THE HUMAN BTLA-HVEM COMPLEX
Descriptor:B and T lymphocyte attenuator, Tumor necrosis factor receptor superfamily member 14
Authors:Compaan, D.M., Gonzalez, L.C., Tom, I., Loyet, K.M., Eaton, D., Hymowitz, S.G.
Deposit date:2005-08-31
Release date:2005-09-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Attenuating Lymphocyte Activity: the crystal structure of the BTLA-HVEM complex
J.Biol.Chem., 280, 2005
2H9G
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2h9g
CRYSTAL STRUCTURE OF PHAGE DERIVED FAB BDF1 WITH HUMAN DEATH RECEPTOR 5 (DR5)
Descriptor:Phage derived fab BdF1, light chain, Phage derived fab BdF1, heavy chain, Tumor necrosis factor receptor superfamily member 10B precursor
Authors:Hymowitz, S.G., Compaan, D.M.
Deposit date:2006-06-09
Release date:2006-08-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists.
J.Mol.Biol., 361, 2006
2HEV
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2hev
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN OX40L AND OX40
Descriptor:Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4
Authors:Hymowitz, S.G., Compaan, D.M.
Deposit date:2006-06-22
Release date:2006-08-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
2HEY
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2hey
CRYSTAL STRUCTURE OF MURINE OX40L BOUND TO HUMAN OX40
Descriptor:Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4
Authors:Hymowitz, S.G.
Deposit date:2006-06-22
Release date:2006-08-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
3ALQ
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3alq
CRYSTAL STRUCTURE OF TNF-TNFR2 COMPLEX
Descriptor:Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1B
Authors:Mukai, Y., Nakamura, T., Yamagata, Y., Tsutsumi, Y.
Deposit date:2010-08-06
Release date:2010-11-17
Modification date:2010-12-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Solution of the Structure of the TNF-TNFR2 Complex
Sci.Signal., 3, 2010
3BUK
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3buk
CRYSTAL STRUCTURE OF THE NEUROTROPHIN-3 AND P75NTR SYMMETRICAL COMPLEX
Descriptor:Neurotrophin-3, Tumor necrosis factor receptor superfamily member 16
Authors:Jiang, T., Gong, Y., Cao, P., Yu, H.J.
Deposit date:2008-01-02
Release date:2008-07-15
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.
Nature, 454, 2008
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