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1HLL
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1hll
NMR STRUCTURE OF T3-I2, A 32 RESIDUE PEPTIDE FROM THE ALPHA-2A ADRENERGIC RECEPTOR
Descriptor:ALPHA-2A ADRENERGIC RECEPTOR
Authors:Chung, D.A., Zuiderweg, E.R.P., Neubig, R.R.
Deposit date:2000-12-01
Release date:2002-04-10
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix.
Biochemistry, 41, 2002
1HO9
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1ho9
BEST 20 NMR CONFORMERS OF D130I MUTANT T3-I2, A 32 RESIDUE PEPTIDE FROM THE ALPHA 2A ADRENERGIC RECEPTOR
Descriptor:ALPHA-2A ADRENERGIC RECEPTOR
Authors:Chung, D.A., Zuiderweg, E.R., Neubig, R.R.
Deposit date:2000-12-10
Release date:2002-07-24
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix.
Biochemistry, 41, 2002
1HOD
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1hod
NMR STRUCTURE OF D130I MUTANT T3-I2, A 32 RESIDUE PEPTIDE FROM THE ALPHA 2A ADRENERGIC RECEPTOR
Descriptor:ALPHA-2A ADRENERGIC RECEPTOR
Authors:Chung, D.A., Zuiderweg, E.R., Neubig, R.R.
Deposit date:2000-12-10
Release date:2002-07-24
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix.
Biochemistry, 41, 2002
1HOF
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1hof
NMR STRUCTURE OF T3-I2, A 32 RESIDUE PEPTIDE FROM THE ALPHA-2A ADRENERGIC RECEPTOR
Descriptor:ALPHA-2A ADRENERGIC RECEPTOR
Authors:Chung, D.A., Zuiderweg, E.R., Neubig, R.R.
Deposit date:2000-12-10
Release date:2002-07-24
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix.
Biochemistry, 41, 2002
2LNL
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2lnl
STRUCTURE OF HUMAN CXCR1 IN PHOSPHOLIPID BILAYERS
Descriptor:C-X-C chemokine receptor type 1
Authors:Park, S., Das, B.B., Casagrande, F., Nothnagel, H., Chu, M., Kiefer, H., Maier, K., De Angelis, A., Marassi, F.M., Opella, S.J.
Deposit date:2011-12-31
Release date:2012-10-17
Modification date:2012-12-05
Method:SOLID-STATE NMR
Cite:Structure of the chemokine receptor CXCR1 in phospholipid bilayers.
Nature, 491, 2012
3ZEV
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3zev
STRUCTURE OF THERMOSTABLE AGONIST-BOUND NEUROTENSIN RECEPTOR 1 MUTANT WITHOUT LYSOZYME FUSION
Descriptor:NEUROTENSIN RECEPTOR 1 TM86V
Authors:Egloff, P., Hillenbrand, M., Schlinkmann, K.M., Batyuk, A., Mittl, P., Plueckthun, A.
Deposit date:2012-12-07
Release date:2014-01-29
Modification date:2014-02-26
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
4BUO
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4buo
HIGH RESOLUTION STRUCTURE OF THERMOSTABLE AGONIST-BOUND NEUROTENSIN RECEPTOR 1 MUTANT WITHOUT LYSOZYME FUSION
Descriptor:NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
Authors:Egloff, P., Hillenbrand, M., Schlinkmann, K.M., Batyuk, A., Mittl, P., Plueckthun, A.
Deposit date:2013-06-21
Release date:2014-01-29
Modification date:2014-02-26
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
2KS9
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2ks9
SOLUTION CONFORMATION OF SUBSTANCE P IN WATER COMPLEXED WITH NK1R
Descriptor:Substance-P receptor, Substance P
Authors:Gayen, A., Mukhopadhyay, C.
Deposit date:2009-12-31
Release date:2010-11-03
Modification date:2010-11-17
Method:SOLUTION NMR
Cite:NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles
Biochim.Biophys.Acta, 2010
2KSA
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2ksa
SUBSTANCE P IN DMPC/CHAPS ISOTROPIC Q=0.25 BICELLES AS A LIGAND FOR NK1R
Descriptor:Substance-P receptor, Substance P
Authors:Gayen, A., Mukhopadhyay, C.
