Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5F59
DownloadVisualize
BU of 5f59 by Molmil
The crystal structure of MLL3 SET domain
Descriptor: Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Li, Y, Lei, M, Chen, Y.
Deposit date:2015-12-04
Release date:2016-02-24
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
DownloadVisualize
BU of 5f6k by Molmil
Crystal structure of the MLL3-Ash2L-RbBP5 complex
Descriptor: Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Li, Y, Lei, M, Chen, Y.
Deposit date:2015-12-06
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
6KIW
DownloadVisualize
BU of 6kiw by Molmil
Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom)
Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6MLC
DownloadVisualize
BU of 6mlc by Molmil
PHD6 domain of MLL3 in complex with histone H4
Descriptor: GLYCEROL, Histone H4, Histone-lysine N-methyltransferase 2C, ...
Authors:Dong, A, Liu, Y, Qin, S, Lei, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-09-27
Release date:2018-10-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.
Nat Commun, 10, 2019
2YSM
DownloadVisualize
BU of 2ysm by Molmil
Solution structure of the second and third PHD domain from Histone-lysine N-methyltransferase 2C (KMT2C/MLL3)
Descriptor: Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, ZINC ION
Authors:Qin, X.R, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2007-10-09
Last modified:2018-03-21
Method:SOLUTION NMR
Cite:Solution structure of the first and second PHD domain from Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
To be Published
7W6L
DownloadVisualize
BU of 7w6l by Molmil
The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide
Descriptor: Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ...
Authors:Zhao, L, Li, Y, Chen, Y.
Deposit date:2021-12-01
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
3UVL
DownloadVisualize
BU of 3uvl by Molmil
Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL3
Descriptor: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5
Authors:Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
Deposit date:2011-11-30
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
4ERY
DownloadVisualize
BU of 4ery by Molmil
X-ray structure of WDR5-MLL3 Win motif peptide binary complex
Descriptor: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5
Authors:Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
Deposit date:2012-04-21
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon