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7JT9	Fgr SH3 domain crystal structure Descriptor: Tyrosine-protein kinase Fgr Authors: Perez, I, Berndt, S, Gurevich, V.V, Iverson, T.M. Deposit date: 2020-08-17 Release date: 2022-01-26 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.93 Å) Cite: A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr. J.Mol.Biol., 434, 2022
6NMW	Crystal structure of the human Lyn SH3 domain Descriptor: Tyrosine-protein kinase Lyn Authors: Berndt, S, Gurevich, V.V, Iverson, T.M. Deposit date: 2019-01-12 Release date: 2019-04-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.199 Å) Cite: Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase. PLoS ONE, 14, 2019
4Y92	Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant Descriptor: GLYCEROL, Protein-tyrosine kinase, SULFATE ION, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2015-02-16 Release date: 2016-03-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain E97T-Q128R mutant to be published
6IPY	His-tagged Fyn SH3 domain R96I mutant Descriptor: Tyrosine-protein kinase Fyn Authors: Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.343 Å) Cite: Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
6IPZ	Fyn SH3 domain R96W mutant, crystallized with 18-crown-6 Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Tyrosine-protein kinase Fyn Authors: Arold, S.T, Aljedani, S.S, Shahul Hameed, U.F. Deposit date: 2018-11-05 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.576 Å) Cite: Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
4ZNX	Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12 Descriptor: APP12, Tyrosine-protein kinase Fyn Authors: Camara-Artigas, A. Deposit date: 2015-05-05 Release date: 2016-06-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase. Acta Crystallogr.,Sect.F, 72, 2016
6EDF	Fragment of a tyrosine-protein kinase Descriptor: FYN, GLYCEROL, UNKNOWN ATOM OR ION Authors: Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-08-09 Release date: 2018-08-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Fragment of a tyrosine-protein kinase To be Published
1CSK	THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP Descriptor: C-SRC SH3 DOMAIN Authors: Mathieu, M, Wierenga, R.K. Deposit date: 1994-03-22 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop. FEBS Lett., 341, 1994
1CKB	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
1CKA	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
6RO9	Human spectrin SH3 domain D48G, E7V, K60V Descriptor: Spectrin alpha, non-erythrocytic 1 Authors: Reverter, D, Navarro, S, Ventura, S. Deposit date: 2019-05-10 Release date: 2020-06-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.814 Å) Cite: Human spectrin SH3 domain D48G, E7V, K60V To Be Published
6SCW	SH3-subunit of chicken alpha spectrin solved by NMR Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11 Authors: Grohe, K, Hebrank, C, Linser, R. Deposit date: 2019-07-25 Release date: 2020-08-12 Last modified: 2024-01-31 Method: SOLUTION NMR Cite: Protein Motional Details Revealed by Complementary Structural Biology Techniques. Structure, 28, 2020
6SDF	N-terminal SH3 domain of Grb2 protein Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2 Authors: Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B. Deposit date: 2019-07-26 Release date: 2020-01-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the SH3 domain of growth factor receptor-bound protein 2. Acta Crystallogr.,Sect.F, 76, 2020
8KDX	Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current Descriptor: Microtubule-associated protein tau, Tyrosine-protein kinase Fyn Authors: Padavattan, S, Jos, S. Deposit date: 2023-08-10 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (1.01 Å) Cite: Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current. J.Mol.Biol., 436, 2024
8WFF	The Crystal Structure of LYN from Biortus. Descriptor: CHLORIDE ION, CITRATE ANION, Tyrosine-protein kinase Lyn Authors: Wang, F, Cheng, W, Yuan, Z, Qi, J, Lu, Y. Deposit date: 2023-09-19 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The Crystal Structure of LYN from Biortus. To Be Published
5UL6	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions Descriptor: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus Authors: Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. Deposit date: 2017-01-24 Release date: 2017-08-09 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.45 Å) Cite: The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus. ACS Chem. Biol., 12, 2017
5VEI	Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 Descriptor: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION Authors: Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2017-04-04 Release date: 2017-08-02 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.33 Å) Cite: Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 To be Published
7NET	Crystal structure of the v-Src SH3 domain W95R-I96T mutant Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ... Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
7NES	Crystal structure of the v-Src SH3 domain N117D-V124L mutant Descriptor: GLYCINE, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2021-06-16 Method: X-RAY DIFFRACTION (1.35 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
7NER	Crystal structure of the v-Src SH3 domain Q128R mutant Descriptor: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
8CF4	SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the combined correction method with PDB 2NUZ Descriptor: Spectrin alpha chain, non-erythrocytic 1 Authors: Soeldner, B. Deposit date: 2023-02-02 Release date: 2023-03-08 Method: SOLID-STATE NMR Cite: Integrated Assessment of the Structure and Dynamics of Solid Proteins. J Phys Chem Lett, 14, 2023
8CHH	SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction method for spin-diffusion with PDB 2NUZ as reference Descriptor: Spectrin alpha chain, non-erythrocytic 1 Authors: Soeldner, B. Deposit date: 2023-02-08 Release date: 2023-03-08 Method: SOLID-STATE NMR Cite: Integrated Assessment of the Structure and Dynamics of Solid Proteins. J Phys Chem Lett, 14, 2023
8CHG	SH3 domain solved by the exact solid-state method from the Bruker Dynamics Center using the correction for dipolar truncation with PDB 2NUZ Descriptor: Spectrin alpha chain, non-erythrocytic 1 Authors: Soeldner, B. Deposit date: 2023-02-08 Release date: 2023-03-08 Method: SOLID-STATE NMR Cite: Integrated Assessment of the Structure and Dynamics of Solid Proteins. J Phys Chem Lett, 14, 2023
7NZC	First SH3 domain of POSH (Plenty of SH3 Domains protein) Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase SH3RF1 Authors: Palencia, A, Bessa, L.M, Jensen, M.R. Deposit date: 2021-03-23 Release date: 2021-12-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.111 Å) Cite: Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
5XGG	Crystal Structure C-terminal SH3 domain of Myosin IB from Entamoeba histolytica Descriptor: SULFATE ION, Unconventional myosin IB Authors: Gautam, G, Gourinath, S. Deposit date: 2017-04-13 Release date: 2017-08-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition Acta Crystallogr D Struct Biol, 73, 2017

 

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