PDB: 11 resultsInfo pagesStatus searchChemie searchBIRD

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1GA5	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT Descriptor: 5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*(5IT)P*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ... Authors: Sierk, M.L, Zhao, Q, Rastinejad, F. Deposit date: 2000-11-29 Release date: 2001-11-16 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: DNA Deformability as a Recognition Feature in the RevErb Response Element Biochemistry, 40, 2001
1A6Y	REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX Descriptor: DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), ORPHAN NUCLEAR RECEPTOR NR1D1, ... Authors: Zhao, Q, Khorasanizadeh, S, Rastinejad, F. Deposit date: 1998-03-04 Release date: 1998-10-21 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural elements of an orphan nuclear receptor-DNA complex. Mol.Cell, 1, 1998
1HLZ	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT Descriptor: 5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ... Authors: Sierk, M.L, Zhao, Q, Rastinejad, F. Deposit date: 2000-12-04 Release date: 2001-11-16 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: DNA Deformability as a Recognition Feature in the RevErb Response Element Biochemistry, 40, 2001
3N00	Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A Descriptor: Nuclear receptor corepressor 1, Rev-erbA-alpha Authors: Gampe, R, Nolte, R. Deposit date: 2010-05-13 Release date: 2010-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction. Nat.Struct.Mol.Biol., 17, 2010
8D8I	Crystal structure of Reverb alpha in complex with synthetic agonist Descriptor: (4S)-6-[([1,1'-biphenyl]-2-yl)oxy]-3-chloro[1,2,4]triazolo[4,3-b]pyridazine, Nuclear receptor corepressor 1, Nuclear receptor subfamily 1 group D member 1 Authors: Ronin, C, Ciesielski, F, Hegazy, L, Burris, P.T. Deposit date: 2022-06-08 Release date: 2022-12-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.504 Å) Cite: Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB. Nat Commun, 13, 2022
4CN5	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Nr1d1 Response Element Descriptor: 5'-D(*AP*TP*TP*GP*AP*AP*CP*TP*CP*TP*GP*AP*CP*CP *CP*CP*AP)-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*AP*GP*AP*GP*TP*TP*CP *AP*AP*TP)-3', CHLORIDE ION, ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
6WMS	Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID2 Peptide Descriptor: NCOR isoform c, Nuclear receptor Rev-ErbA beta variant 1, PROTOPORPHYRIN IX CONTAINING FE Authors: Mosure, S.A, Shang, J, Kojetin, D.J. Deposit date: 2020-04-21 Release date: 2021-02-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta. Sci Adv, 7, 2021
6WMQ	Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID1 Peptide Descriptor: Nuclear receptor Rev-ErbA beta variant 1, Nuclear receptor corepressor 1, PROTOPORPHYRIN IX CONTAINING FE Authors: Mosure, S.A, Shang, J, Kojetin, D.J. Deposit date: 2020-04-21 Release date: 2021-02-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta. Sci Adv, 7, 2021
4CN3	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Gde1SpA Response Element Descriptor: 5'-D(*CP*TP*AP*GP*TP*TP*CP*AP*AP*AP*GP*TP*TP*CP *AP*CP*A)-3', 5'-D(*TP*GP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*AP*CP *TP*AP*G)-3', RETINOIC ACID RECEPTOR RXR-ALPHA, ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4CN2	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*TP*TP*GP*AP*CP*CP*CP*TP*TP*GP*AP*AP*DC *TP*CP*AP)-3', 5'-D(*TP*GP*AP*GP*TP*TP*CP*AP*AP*GP*GP*GP*TP*DC *AP*AP*TP)-3', ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.069 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4CN7	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to an idealized DR1 Response Element Descriptor: 5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP *AP*GP)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP *AP*GP)-3', CHLORIDE ION, ... Authors: McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. Deposit date: 2014-01-21 Release date: 2015-02-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015