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1G2B
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1g2b
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Berisio, R., Viguera, A.R., Serrano, L., Wilmanns, M.
Deposit date:2000-10-18
Release date:2000-11-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Atomic resolution structure of a mutant of the spectrin SH3 domain.
Acta Crystallogr.,Sect.D, 57, 2001
1JO8
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1jo8
STRUCTURAL ANALYSIS OF THE YEAST ACTIN BINDING PROTEIN ABP1 SH3 DOMAIN
Descriptor:ACTIN BINDING PROTEIN
Authors:Fazi, B., Cope, M.J., Douangamath, A., Ferracuti, S., Schirwitz, K., Zucconi, A., Drubin, D.G., Wilmanns, M., Cesareni, G., Castagnoli, L.
Deposit date:2001-07-27
Release date:2002-03-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis.
J.Biol.Chem., 277, 2002
1TUD
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1tud
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48
Descriptor:ALPHA-SPECTRIN
Authors:Viguera, A.R., Serrano, L., Wilmanns, M.
Deposit date:1996-02-29
Release date:1996-08-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics.
J.Mol.Biol., 247, 1995
1W6X
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1w6x
SH3 DOMAIN OF P40PHOX, COMPONENT OF THE NADPH OXIDASE
Descriptor:NEUTROPHIL CYTOSOL FACTOR 4
Authors:Massenet, C., Chenavas, S., Cohen-Addad, C., Dagher, M.-C., Brandolin, G., Pebay-Peyroula, E., Fieschi, F.
Deposit date:2004-08-24
Release date:2005-01-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains
J.Biol.Chem., 280, 2005
1Z9Q
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1z9q
SOLUTION STRUCTURE OF SH3 DOMAIN OF P40PHOX
Descriptor:Neutrophil cytosol factor 4
Authors:Adachi, S., Ogura, K., Fujioka, Y., Inagaki, F.
Deposit date:2005-04-04
Release date:2006-03-21
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of SH3 domain of p40phox
to be published
2K3B
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2k3b
SEEING THE INVISIBLE: STRUCTURES OF EXCITED PROTEIN STATES BY RELAXATION DISPERSION NMR
Descriptor:Actin-binding protein
Authors:Vallurupalli, P., Hansen, F.D., Kay, L.E.
Deposit date:2008-04-30
Release date:2008-07-29
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy
Proc.Natl.Acad.Sci.Usa, 105, 2008
2KYM
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2kym
SOLUTION STRUCTURE OF THE BEM1P SH3-CI DOMAIN FROM L.ELONGISPORUS IN COMPLEX WITH STE20P PEPTIDE
Descriptor:Bud emergence protein 1, Peptide form Serine/threonine-protein kinase STE20
Authors:Gorelik, M., Muhandiram, R., Davidson, A.R.
Deposit date:2010-06-02
Release date:2010-06-23
Method:SOLUTION NMR
Cite:Structural and functional characterization of an unusual SH3 domain from the fungal scaffold protein, Bem1p
To be Published
2L2P
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2l2p
FOLDING INTERMEDIATE OF THE FYN SH3 A39V/N53P/V55L FROM NMR RELAXATION DISPERSION EXPERIMENTS
Descriptor:Tyrosine-protein kinase Fyn (E.C.2.7.10.2)
Authors:Neudecker, P., Robustelli, P., Cavalli, A., Vendruscolo, M., Kay, L.E.
Deposit date:2010-08-25
Release date:2011-09-14
Modification date:2012-05-16
Method:SOLUTION NMR
Cite:Structure of an intermediate state in protein folding and aggregation.
Science, 336, 2012
2LP5
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2lp5
NATIVE STRUCTURE OF THE FYN SH3 A39V/N53P/V55L
Descriptor:Tyrosine-protein kinase Fyn (E.C.2.7.10.2)
Authors:Neudecker, P., Robustelli, P., Cavalli, A., Vendruscolo, M., Kay, L.E.
Deposit date:2012-02-06
Release date:2012-05-16
Method:SOLUTION NMR
Cite:Structure of an intermediate state in protein folding and aggregation.
Science, 336, 2012
2RPN
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2rpn
A CRUCIAL ROLE FOR HIGH INTRINSIC SPECIFICITY IN THE FUNCTION OF YEAST SH3 DOMAINS
Descriptor:Actin-binding protein, Actin-regulating kinase 1
Authors:Stollar, E.J., Garcia, B., Chong, A., Forman-Kay, J., Davidson, A.
Deposit date:2008-06-12
Release date:2009-06-16
Modification date:2009-10-13
Method:SOLUTION NMR
Cite:Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p
J.Biol.Chem., 284, 2009
2RQV
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2rqv
SOLUTION STRUCTURE OF SH3CI DOMAIN OF BEM1P
Descriptor:Bud emergence protein 1
Authors:Takaku, T., Ogura, K., Inagaki, F.
