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1A3P
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1a3p
ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
Descriptor:EPIDERMAL GROWTH FACTOR
Authors:Barnham, K., Torres, A., Alewood, D., Alewood, P., Domagala, T., Nice, E., Norton, R.
Deposit date:1998-01-22
Release date:1998-07-29
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
1EGF
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1egf
SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY MINIMIZATION WITH RESTRAINTS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) (NMR, 16 STRUCTURES)
Authors:Montelione, G.T., Wuthrich, K., Scheraga, H.A.
Deposit date:1991-10-01
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry, 31, 1992
1EPG
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1epg
THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 2 SOLUTION (NMR, MINIMIZED MEAN STRUCTURE)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1EPH
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1eph
THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 2 SOLUTION (NMR, 10 STRUCTURES)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1EPI
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1epi
THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 6.8 SOLUTION (NMR, MINIMIZED MEAN STRUCTURE)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1EPJ
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1epj
THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE STRUCTURES OF MOUSE EPIDERMAL GROWTH FACTOR IN ACIDIC AND PHYSIOLOGICAL PH SOLUTIONS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) IN PH 6.8 SOLUTION (NMR, 5 STRUCTURES)
Authors:Kohda, D., Inagaki, F.
Deposit date:1992-03-24
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional nuclear magnetic resonance structures of mouse epidermal growth factor in acidic and physiological pH solutions.
Biochemistry, 31, 1992
1GK5
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1gk5
SOLUTION STRUCTURE THE MEGF/TGFALPHA44-50 CHIMERIC GROWTH FACTOR
Descriptor:MEGF/TGFALPHA44-50 CHIMERA
Authors:Chamberlin, S.G., Brennan, L., Puddicombe, S.M., Davies, D.E., Turner, D.L.
Deposit date:2001-08-08
Release date:2002-08-08
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution Structure of the Megf/Tgfalpha44-50 Chimeric Growth Factor.
Eur.J.Biochem., 268, 2001
1JL9
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1jl9
CRYSTAL STRUCTURE OF HUMAN EPIDERMAL GROWTH FACTOR
Descriptor:EPIDERMAL GROWTH FACTOR
Authors:Lu, H.S., Chai, J.J., Li, M., Huang, B.R., He, C.H., Bi, R.C.
Deposit date:2001-07-16
Release date:2001-10-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human epidermal growth factor and its dimerization
J.Biol.Chem., 276, 2001
1P9J
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1p9j
SOLUTION STRUCTURE AND DYNAMICS OF THE EGF/TGF-ALPHA CHIMERA T1E
Descriptor:chimera of Epidermal growth factor(EGF) and Transforming growth factor alpha (TGF-alpha)
Authors:Wingens, M., Walma, T., Van Ingen, H., Stortelers, C., Van Leeuwen, J.E., Van Zoelen, E.J., Vuister, G.W.
Deposit date:2003-05-12
Release date:2003-10-07
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural Analysis of an Epidermal Growth Factor/Transforming Growth Factor-alpha Chimera with Unique ErbB Binding Specificity.
J.Biol.Chem., 278, 2003
2KV4
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2kv4
EGF
Descriptor:Epidermal growth factor
Authors:Huang, H.W., Mohan, S.K., Yu, C.
Deposit date:2010-03-08
Release date:2011-02-23
Method:SOLUTION NMR
Cite:The NMR solution structure of human epidermal growth factor (hEGF) at physiological pH and its interactions with suramin
Biochem.Biophys.Res.Commun., 402, 2010
3CA7
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3ca7
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE EGF DOMAIN OF SPITZ
Descriptor:Protein spitz
Authors:Klein, D.E., Stayrook, S.E., Lemmon, M.A.
Deposit date:2008-02-19
Release date:2008-05-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for EGFR ligand sequestration by Argos.
Nature, 453, 2008
3EGF
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3egf
SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY MINIMIZATION WITH RESTRAINTS
Descriptor:EPIDERMAL GROWTH FACTOR (EGF) (NMR, 16 STRUCTURES AFTER ENERGY MINIMIZATION)
Authors:Montelione, G.T., Wuthrich, K., Scheraga, H.A.
Deposit date:1992-08-30
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry, 31, 1992
4D90
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4d90
CRYSTAL STRUCTURE OF DEL-1 EGF DOMAINS
Descriptor:EGF-like repeat and discoidin I-like domain-containing protein 3
Authors:Chen, Q., Schurpf, T., Springer, T., Wang, J.
Deposit date:2012-01-11
Release date:2012-05-30
Modification date:2013-01-02
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:The RGD finger of Del-1 is a unique structural feature critical for integrin binding.
