PDB: 43 resultsInfo pagesStatus searchChemie searchBIRD

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5K2Z	PDX1.3-adduct (Arabidopsis) Descriptor: 1,2-ETHANEDIOL, 2-azanylpenta-1,4-dien-3-one, CHLORIDE ION, ... Authors: Robinson, G.C, Kaufmann, M, Roux, C, Fitzpatrick, T.B. Deposit date: 2016-05-19 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural definition of the lysine swing in Arabidopsis thaliana PDX1: Intermediate channeling facilitating vitamin B6 biosynthesis. Proc.Natl.Acad.Sci.USA, 113, 2016
6F8G	Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment Descriptor: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein Authors: Ostertag, M.S, Popowicz, G.M, Sattler, M. Deposit date: 2017-12-13 Release date: 2018-11-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.03 Å) Cite: The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation. Structure, 27, 2019
6F8F	Co-crystal structure of SPOP MATH domain and human Pdx1 fragment Descriptor: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein Authors: Ostertag, M.S, Popowicz, G.M, Sattler, M. Deposit date: 2017-12-13 Release date: 2018-11-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation. Structure, 27, 2019
6HYE	PDX1.2/PDX1.3 complex (PDX1.3:K97A) Descriptor: Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2, SULFATE ION Authors: Robinson, G.C, Kaufmann, M, Roux, C, Martinez-Font, J, Hothorn, M, Thore, S, Fitzpatrick, T.B. Deposit date: 2018-10-20 Release date: 2019-04-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3: a total eclipse. Acta Crystallogr D Struct Biol, 75, 2019
6HXG	PDX1.2/PDX1.3 complex (intermediate) Descriptor: Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2, SULFATE ION Authors: Robinson, G.C, Kaufmann, M, Roux, C, Martinez-Font, J, Hothorn, M, Thore, S, Fitzpatrick, T.B. Deposit date: 2018-10-17 Release date: 2019-04-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3: a total eclipse. Acta Crystallogr D Struct Biol, 75, 2019
6HX3	PDX1.2/PDX1.3 complex Descriptor: Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2, SULFATE ION Authors: Robinson, G.C, Kaufmann, M, Roux, C, Martinez-Font, J, Hothorn, M, Thore, S, Fitzpatrick, T.B. Deposit date: 2018-10-15 Release date: 2019-04-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3: a total eclipse. Acta Crystallogr D Struct Biol, 75, 2019
5K3V	apo-PDX1.3 (Arabidopsis) Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... Authors: Robinson, G.C, Kaufmann, M, Roux, C, Fitzpatrick, T.B. Deposit date: 2016-05-20 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural definition of the lysine swing in Arabidopsis thaliana PDX1: Intermediate channeling facilitating vitamin B6 biosynthesis. Proc.Natl.Acad.Sci.USA, 113, 2016
3FEM	Structure of the synthase subunit Pdx1.1 (Snz1) of PLP synthase from Saccharomyces cerevisiae Descriptor: Pyridoxine biosynthesis protein SNZ1 Authors: Strohmeier, M, Windeisen, V, Sinning, I, Tews, I. Deposit date: 2008-11-30 Release date: 2009-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3.02 Å) Cite: X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases. Febs Lett., 583, 2009
2H1K	Crystal structure of the Pdx1 homeodomain in complex with DNA Descriptor: 15-mer DNA, Pancreatic and duodenal homeobox 1 Authors: Longo, A, Guanga, G.P, Rose, R.B. Deposit date: 2006-05-16 Release date: 2007-03-20 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Structural basis for induced fit mechanisms in DNA recognition by the pdx1 homeodomain Biochemistry, 46, 2007
4ADS	Crystal structure of plasmodial PLP synthase complex Descriptor: PDX2 PROTEIN, PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, ... Authors: Guedez, G, Sinning, I, Tews, I. Deposit date: 2012-01-03 Release date: 2012-01-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.61 Å) Cite: Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
4ADT	Crystal structure of plasmodial PLP synthase Descriptor: PHOSPHATE ION, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE Authors: Guedez, G, Sinning, I, Tews, I. Deposit date: 2012-01-03 Release date: 2012-01-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
4ADU	Crystal structure of plasmodial PLP synthase with bound R5P intermediate Descriptor: 1,2-ETHANEDIOL, PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE, ... Authors: Guedez, G, Sinning, I, Tews, I. Deposit date: 2012-01-03 Release date: 2012-01-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Assembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme. Structure, 20, 2012
7NHF	Crystal structure of Arabidopsis thaliana Pdx1K166R Descriptor: PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3 Authors: Rodrigues, M.J, Zhang, Y, Bolton, R, Evans, G, Giri, N, Royant, A, Begley, T, Ealick, S.E, Tews, I. Deposit date: 2021-02-10 Release date: 2021-12-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Trapping and structural characterisation of a covalent intermediate in vitamin B 6 biosynthesis catalysed by the Pdx1 PLP synthase. Rsc Chem Biol, 3, 2022