Deposit date:2009-12-21
Release date:2010-04-21
Modification date:2010-06-23
Method:SOLUTION NMR
Cite:Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
2RQW
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2rqw
SOLUTION STRUCTURE OF BEM1P SH3CI DOMAIN COMPLEXED WITH STE20P-PRR PEPTIDE
Descriptor:Bud emergence protein 1, 24-meric peptide from Serine/threonine-protein kinase STE20
Authors:Takaku, T., Ogura, K., Inagaki, F.
Deposit date:2009-12-21
Release date:2010-04-21
Modification date:2010-06-23
Method:SOLUTION NMR
Cite:Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
3CQT
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3cqt
N53I V55L MUTANT OF FYN SH3 DOMAIN
Descriptor:Proto-oncogene tyrosine-protein kinase Fyn (E.C.2.7.10.2)
Authors:Neculai, A.M., Zarrine-Afsar, A., Howell, P.L., Davidson, A., Chan, H.S.
Deposit date:2008-04-03
Release date:2008-07-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1AEY
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1aey
ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES
Descriptor:ALPHA-SPECTRIN
Authors:Blanco, F.J., Ortiz, A.R., Serrano, L.
Deposit date:1997-03-02
Release date:1997-05-15
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure.
J.Biomol.NMR, 9, 1997
1AOJ
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1aoj
THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER
Descriptor:EPS8
Authors:Kishan, K.V.R., Newcomer, M.E.
Deposit date:1997-07-07
Release date:1998-07-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The SH3 domain of Eps8 exists as a novel intertwined dimer.
Nat.Struct.Biol., 4, 1997
1AZE
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1aze
NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES
Descriptor:GRB2, SOS
Authors:Vidal, M., Gincel, E., Goudreau, N., Cornille, F., Parker, F., Duchesne, M., Tocque, B., Garbay, C., Roques, B.P.
Deposit date:1997-11-17
Release date:1999-05-18
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.
J.Mol.Biol., 290, 1999
1BK2
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1bk2
A-SPECTRIN SH3 DOMAIN D48G MUTANT
Descriptor:A-SPECTRIN
Authors:Martinez, J.C., Pisabarro, M.T., Serrano, L.
Deposit date:1998-07-14
Release date:1999-02-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Obligatory steps in protein folding and the conformational diversity of the transition state.
Nat.Struct.Biol., 5, 1998
1CSK
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1csk
THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP
Descriptor:C-SRC KINASE (SH3 DOMAIN) (E.C.2.7.1.112)
Authors:Mathieu, M., Wierenga, R.K.
Deposit date:1994-03-22
Release date:1994-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop.
FEBS Lett., 341, 1994
1E6G
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1e6g
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Vega, M.C., Serrano, L.
Deposit date:2000-08-15
Release date:2002-05-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E6H
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1e6h
A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Vega, M.C., Serrano, L.
Deposit date:2000-08-17
Release date:2002-05-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E7O
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1e7o
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Vega, M.C., Serrano, L.
Deposit date:2000-08-31
Release date:2003-05-21
Modification date:2011-08-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Thermodynamic and Kinetic Analysis of the Folding Pathway of an SH3 Domain Entropically Stabilised by a Redesigned Hydrophobic Core
J.Mol.Biol., 328, 2003
1GBQ
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1gbq
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor:GRB2, SOS-1
Authors:Wittekind, M., Mapelli, C., Lee, V., Goldfarb, V., Friedrichs, M.S., Meyers, C.A., Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
1GBR
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1gbr
ORIENTATION OF PEPTIDE FRAGMENTS FROM SOS PROTEINS BOUND TO THE N-TERMINAL SH3 DOMAIN OF GRB2 DETERMINED BY NMR SPECTROSCOPY
Descriptor:GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2, N-TERMINAL SH3 DOMAIN) COMPLEXED WITH SOS-A PEPTIDE (NMR, 29 STRUCTURES)
Authors:Wittekind, M., Mapelli, C., Farmer, B.T., Suen, K.-L., Goldfarb, V., Tsao, J., Lavoie, T., Barbacid, M., Meyers, C.A., Mueller, L.
Deposit date:1994-08-12
Release date:1995-01-26
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.
Biochemistry, 33, 1994
1GRI
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1gri
GRB2
Descriptor:GROWTH FACTOR BOUND PROTEIN 2
Authors:Maignan, S., Arnoux, B., Ducruix, A.
Deposit date:1995-02-28
Release date:1996-03-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the mammalian Grb2 adaptor.
Science, 268, 1995
1H8K
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1h8k
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Vega, M.C., Serrano, L.
Deposit date:2001-02-09
Release date:2002-05-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
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