Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8XJO
DownloadVisualize
BU of 8xjo by Molmil
U46619 bound Thromboxane A2 receptor-Gq Protein Complex
Descriptor: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors
To Be Published
8XJN
DownloadVisualize
BU of 8xjn by Molmil
Cloprosetnol bound Thromboxane A2 receptor-Gq Protein Complex
Descriptor: (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors
To Be Published
8XJM
DownloadVisualize
BU of 8xjm by Molmil
Latanoprost acid bound Prostaglandin F2-alpha receptor-Gq Protein Complex
Descriptor: Antibody fragment scFv16, Engineered miniGq, Fusion tag,Prostaglandin F2-alpha receptor,LgBiT, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors
To Be Published
8XJL
DownloadVisualize
BU of 8xjl by Molmil
PGF2-alpha bound Prostaglandin F2-alpha receptor-Gq Protein Complex
Descriptor: (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors
To Be Published
8XJK
DownloadVisualize
BU of 8xjk by Molmil
Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex
Descriptor: (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ...
Authors:Zhang, X, Li, X, Liu, G, Gong, W.
Deposit date:2023-12-21
Release date:2024-02-28
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural basis for ligand recognition and activation of the prostanoid receptors
To Be Published
8XBI
DownloadVisualize
BU of 8xbi by Molmil
Human GPR34 -Gi complex bound to M1, receptor focused
Descriptor: (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Probable G-protein coupled receptor 34
Authors:Kawahara, R, Shihoya, W, Nureki, O.
Deposit date:2023-12-06
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Cryo-EM structure of the Human GPR34-Gi complex bound to S3E-LysoPS
To Be Published
8XBH
DownloadVisualize
BU of 8xbh by Molmil
Human GPR34 -Gi complex bound to M1
Descriptor: (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Kawahara, R, Shihoya, W, Nureki, O.
Deposit date:2023-12-06
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Cryo-EM structure of the Human GPR34-Gi complex bound to S3E-LysoPS
To Be Published
8X64
DownloadVisualize
BU of 8x64 by Molmil
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with desloratadine
Descriptor: Histamine H1 receptor,Soluble cytochrome b562, desloratadine
Authors:Wang, D.D, Guo, Q.
Deposit date:2023-11-20
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
8X63
DownloadVisualize
BU of 8x63 by Molmil
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with mepyramine
Descriptor: Histamine H1 receptor,Soluble cytochrome b562, mepyramine
Authors:Wang, D.D, Guo, Q.
Deposit date:2023-11-20
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
8X5Y
DownloadVisualize
BU of 8x5y by Molmil
CryoEM structure of the histamine H1 receptor-BRIL/Anti BRIL Fab complex with astemizole
Descriptor: 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Histamine H1 receptor,Soluble cytochrome b562
Authors:Wang, D.D, Guo, Q, Tao, Y.Y.
Deposit date:2023-11-20
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
8X5X
DownloadVisualize
BU of 8x5x by Molmil
CryoEM structure of the histamine H1 receptor in apo-form
Descriptor: Histamine H1 receptor,Soluble cytochrome b562
Authors:Wang, D.D, Guo, Q, Tao, Y.Y.
Deposit date:2023-11-20
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular mechanism of antihistamines recognition and regulation of the histamine H 1 receptor.
Nat Commun, 15, 2024
8WW2
DownloadVisualize
BU of 8ww2 by Molmil
GPR3/Gs complex
Descriptor: CHOLESTEROL HEMISUCCINATE, G-protein coupled receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:He, Y, Xiong, Y.
Deposit date:2023-10-24
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Identification of oleic acid as an endogenous ligand of GPR3.
Cell Res., 2024
8WRZ
DownloadVisualize
BU of 8wrz by Molmil
Cry-EM structure of cannabinoid receptor-arrestin 2 complex
Descriptor: (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, Beta-arrestin-1, Soluble cytochrome b562,Cannabinoid receptor 1, ...
Authors:Wang, Y.X, Wang, T, Wu, L.J, Hua, T, Liu, Z.J.
Deposit date:2023-10-16
Release date:2024-02-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of cannabinoid receptor CB1-beta-arrestin complex.
Protein Cell, 15, 2024
8WRB
DownloadVisualize
BU of 8wrb by Molmil
Lysophosphatidylserine receptor GPR34-Gi complex
Descriptor: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Gong, W, Liu, G, Li, X, Wang, Y, Zhang, X.
Deposit date:2023-10-13
Release date:2023-11-08
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174.
Plos Biol., 21, 2023
8WDT
DownloadVisualize
BU of 8wdt by Molmil
Crystal structure of the human adenosine A2A receptor in complex with photoresponsive ligand photoNECA(blue)
Descriptor: (2S,3S,4R,5R)-5-(6-amino-2-((E)-phenyldiazenyl)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide, Adenosine receptor A2a, Antibody Fab fragment heavy chain, ...
Authors:Araya, T, Asada, H, Iwata, S, Im, D.H.
Deposit date:2023-09-16
Release date:2024-01-17
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A 2A receptor.
Biochem.Biophys.Res.Commun., 695, 2023
8WCC
DownloadVisualize
BU of 8wcc by Molmil
Cryo-EM structure of the CHA-bound mTAAR1 complex
Descriptor: CYCLOHEXYLAMMONIUM ION, Trace amine-associated receptor 1
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WCB
DownloadVisualize
BU of 8wcb by Molmil
Cryo-EM structure of the CHA-bound mTAAR1-Gq complex
Descriptor: CYCLOHEXYLAMMONIUM ION, Engineered G-alpha-q subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WCA
DownloadVisualize
BU of 8wca by Molmil
Cryo-EM structure of the PEA-bound hTAAR1-Gs complex
Descriptor: 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC9
DownloadVisualize
BU of 8wc9 by Molmil
Cryo-EM structure of the ZH8651-bound mTAAR1-Gq complex
Descriptor: 2-(4-bromophenyl)ethanamine, Engineered G-alpha-q subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC8
DownloadVisualize
BU of 8wc8 by Molmil
Cryo-EM structure of the ZH8651-bound hTAAR1-Gs complex
Descriptor: 2-(4-bromophenyl)ethanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC7
DownloadVisualize
BU of 8wc7 by Molmil
Cryo-EM structure of the ZH8667-bound mTAAR1-Gs complex
Descriptor: 2-[4-(3-fluorophenyl)phenyl]ethanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC6
DownloadVisualize
BU of 8wc6 by Molmil
Cryo-EM structure of the PEA-bound mTAAR1-Gs complex
Descriptor: 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC5
DownloadVisualize
BU of 8wc5 by Molmil
Cryo-EM structure of the TMA-bound mTAAR1-Gs complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC4
DownloadVisualize
BU of 8wc4 by Molmil
Cryo-EM structure of the ZH8651-bound mTAAR1-Gs complex
Descriptor: 2-(4-bromophenyl)ethanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023
8WC3
DownloadVisualize
BU of 8wc3 by Molmil
Cryo-EM structure of the SEP363856-bound mTAAR1-Gs complex
Descriptor: 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Rong, N.K, Guo, L.L, Zhang, M.H, Li, Q, Yang, F, Sun, J.P.
Deposit date:2023-09-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Cell, 186, 2023

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon