1WXT
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SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMAN HYPOTHETICAL PROTEIN FLJ21522
Descriptor:Hypothetical protein FLJ21522
Authors:Yoneyama, M., Saito, K., Tochio, N., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-01
Release date:2005-08-01
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of human hypothetical protein FLJ21522
To be Published
1A0N
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NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES
Descriptor:PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR, FYN
Authors:Renzoni, D.A., Pugh, D.J.R., Siligardi, G., Das, P., Morton, C.J., Rossi, C., Waterfield, M.D., Campbell, I.D., Ladbury, J.E.
Deposit date:1997-12-05
Release date:1998-02-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.
Biochemistry, 35, 1996
1ABO
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE
Descriptor:ABL TYROSINE KINASE, 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES
Authors:Musacchio, A., Wilmanns, M., Saraste, M.
Deposit date:1995-05-19
Release date:1995-10-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1ABQ
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CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN
Descriptor:ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN
Authors:Musacchio, A., Wilmanns, M., Saraste, M.
Deposit date:1995-05-19
Release date:1995-10-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1AOJ
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THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER
Descriptor:EPS8
Authors:Kishan, K.V.R., Newcomer, M.E.
Deposit date:1997-07-07
Release date:1998-07-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The SH3 domain of Eps8 exists as a novel intertwined dimer.
Nat.Struct.Biol., 4, 1997
1AVZ
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V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN
Descriptor:NEGATIVE FACTOR, FYN TYROSINE KINASE
Authors:Arold, S., Franken, P., Dumas, C.
Deposit date:1997-09-23
Release date:1998-03-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
Structure, 5, 1997
1AWJ
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INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:ITK
Authors:Andreotti, A.H., Bunnell, S.C., Feng, S., Berg, L.J., Schreiber, S.L.
Deposit date:1997-10-02
Release date:1998-01-14
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Regulatory intramolecular association in a tyrosine kinase of the Tec family.
Nature, 385, 1997
1AWO
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THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES
Descriptor:ABL TYROSINE KINASE
Authors:Cowburn, D.
Deposit date:1997-10-03
Release date:1998-01-28
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct.
Structure, 3, 1995
1AWW
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SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, 42 STRUCTURES
Descriptor:BRUTON'S TYROSINE KINASE
Authors:Hansson, H., Mattsson, P.T., Allard, P., Haapaniemi, P., Vihinen, M., Smith, C.I.E., Hard, T.
Deposit date:1997-10-06
Release date:1998-04-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain from Bruton's tyrosine kinase.
Biochemistry, 37, 1998
1AWX
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SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:BRUTON'S TYROSINE KINASE
Authors:Hansson, H., Mattsson, P.T., Allard, P., Haapaniemi, P., Vihinen, M., Smith, C.I.E., Hard, T.
Deposit date:1997-10-06
Release date:1998-04-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain from Bruton's tyrosine kinase.
Biochemistry, 37, 1998
1AZE
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NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES
Descriptor:GRB2, SOS
Authors:Vidal, M., Gincel, E., Goudreau, N., Cornille, F., Parker, F., Duchesne, M., Tocque, B., Garbay, C., Roques, B.P.
Deposit date:1997-11-17
Release date:1999-05-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.
J.Mol.Biol., 290, 1999
1AZG
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NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE
Descriptor:PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR, FYN
Authors:Renzoni, D.A., Pugh, D.J.R., Siligardi, G., Das, P., Morton, C.J., Rossi, C., Waterfield, M.D., Campbell, I.D., Ladbury, J.E.
Deposit date:1997-11-18
Release date:1998-02-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.
Biochemistry, 35, 1996
1B07
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CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
Descriptor:PROTEIN (PROTO-ONCOGENE CRK (CRK))
Authors:Nguyen, J.T., Turck, C.W., Cohen, F.E., Zuckermann, R.N., Lim, W.A.
