1EXT
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EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR
Authors:Naismith, J.H., Sprang, S.R.
Deposit date:1996-07-03
Release date:1997-01-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the extracellular domain of the type I tumor necrosis factor receptor.
Structure, 4, 1996
1FT4
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PHOTOCHEMICALLY-ENHANCED BINDING OF SMALL MOLECULES TO THE TUMOR NECROSIS FACTOR RECEPTOR-1
Descriptor:SOLUBLE TUMOR NECROSIS FACTOR RECEPTOR 1
Authors:Muckelbauer, J.K., Chang, C.-H.
Deposit date:2000-09-11
Release date:2001-10-12
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha.
Proc.Natl.Acad.Sci.USA, 98, 2001
1NCF
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A NEW PARADIGM FOR TUMOR NECROSIS FACTOR SIGNALLING
Descriptor:TUMOR NECROSIS FACTOR RECEPTOR
Authors:Naismith, J.H., Sprang, S.R.
Deposit date:1994-10-12
Release date:1995-12-07
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor.
J.Biol.Chem., 270, 1995
1ZA3
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THE CRYSTAL STRUCTURE OF THE YSD1 FAB BOUND TO DR5
Descriptor:Fab-YSd1 light chain, Fab-YSd1 heavy chain, Tumor necrosis factor receptor superfamily member 10B precursor
Authors:Fellouse, F.A., Li, B., Compaan, D.M., Peden, A.A., Hymowitz, S.G., Sidhu, S.S.
Deposit date:2005-04-05
Release date:2005-06-14
Modification date:2014-02-05
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Molecular recognition by a binary code.
J.Mol.Biol., 348, 2005
2H9G
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CRYSTAL STRUCTURE OF PHAGE DERIVED FAB BDF1 WITH HUMAN DEATH RECEPTOR 5 (DR5)
Descriptor:Phage derived fab BdF1, light chain, Phage derived fab BdF1, heavy chain, Tumor necrosis factor receptor superfamily member 10B precursor
Authors:Hymowitz, S.G., Compaan, D.M.
Deposit date:2006-06-09
Release date:2006-08-08
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists.
J.Mol.Biol., 361, 2006
2HEV
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN OX40L AND OX40
Descriptor:Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4
Authors:Hymowitz, S.G., Compaan, D.M.
Deposit date:2006-06-22
Release date:2006-08-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
2HEY
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CRYSTAL STRUCTURE OF MURINE OX40L BOUND TO HUMAN OX40
Descriptor:Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4
Authors:Hymowitz, S.G.
Deposit date:2006-06-22
Release date:2006-08-29
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
2UWI
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STRUCTURE OF CRME, A POXVIRUS TNF RECEPTOR
Descriptor:CRME PROTEIN
Authors:Graham, S.C., Bahar, M.W., Abrescia, N.G., Smith, G.L., Stuart, D.I., Grimes, J.M.
Deposit date:2007-03-22
Release date:2007-07-10
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Crme, a Virus-Encoded Tumour Necrosis Factor Receptor.
J.Mol.Biol., 372, 2007
3ME4
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CRYSTAL STRUCTURE OF MOUSE RANK
Descriptor:Tumor necrosis factor receptor superfamily member 11A
Authors:Walter, S.W., Liu, C., Zhu, X., Wu, Y., Owens, R.J., Stuart, D.I., Gao, B., Ren, J.
Deposit date:2010-03-31
Release date:2010-06-02
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and Functional Insights of RANKL-RANK Interaction and Signaling.
J.Immunol., 2010
3MHD
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CRYSTAL STRUCTURE OF DCR3
Descriptor:Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2010-04-07
Release date:2011-02-23
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3QO4
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THE CRYSTAL STRUCTURE OF DEATH RECEPTOR 6
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Kuester, M., Kemmerzehl, S., Dahms, S.O., Roeser, D., Than, M.E.