Faseb J., 26, 2012
1APO
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1apo
THREE-DIMENSIONAL STRUCTURE OF THE APO FORM OF THE N-TERMINAL EGF-LIKE MODULE OF BLOOD COAGULATION FACTOR X AS DETERMINED BY NMR SPECTROSCOPY AND SIMULATED FOLDING
Descriptor:EGF-LIKE MODULE OF BLOOD COAGULATION FACTOR X (N-TERMINAL, APO FORM) (NMR, 13 STRUCTURES)
Authors:Ullner, M., Selander, M., Persson, E., Stenflo, J., Drakenberg, T., Teleman, O.
Deposit date:1992-04-21
Release date:1994-01-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional structure of the apo form of the N-terminal EGF-like module of blood coagulation factor X as determined by NMR spectroscopy and simulated folding.
Biochemistry, 31, 1992
1BF9
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1bf9
N-TERMINAL EGF-LIKE DOMAIN FROM HUMAN FACTOR VII, NMR, 23 STRUCTURES
Descriptor:FACTOR VII
Authors:Muranyi, A., Finn, B.E., Gippert, G.P., Forsen, S., Stenflo, J., Drakenberg, T.
Deposit date:1998-05-28
Release date:1999-02-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal EGF-like domain from human factor VII.
Biochemistry, 37, 1998
1CCF
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1ccf
HOW AN EPIDERMAL GROWTH FACTOR (EGF)-LIKE DOMAIN BINDS CALCIUM-HIGH RESOLUTION NMR STRUCTURE OF THE CALCIUM FORM OF THE NH2-TERMINAL EGF-LIKE DOMAIN IN COAGULATION FACTOR X
Descriptor:COAGULATION FACTOR X (THE CALCIUM FORM OF THE N-TERMINAL EGF-LIKE MODULE) (NMR, 15 STRUCTURES)
Authors:Selander-Sunnerhagen, M., Ullner, M., Persson, M., Teleman, O., Stenflo, J., Drakenberg, T.
Deposit date:1993-05-19
Release date:1994-05-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X.
J.Biol.Chem., 267, 1992
1EDM
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1edm
EPIDERMAL GROWTH FACTOR-LIKE DOMAIN FROM HUMAN FACTOR IX
Descriptor:FACTOR IX
Authors:Rao, Z., Handford, P., Mayhew, M., Knott, V., Brownlee, G.G., Stuart, D.
Deposit date:1996-03-21
Release date:1996-10-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions.
Cell(Cambridge,Mass.), 82, 1995
1ESL
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1esl
INSIGHT INTO E-SELECTIN(SLASH)LIGAND INTERACTION FROM THE CRYSTAL STRUCTURE AND MUTAGENESIS OF THE LEC(SLASH)EGF DOMAINS
Descriptor:E-SELECTIN (LECTIN AND EGF DOMAINS, RESIDUES 1 - 157) (FORMERLY KNOWN AS ELAM-1)
Authors:Graves, B.J., Crowther, R.L.
Deposit date:1994-06-03
Release date:1994-08-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains.
Nature, 367, 1994
1F7E
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1f7e
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, 20 STRUCTURES
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1F7M
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1f7m
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII, MINIMIZED
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FF7
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1ff7
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, 20 STRUCTURES
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII (FUCOSYLATED)
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FFM
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1ffm
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FACTOR VII (FUCOSYLATED)
Authors:Kao, Y.-H., Lee, G.F., Wang, Y., Starovasnik, M.A., Kelley, R.F., Spellman, M.W., Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1G1T
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1g1t
CRYSTAL STRUCTURE OF E-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH SLEX
Descriptor:E-SELECTIN, SACCHARIDE COMPLEX
Authors:Somers, W.S., Camphausen, R.T.
Deposit date:2000-10-13
Release date:2001-10-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.
Cell(Cambridge,Mass.), 103, 2000
1IXA
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1ixa
THE THREE-DIMENSIONAL STRUCTURE OF THE FIRST EGF-LIKE MODULE OF HUMAN FACTOR IX: COMPARISON WITH EGF AND TGF-A
Descriptor:EGF-LIKE MODULE OF HUMAN FACTOR IX (NMR, MINIMIZED AVERAGE STRUCTURE)
Authors:Baron, M., Norman, D.G., Harvey, T.S., Hanford, P.A., Mayhew, M., Tse, A.G.D., Brownlee, G.G., Campbell, I.D.C.
Deposit date:1991-11-14
Release date:1993-10-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha.
Protein Sci., 1, 1992
1LPG
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1lpg
CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 79.
Descriptor:Coagulation factor X (E.C.3.4.21.6)
Authors:Schreuder, H.A., Brachvogel, V., Liesum, A.
Deposit date:2002-05-08
Release date:2003-05-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa.
J.Med.Chem., 45, 2002
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110071
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