Deposit date:2009-12-31
Release date:2010-11-03
Modification date:2010-11-17
Method:SOLUTION NMR
Cite:NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles
Biochim.Biophys.Acta, 2010
2KSB
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2ksb
SUBSTANCE P IN ISOTROPIC Q=0.25 DMPC/CHAPS/GM1 BICELLES AS A LIGAND FOR NK1R
Descriptor:Substance-P receptor, Substance P
Authors:Gayen, A., Mukhopadhyay, C.
Deposit date:2009-12-31
Release date:2010-11-03
Modification date:2010-11-17
Method:SOLUTION NMR
Cite:NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles
Biochim.Biophys.Acta, 2010
3RZE
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3rze
STRUCTURE OF THE HUMAN HISTAMINE H1 RECEPTOR IN COMPLEX WITH DOXEPIN
Descriptor:Histamine H1 receptor/Lysozyme chimera
Authors:Shimamura, T., Han, G.W., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Kobayashi, T., Stevens, R., Iwata, S., GPCR Network (GPCR), Joint Center for Innovative Membrane Protein Technologies (JCIMPT)
Deposit date:2011-05-11
Release date:2011-06-15
Modification date:2011-07-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
3UON
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3uon
STRUCTURE OF THE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO AN ANTAGONIST
Descriptor:Human M2 muscarinic acetylcholine receptor T4, lysozyme fusion protein
Authors:Haga, K., Kruse, A.C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., Weis, W.I., Okada, T., Kobilka, B.K., Haga, T., Kobayashi, T.
Deposit date:2011-11-16
Release date:2012-02-01
Modification date:2012-03-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Nature, 482, 2012
3V2W
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3v2w
CRYSTAL STRUCTURE OF A LIPID G PROTEIN-COUPLED RECEPTOR AT 3.35A
Descriptor:Sphingosine 1-phosphate receptor 1, Lysozyme chimera (E.C.3.2.1.17)
Authors:Hanson, M.A., Roth, C.B., Jo, E., Griffith, M.T., Scott, F.L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S.M., Schuerer, S.C., Sanna, M.G., Han, G.W., Kuhn, P., Rosen, H., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2011-12-12
Release date:2012-02-15
Modification date:2012-03-14
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Crystal structure of a lipid G protein-coupled receptor.
Science, 335, 2012
3V2Y
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3v2y
CRYSTAL STRUCTURE OF A LIPID G PROTEIN-COUPLED RECEPTOR AT 2.80A
Descriptor:Sphingosine 1-phosphate receptor 1, Lysozyme chimera (E.C.3.2.1.17)
Authors:Hanson, M.A., Roth, C.B., Jo, E., Griffith, M.T., Scott, F.L., Reinhart, G., Desale, H., Clemons, B., Cahalan, S.M., Schuerer, S.C., Sanna, M.G., Han, G.W., Kuhn, P., Rosen, H., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2011-12-12
Release date:2012-02-15
Modification date:2012-03-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a lipid G protein-coupled receptor.
Science, 335, 2012
3VW7
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3vw7
CRYSTAL STRUCTURE OF HUMAN PROTEASE-ACTIVATED RECEPTOR 1 (PAR1) BOUND WITH ANTAGONIST VORAPAXAR AT 2.2 ANGSTROM
Descriptor:Chimera of Proteinase-activated receptor 1, Lysozyme (E.C.3.2.1.17)
Authors:Zhang, C., Srinivasan, Y., Arlow, D.H., Fung, J.J., Palmer, D., Zheng, Y., Green, H.F., Pandey, A., Dror, R.O., Shaw, D.E., Weis, W.I., Coughlin, S.R., Kobilka, B.K.
