PDB: 718 resultsInfo pagesStatus searchChemie searchBIRD

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7K7Y	Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9 Descriptor: Botulinum neurotoxin type E, JLE-E9 Authors: Lam, K, Jin, R. Deposit date: 2020-09-24 Release date: 2020-10-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells. Toxins, 12, 2020
7K84	Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E5 Descriptor: Botulinum neurotoxin type E, JLE-E5, SULFATE ION, ... Authors: Lam, K, Jin, R. Deposit date: 2020-09-25 Release date: 2020-10-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells. Toxins, 12, 2020
4ZBM	Crystal structure of Drosophila cyclic nucleotide gated channel pore mimicking NaK mutant Descriptor: BARIUM ION, POTASSIUM ION, Potassium channel protein Authors: Lam, Y, Zeng, W, Derebe, M.G, Jiang, Y. Deposit date: 2015-04-14 Release date: 2015-07-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels. J.Gen.Physiol., 146, 2015
4FQ0	Crystal structure of FliG-FliM complex from H. pylori Descriptor: Flagellar motor switch protein Authors: Lam, K.H, Au, S.W.N. Deposit date: 2012-06-24 Release date: 2013-05-08 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.82 Å) Cite: Structural basis of FliG-FliM interaction in Helicobacter pylori Mol.Microbiol., 88, 2013
4GC8	Crystal structure of FliM middle domain from H. pylori Descriptor: Flagellar motor switch protein Authors: Lam, K.H, Au, S.W.N. Deposit date: 2012-07-30 Release date: 2013-05-08 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis of FliG-FliM interaction in Helicobacter pylori Mol.Microbiol., 88, 2013
8QZC	Structure of calcium-bound mTMEM16A(ac)-L647V/I733V chloride channel at 3.29 A resolution Descriptor: Anoctamin-1, CALCIUM ION Authors: Lam, A.K.M, Dutzler, R. Deposit date: 2023-10-26 Release date: 2023-12-06 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Mechanistic basis of ligand efficacy in the calcium-activated chloride channel TMEM16A. Embo J., 42, 2023
3E2I	Crystal structure of Thymidine Kinase from S. aureus Descriptor: GLYCEROL, Thymidine kinase, ZINC ION Authors: Lam, R, Johns, K, Battaile, K.P, Romanov, V, Lam, K, Pai, E.F, Chirgadze, N.Y. Deposit date: 2008-08-05 Release date: 2009-08-11 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Crystal structure of Thymidine Kinase from S. aureus To be Published
7ZK3	Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution Descriptor: 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION Authors: Lam, A.K.M, Rutz, S, Dutzler, R. Deposit date: 2022-04-12 Release date: 2022-05-25 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC. Nat Commun, 13, 2022
2W4P	Human common-type acylphosphatase variant, A99G Descriptor: ACYLPHOSPHATASE-1, GLYCEROL Authors: Lam, S.Y, Sze, K.H, Wong, K.B. Deposit date: 2008-11-29 Release date: 2009-12-29 Last modified: 2012-02-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity. Plos Biol., 9, 2011
2W4D	Acylphosphatase variant G91A from Pyrococcus horikoshii Descriptor: ACYLPHOSPHATASE, PHOSPHATE ION, POTASSIUM ION Authors: Lam, S.Y, Wong, K.B. Deposit date: 2008-11-25 Release date: 2009-12-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity. Plos Biol., 9, 2011
2W4C	Human common-type acylphosphatase variant, A99 Descriptor: ACYLPHOSPHATASE-1 Authors: Lam, S.Y, Wong, K.B. Deposit date: 2008-11-25 Release date: 2009-12-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.52 Å) Cite: A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity. Plos Biol., 9, 2011
6DKK	Structure of BoNT Descriptor: Botulinum neurotoxin type A, PHOSPHATE ION Authors: Lam, K, Jin, R. Deposit date: 2018-05-29 Release date: 2018-12-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun, 9, 2018
1UQG	SELF-COMPLEMENTARY DNA 5'-D(CGCGCG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1UQA	SELF-COMPLEMENTARY DNA 5'-D(CATATG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*AP*TP*AP*TP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1UQC	SELF-COMPLEMENTARY DNA 5'-D(CACGTG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*AP*CP*GP*TP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1UQF	SELF-COMPLEMENTARY DNA 5'-D(CGGCCG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*GP*GP*CP*CP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1UQD	SELF-COMPLEMENTARY DNA 5'-D(CGATCG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1UQB	SELF-COMPLEMENTARY DNA 5'-D(CAGCTG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*AP*GP*CP*TP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1UQE	SELF-COMPLEMENTARY DNA 5'-D(CGTACG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-26 Release date: 1997-01-27 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
1BUF	SELF-COMPLEMENTARY DNA 5'-D(CAATTG)2, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: DNA (5'-D(*CP*AP*AP*TP*TP*G)-3') Authors: Lam, S.L, Au-Yeung, S.C.F. Deposit date: 1996-06-24 Release date: 1997-01-27 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Sequence-specific local structural variations in solution structures of d(CGXX'CG)2 and d(CAXX'TG)2 self-complementary deoxyribonucleic acids. J.Mol.Biol., 266, 1997
3K2A	Crystal structure of the homeobox domain of human homeobox protein Meis2 Descriptor: ACETATE ION, CHLORIDE ION, Homeobox protein Meis2 Authors: Lam, R, Soloveychik, M, Battaile, K.P, Romanov, V, Lam, K, Beletskaya, I, Gordon, E, Pai, E.F, Chirgadze, N.Y. Deposit date: 2009-09-29 Release date: 2010-10-13 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the homeobox domain of human homeobox protein Meis2 To be Published
3KOR	Crystal structure of a putative Trp repressor from Staphylococcus aureus Descriptor: Possible Trp repressor Authors: Lam, R, Vodsedalek, J, Lam, K, Romanov, V, Battaile, K.P, Beletskaya, I, Pai, E.F, Chirgadze, N.Y. Deposit date: 2009-11-13 Release date: 2010-11-17 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of a putative Trp repressor from Staphylococcus aureus To be Published
3L5A	Crystal structure of a probable NADH-dependent flavin oxidoreductase from Staphylococcus aureus Descriptor: NADH/flavin oxidoreductase/NADH oxidase, TRIETHYLENE GLYCOL Authors: Lam, R, Gordon, R.D, Vodsedalek, J, Battaile, K.P, Grebemeskel, S, Lam, K, Romanov, V, Chan, T, Mihajlovic, V, Thompson, C.M, Guthrie, J, Pai, E.F, Chirgadze, N.Y. Deposit date: 2009-12-21 Release date: 2010-12-22 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of a probable NADH-dependent flavin oxidoreductase from Staphylococcus aureus To be Published
3KWL	Crystal structure of a hypothetical protein from Helicobacter pylori Descriptor: uncharacterized protein Authors: Lam, R, Thompson, C.M, Vodsedalek, J, Lam, K, Romanov, V, Battaile, K.P, Beletskaya, I, Gordon, E, Pai, E.F, Chirgadze, N.Y. Deposit date: 2009-12-01 Release date: 2010-12-01 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Crystal structure of a hypothetical protein from Helicobacter pylori To be Published
7B5D	Structure of calcium-free mTMEM16A(ac)-I551A chloride channel at 3.3 A resolution Descriptor: Anoctamin-1 Authors: Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. Deposit date: 2020-12-03 Release date: 2021-02-10 Last modified: 2021-02-17 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021

 

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