Deposit date:1998-11-17
Release date:1999-01-06
Modification date:2013-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
1BBZ
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CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS
Descriptor:ABL TYROSINE KINASE, PEPTIDE P41
Authors:Pisabarro, M.T., Serrano, L., Wilmanns, M.
Deposit date:1998-04-28
Release date:1998-11-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions.
J.Mol.Biol., 281, 1998
1BU1
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SRC FAMILY KINASE HCK SH3 DOMAIN
Descriptor:PROTEIN (HEMOPOIETIC CELL KINASE) (2.7.1.112)
Authors:Arold, S., Franken, P., Dumas, C.
Deposit date:1998-09-09
Release date:1998-11-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
Biochemistry, 37, 1998
1CKA
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STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK
Descriptor:C-CRK (N-TERMINAL SH3 DOMAIN) (C-CRKSH3-N) COMPLEXED WITH C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG)
Authors:Wu, X., Kuriyan, J.
Deposit date:1995-01-24
Release date:1995-05-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure, 3, 1995
1CKB
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STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK
Descriptor:C-CRK (N-TERMINAL SH3 DOMAIN) (C-CRKSH3-N) COMPLEXED WITH SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG)
Authors:Wu, X., Kuriyan, J.
Deposit date:1995-01-24
Release date:1995-05-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk.
Structure, 3, 1995
1CSK
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THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP
Descriptor:C-SRC KINASE (SH3 DOMAIN) (E.C.2.7.1.112)
Authors:Mathieu, M., Wierenga, R.K.
Deposit date:1994-03-22
Release date:1994-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop.
FEBS Lett., 341, 1994
1EFN
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HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
Descriptor:FYN TYROSINE KINASE, HIV-1 NEF PROTEIN
Authors:Lee, C.-H., Kuriyan, J.
Deposit date:1996-06-29
Release date:1997-01-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996
1FYN
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PHOSPHOTRANSFERASE
Descriptor:PHOSPHOTRANSFERASE FYN, 3BP-2
Authors:Musacchio, A., Saraste, M., Wilmanns, M.
Deposit date:1995-05-17
Release date:1996-11-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
1GBR
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ORIENTATION OF PEPTIDE FRAGMENTS FROM SOS PROTEINS BOUND TO THE N-TERMINAL SH3 DOMAIN OF GRB2 DETERMINED BY NMR SPECTROSCOPY
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2, N-TERMINAL SH3 DOMAIN) COMPLEXED WITH SOS-A PEPTIDE (NMR, 29 STRUCTURES)
Authors:Wittekind, M., Mapelli, C., Farmer, B.T., Suen, K.-L., Goldfarb, V., Tsao, J., Lavoie, T., Barbacid, M., Meyers, C.A., Mueller, L.
Deposit date:1994-08-12
Release date:1995-01-26
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.
Biochemistry, 33, 1994
1GCP
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CRYSTAL STRUCTURE OF VAV SH3 DOMAIN
Descriptor:VAV SH3 DOMAIN
Authors:Nishida, M., Nagata, K., Hachimori, Y., Ogura, K., Inagaki, F.
Deposit date:2000-08-08
Release date:2001-08-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
1GFC
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) (C-TERMINAL SH3 DOMAIN) (NMR, MINIMIZED MEAN STRUCTURE)
Authors:Kohda, D., Terasawa, H., Hatanaka, H., Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GFD
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) (C-TERMINAL SH3 DOMAIN) (NMR, 20 STRUCTURES)
Authors:Kohda, D., Terasawa, H., Hatanaka, H., Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GL5
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NMR STRUCTURE OF THE SH3 DOMAIN FROM THE TEC PROTEIN TYROSINE KINASE
Descriptor:TYROSINE-PROTEIN KINASE TEC (E.C.2.7.1.112)
Authors:Mulhern, T.D., Pursglove, S.E., Booker, G.W.
Deposit date:2001-08-28
Release date:2001-11-28
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The Solution Structure and Intramolecular Associations of the Tec Kinase Src Homology 3 Domain.
J.Biol.Chem., 277, 2002
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