Deposit date:2012-08-07
Release date:2012-12-12
Modification date:2013-08-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-resolution crystal structure of human protease-activated receptor 1
Nature, 492, 2012
4DKL
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4dkl
CRYSTAL STRUCTURE OF THE MU-OPIOID RECEPTOR BOUND TO A MORPHINAN ANTAGONIST
Descriptor:Mu-type opioid receptor, lysozyme chimera (E.C.3.2.1.17)
Authors:Manglik, A., Kruse, A.C., Kobilka, T.S., Thian, F.S., Mathiesen, J.M., Sunahara, R.K., Pardo, L., Weis, W.I., Kobilka, B.K., Granier, S.
Deposit date:2012-02-03
Release date:2012-03-21
Modification date:2012-05-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
Nature, 485, 2012
4GRV
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4grv
THE CRYSTAL STRUCTURE OF THE NEUROTENSIN RECEPTOR NTS1 IN COMPLEX WITH NEUROTENSIN (8-13)
Descriptor:Neurotensin receptor type 1, Neurotensin 8-13
Authors:Noinaj, N., White, J.F., Shibata, Y., Love, J., Kloss, B., Xu, F., Gvozdenovic-Jeremic, J., Shah, P., Shiloach, J., Tate, C.G., Grisshammer, R.
Deposit date:2012-08-27
Release date:2012-10-17
Modification date:2012-11-07
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structure of the agonist-bound neurotensin receptor.
Nature, 490, 2012
4MQS
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4mqs
STRUCTURE OF ACTIVE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO THE AGONIST IPEROXO
Descriptor:Muscarinic acetylcholine receptor M2, Nanobody 9-8
Authors:Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K.
Deposit date:2013-09-16
Release date:2013-11-27
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
4MQT
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4mqt
STRUCTURE OF ACTIVE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO THE AGONIST IPEROXO AND ALLOSTERIC MODULATOR LY2119620
Descriptor:Muscarinic acetylcholine receptor M2, Nanobody 9-8
Authors:Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K.
Deposit date:2013-09-16
Release date:2013-11-27
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
4NTJ
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4ntj
STRUCTURE OF THE HUMAN P2Y12 RECEPTOR IN COMPLEX WITH AN ANTITHROMBOTIC DRUG
Descriptor:P2Y purinoceptor 12, Soluble cytochrome b562
Authors:Zhang, K., Zhang, J., Gao, Z.-G., Zhang, D., Zhu, L., Han, G.W., Moss, S.M., Paoletta, S., Kiselev, E., Lu, W., Fenalti, G., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2013-12-02
Release date:2014-03-26
Modification date:2014-05-28
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of the human P2Y12 receptor in complex with an antithrombotic drug
Nature, 509, 2014
4PXZ
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4pxz
CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESADP
Descriptor:P2Y purinoceptor 12, Soluble cytochrome b562
Authors:Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2014-03-25
Release date:2014-04-30
Modification date:2014-09-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
4PY0
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4py0
CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESATP
Descriptor:P2Y purinoceptor 12, Soluble cytochrome b562
Authors:Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR)
Deposit date:2014-03-25
Release date:2014-04-30
Modification date:2014-09-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
1F88
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1f88
CRYSTAL STRUCTURE OF BOVINE RHODOPSIN
Descriptor:RHODOPSIN
Authors:Okada, T., Palczewski, K., Stenkamp, R.E., Miyano, M.
Deposit date:2000-06-29
Release date:2000-08-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of rhodopsin: A G protein-coupled receptor.
Science, 289, 2000
1GZM
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1gzm
STRUCTURE OF BOVINE RHODOPSIN IN A TRIGONAL CRYSTAL FORM
Descriptor:RHODOPSIN
Authors:Li, J.
Deposit date:2002-05-24
Release date:2003-11-20
Modification date:2011-10-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of Bovine Rhodopsin in a Trigonal Crystal Form
J.Mol.Biol., 343, 2004
1HZX
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1hzx
CRYSTAL STRUCTURE OF BOVINE RHODOPSIN
Descriptor:RHODOPSIN
Authors:Teller, D.C., Okada, T., Behnke, C.A., Palczewski, K., Stenkamp, R.E.
Deposit date:2001-01-26
Release date:2001-07-04
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
Biochemistry, 40, 2001
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entries available on 2014-09-17
00:00 UTC / 09:00 JST