Deposit date:2011-02-09
Release date:2011-05-18
Modification date:2012-02-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
3THM
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CRYSTAL STRUCTURE OF FAS RECEPTOR EXTRACELLULAR DOMAIN IN COMPLEX WITH FAB EP6B_B01
Descriptor:Fab EP6b_B01, light chain, Fab EP6b_B01, heavy chain, Tumor necrosis factor receptor superfamily member 6
Authors:Zuger, S., Stirnimann, C., Briand, C., Grutter, M.G.
Deposit date:2011-08-19
Release date:2012-05-09
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3TJE
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CRYSTAL STRUCTURE OF FAS RECEPTOR EXTRACELLULAR DOMAIN IN COMPLEX WITH FAB E09
Descriptor:Fab E09, light chain, Fab E09, heavy chain, Tumor necrosis factor receptor superfamily member 6
Authors:Zuger, S., Stirnimann, C., Briand, C., Grutter, M.G.
Deposit date:2011-08-24
Release date:2012-05-09
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3U3P
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Modification date:2013-07-10
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3Q
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Modification date:2013-07-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3U3S
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Modification date:2013-07-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3U3T
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Modification date:2012-07-11
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3V
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Modification date:2012-07-11
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3WVT
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STRUCTURAL AND BIOCHEMICAL STUDY OF EQUINE LENTIVIRUS RECEPTOR 1
Descriptor:ELR1
Authors:Qian, L.
Deposit date:2014-06-07
Release date:2015-06-10
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural insight into equine lentivirus receptor 1
Protein Sci., 24, 2015
3X3F
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TRAIL-R2 EXTRACELLULAR REGION COMPLEXED TO A FAB FRAGMENT FROM HUMAN AGONIST ANTIBODY KMTR2
Descriptor:Heavy chain of KMTR2, Light chain of KMTR2, Tumor necrosis factor receptor superfamily member 10B
Authors:Tamada, T.
Deposit date:2015-01-20
Release date:2015-12-23
Modification date:2015-12-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:TRAIL-R2 Superoligomerization Induced by Human Monoclonal Agonistic Antibody KMTR2
SCI REP, 2015
4FHQ
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CRYSTAL STRUCTURE OF HVEM
Descriptor:Tumor necrosis factor receptor superfamily member 14
Authors:Liu, W., Zhan, C., Patskovsky, Y., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-06-06
Release date:2012-07-18
Modification date:2015-09-16
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
Mol Biotechnol, 57, 2015
4OD2
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF AN ANTI-DR5 ANTIBODY BOUND TO DR5
Descriptor:Fab fragment of drozitumab, light chain, Fab fragment of drozitumab, heavy chain, Tumor necrosis factor receptor superfamily member 10B
Authors:Hymowitz, S.G., Compaan, D.
Deposit date:2014-01-09
Release date:2014-02-05
Modification date:2014-04-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5.
Cell Death Differ., 15, 2008
5DMI
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STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE CD40 IN COMPLEX WITH CHI220 FAB
Descriptor:Tumor necrosis factor receptor superfamily member 5, Chi220 Fab heavy chain, Chi220 Fab light chain
Authors:Sheriff, S.
Deposit date:2015-09-08
Release date:2016-06-01
Modification date:2016-07-20
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
J.Mol.Biol., 428, 2016
5DMJ
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STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE CD40 IN COMPLEX WITH 3H56-5 DAB
Descriptor:Tumor necrosis factor receptor superfamily member 5, 3H65-5 domain antibody (dAb)
Authors:Sheriff, S.
Deposit date:2015-09-08
Release date:2016-06-01
Modification date:2016-07-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
J.Mol.Biol., 428, 2016
5IHL
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STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE CD40 IN COMPLEX WITH 3H56-5 DAB
Descriptor:Tumor necrosis factor receptor superfamily member 5, 3H56-5 domain antibody (dAb)
Authors:Sheriff, S.
Deposit date:2016-02-29
Release date:2016-06-01
Modification date:2016-07-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
J.Mol.Biol., 428, 2016
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