PDB: 18 resultsInfo pagesStatus searchChemie searchBIRD

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4M9E	Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA Descriptor: ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... Authors: Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. Deposit date: 2013-08-14 Release date: 2014-02-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.851 Å) Cite: Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res., 42, 2014
2WBS	Crystal structure of the zinc finger domain of Klf4 bound to its target DNA Descriptor: 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', GLYCEROL, ... Authors: Zocher, G, Schuetz, A, Carstanjen, D, Heinemann, U. Deposit date: 2009-03-03 Release date: 2010-04-07 Last modified: 2011-10-05 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation. Cell.Mol.Life Sci., 68, 2011
2WBU	CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA Descriptor: 5'-D(*DGP*DAP*DGP*DGP*DCP*DGP*DTP* DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DAP*DCP*DGP*DCP* DCP*DTP*DC)-3', KRUEPPEL-LIKE FACTOR 4, ... Authors: Schuetz, A, Zocher, G, Carstanjen, D, Heinemann, U. Deposit date: 2009-03-05 Release date: 2010-04-07 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation. Cell.Mol.Life Sci., 68, 2011
6VTX	Crystal structure of human KLF4 zinc finger DNA binding domain in complex with NANOG DNA Descriptor: DNA (5'-D(*AP*GP*GP*GP*GP*GP*TP*GP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*CP*AP*CP*CP*CP*CP*CP*T)-3'), Krueppel-like factor 4, ... Authors: Sharma, R, Sharma, S, Choi, K.J, Ferreon, A.C.M, Ferreon, J.C, Sankaran, B, MacKenzie, K.R, Kim, C. Deposit date: 2020-02-13 Release date: 2021-09-01 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization. Nat Commun, 12, 2021
5KE7	mouse Klf4 ZnF1-3 and TpG/MpA sequence DNA complex structure Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*AP*CP*CP*TP*C)-3'), ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2016-06-09 Release date: 2016-09-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KE6	mouse Klf4 ZnF1-3 and TpG/CpA sequence DNA complex structure Descriptor: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2016-06-09 Release date: 2016-09-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KEB	mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form II Descriptor: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2016-06-09 Release date: 2016-09-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.453 Å) Cite: Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KE8	mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure Descriptor: DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2016-06-09 Release date: 2016-09-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KE9	mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure Descriptor: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2016-06-09 Release date: 2016-09-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.336 Å) Cite: Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
5KEA	mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form I Descriptor: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ... Authors: Hashimoto, H, Cheng, X. Deposit date: 2016-06-09 Release date: 2016-09-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.458 Å) Cite: Distinctive Klf4 mutants determine preference for DNA methylation status. Nucleic Acids Res., 44, 2016
6UZK	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi6 Descriptor: 2-hydroxy-6-methoxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-11-15 Release date: 2020-11-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.924 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells. Faseb Bioadv, 3, 2021
6OQ4	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi1 Descriptor: 2-{(Z)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-[(1S)-1-phenylethyl]benzamide, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-04-25 Release date: 2020-06-24 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.754 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells Faseb Bioadv, 2021
6OQ3	Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi2 Descriptor: 2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ... Authors: Gingras, A.R. Deposit date: 2019-04-25 Release date: 2020-06-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells Faseb Bioadv, 2021
3L1P	POU protein:DNA complex Descriptor: DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ... Authors: Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M. Deposit date: 2009-12-14 Release date: 2010-12-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A unique Oct4 interface is crucial for reprogramming to pluripotency Nat.Cell Biol., 15, 2013
3X1V	Crystal structure of nucleosome core particle in the presence of histone variant involved in reprogramming Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... Authors: Sivaraman, P, Kumarevel, T.S. Deposit date: 2014-11-28 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.921 Å) Cite: Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming Biochem.Biophys.Res.Commun., 464, 2015
3X1U	Crystal structure of nucleosome core particle in the presence of histone variants involved in reprogramming Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A, ... Authors: Sivaraman, P, Kumarevel, T.S. Deposit date: 2014-11-28 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming. Biochem.Biophys.Res.Commun., 464, 2015
3X1T	Crystal structure of nucleosome core particle consisting of mouse testis specific histone variants H2aa and H2ba Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A, ... Authors: Sivaraman, P, Kumarevel, T.S. Deposit date: 2014-11-27 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.808 Å) Cite: Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming Biochem.Biophys.Res.Commun., 464, 2015
3X1S	Crystal structure of the nucleosome core particle Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... Authors: Sivaraman, P, Kumarevel, T.S. Deposit date: 2014-11-27 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.805 Å) Cite: Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming Biochem.Biophys.Res.Commun., 464, 2015