4WAA
| Crystal structure of Nix LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | Deposit date: | 2014-08-29 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins. Sci Rep, 7, 2017
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5GMV
| LC3B-FUNDC1 complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1 | Authors: | Lv, M, Wang, C, Li, F. | Deposit date: | 2016-07-17 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy Protein Cell, 8, 2017
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7ELG
| LC3B modificated with a covalent probe | Descriptor: | 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Fan, S, Wan, W. | Deposit date: | 2021-04-10 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6HOG
| Structure of VPS34 LIR motif bound to GABARAP | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, ... | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | Deposit date: | 2018-09-17 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
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6HOK
| Structure of Beclin1 LIR (S96E) motif bound to GABARAP | Descriptor: | 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | Deposit date: | 2018-09-17 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
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5MS2
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5MS6
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5MS5
| Low-salt structure of RavZ LIR2-fused human LC3B | Descriptor: | GLYCEROL, RavZ,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Pantoom, S, Vetter, I.R, Wu, Y.W. | Deposit date: | 2016-12-31 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins. Elife, 6, 2017
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2K6Q
| LC3 p62 complex structure | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, p62_peptide from Sequestosome-1 | Authors: | Noda, N, Kumeta, H, Nakatogawa, H, Satoo, K, Adachi, W, Ishii, J, Fujioka, Y, Ohsumi, Y, Inagaki, F. | Deposit date: | 2008-07-17 | Release date: | 2008-09-02 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis of target recognition by ATG8/LC3 during selective autophagy To be Published
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5CX3
| Crystal structure of FYCO1 LIR in complex with LC3A | Descriptor: | FYVE and coiled-coil domain-containing protein 1, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3A | Authors: | Cheng, X, Pan, L. | Deposit date: | 2015-07-28 | Release date: | 2016-08-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins. Autophagy, 12, 2016
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5D94
| Crystal structure of LC3-LIR peptide complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FYVE and coiled-coil domain-containing protein 1 | Authors: | Takagi, K, Mizushima, T, Johansen, T. | Deposit date: | 2015-08-18 | Release date: | 2015-10-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy J.Biol.Chem., 290, 2015
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5DCN
| Crystal structure of LC3 in complex with TECPR2 LIR | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Stadel, D, Huber, J, Dotsch, V, Rogov, V.V, Behrends, C, Akutsu, M. | Deposit date: | 2015-08-24 | Release date: | 2016-03-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export. Mol.Cell, 60, 2015
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2LUE
| LC3B OPTN-LIR Ptot complex structure | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Optineurin | Authors: | Rogov, V.V, Rozenknop, A, Loehr, F, Guentert, P, Doetsch, V. | Deposit date: | 2012-06-13 | Release date: | 2013-07-17 | Last modified: | 2022-08-24 | Method: | SOLUTION NMR | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella. Biochem.J., 454, 2013
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2N9X
| LC3 FUNDC1 complex structure | Descriptor: | FUN14 domain-containing protein 1, Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Xia, B, Kuang, Y. | Deposit date: | 2015-12-14 | Release date: | 2016-12-14 | Last modified: | 2017-06-07 | Method: | SOLUTION NMR | Cite: | Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy. Autophagy, 12, 2016
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3VTW
| Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 | Descriptor: | Optineurin, microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
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3VTU
| Crystal structure of human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
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3VTV
| Crystal structure of Optineurin LIR-fused human LC3B_2-119 | Descriptor: | Optineurin, microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
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3WAO
| Crystal structure of Atg13 LIR-fused human LC3B_2-119 | Descriptor: | Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | Deposit date: | 2013-05-06 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism. Structure, 22, 2014
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3X0W
| Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, McEwan, D.G, Popovic, D, Gubas, A, Terawaki, S, Stadel, D, Coxon, F, Stegmann, D.M, Bhogaraju, S, Maddi, K, Kirchhoff, A, Gatti, E, Helfrich, M.H, Behrends, C, Pierre, P, Dikic, I, Wakatsuki, S. | Deposit date: | 2014-10-22 | Release date: | 2015-01-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Mol.Cell, 57, 2015
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6HOJ
| Structure of Beclin1 LIR motif bound to GABARAP | Descriptor: | 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | Deposit date: | 2018-09-17 | Release date: | 2019-02-27 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
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6HOL
| Structure of ATG14 LIR motif bound to GABARAPL1 | Descriptor: | Beclin 1-associated autophagy-related key regulator, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1, ... | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | Deposit date: | 2018-09-17 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
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6HOI
| Structure of Beclin1 LIR motif bound to GABARAPL1 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Beclin-1, ... | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | Deposit date: | 2018-09-17 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
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6HOH
| Structure of VPS34 LIR motif (S249E) bound to GABARAP | Descriptor: | Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, TRIETHYLENE GLYCOL | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | Deposit date: | 2018-09-17 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy, 15, 2019
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6J04
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6LAN
| Structure of CCDC50 and LC3B complex | Descriptor: | Coiled-coil domain-containing protein 50,Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Liu, L, Li, J, Hou, P. | Deposit date: | 2019-11-12 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection. Cell Res., 31, 2021
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