7NHE	Crystal structure of Arabidopsis thaliana Pdx1K166R-I333 complex Descriptor: PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, [(~{E},4~{S})-4-azanyl-3-oxidanylidene-pent-1-enyl] dihydrogen phosphate Authors: Rodrigues, M.J, Zhang, Y, Bolton, R, Evans, G, Giri, N, Royant, A, Begley, T, Ealick, S.E, Tews, I. Deposit date: 2021-02-10 Release date: 2021-12-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Trapping and structural characterisation of a covalent intermediate in vitamin B 6 biosynthesis catalysed by the Pdx1 PLP synthase. Rsc Chem Biol, 3, 2022
7KPK	Crystal structure of the SPOP MATH domain in complex with a fragment of Pdx1 Descriptor: Pdx1 peptide, Speckle-type POZ protein Authors: Usher, E.T, Boal, A.K. Deposit date: 2020-11-11 Release date: 2021-04-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity. J.Biol.Chem., 296, 2021
7LB6	PDX1.2/PDX1.3 co-expression complex Descriptor: Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 Authors: Novikova, I.V, Evans, J.E. Deposit date: 2021-01-07 Release date: 2021-09-22 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. Acs Chem.Biol., 16, 2021
7LB5	Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 (Arabidopsis thaliana) Descriptor: Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 Authors: Novikova, I.V, Evans, J.E. Deposit date: 2021-01-07 Release date: 2021-09-22 Last modified: 2021-12-01 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. Acs Chem.Biol., 16, 2021
8S2X	SSX structure of Arabidopsis thaliana Pdx1.3 grown in microfluidic droplets Descriptor: CITRIC ACID, PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3 Authors: Stubbs, J, Tews, I, Maly, M. Deposit date: 2024-02-19 Release date: 2024-02-28 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Droplet microfluidics for time-resolved serial crystallography. Iucrj, 11, 2024
8S2W	SSX structure of Arabidopsis thaliana Pdx1.3 grown in seeded batch conditions Descriptor: PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3 Authors: Stubbs, J, Tews, I, Maly, M. Deposit date: 2024-02-19 Release date: 2024-02-28 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Droplet microfluidics for time-resolved serial crystallography. Iucrj, 11, 2024
5LNS	Crystal structure of Arabidopsis thaliana Pdx1-R5P complex Descriptor: PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, RIBULOSE-5-PHOSPHATE Authors: Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. Deposit date: 2016-08-06 Release date: 2017-01-18 Last modified: 2017-02-22 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
5LNU	Crystal structure of Arabidopsis thaliana Pdx1-I320 complex Descriptor: (4~{S})-4-azanyl-5-oxidanyl-pent-1-en-3-one, PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... Authors: Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. Deposit date: 2016-08-06 Release date: 2017-01-18 Last modified: 2017-02-22 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
5LNR	Crystal structure of Arabidopsis thaliana Pdx1-PLP complex Descriptor: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal 5'-phosphate synthase subunit PDX1.3 Authors: Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. Deposit date: 2016-08-06 Release date: 2017-01-18 Last modified: 2017-02-22 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
5LNW	Crystal structure of Arabidopsis thaliana Pdx1-I320-G3P complex Descriptor: 5-O-phosphono-beta-D-ribofuranose, GLYCEROL, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... Authors: Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. Deposit date: 2016-08-06 Release date: 2017-01-18 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
5LNV	Crystal structure of Arabidopsis thaliana Pdx1-I320 complex from multiple crystals Descriptor: (4~{S})-4-azanyl-5-oxidanyl-pent-1-en-3-one, PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PDX1.3, ... Authors: Rodrigues, M.J, Windeisen, V, Zhang, Y, Guedez, G, Weber, S, Strohmeier, M, Hanes, J.W, Royant, A, Evans, G, Sinning, I, Ealick, S.E, Begley, T.P, Tews, I. Deposit date: 2016-08-06 Release date: 2017-01-18 Last modified: 2018-09-19 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nat. Chem. Biol., 13, 2017
2NV2	Structure of the PLP synthase complex Pdx1/2 (YaaD/E) from Bacillus subtilis Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLUTAMINE, ... Authors: Strohmeier, M, Tews, I, Sinning, I. Deposit date: 2006-11-10 Release date: 2006-12-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structure of a bacterial pyridoxal 5'-phosphate synthase complex Proc.Natl.Acad.Sci.Usa, 103, 2006

 

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