Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6SJA
DownloadVisualize
BU of 6sja by Molmil
Structure of HPV16 E6 oncoprotein in complex with IRF3 LxxLL motif
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3, Protein E6, ZINC ION, ...
Authors:Suarez, I.P, Cousido-Siah, A, Bonhoure, A, Mitschler, A, Podjarny, A, Trave, G.
Deposit date:2019-08-13
Release date:2019-09-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Deciphering de molecular and structural interaction between IRF3 and HPV16 E6
To be published
6SIV
DownloadVisualize
BU of 6siv by Molmil
Structure of HPV16 E6 oncoprotein in complex with mutant IRF3 LxxLL motif
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3, Protein E6, ZINC ION, ...
Authors:Suarez, I.P, Cousido-Siah, A, Bonhoure, A, Mitschler, A, Podjarny, A, Trave, G.
Deposit date:2019-08-12
Release date:2019-08-21
Last modified:2022-03-30
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Deciphering the molecular and structural interaction between IRF3 and HPV16 E6
To be published
8BTJ
DownloadVisualize
BU of 8btj by Molmil
Murine cytomegalovirus protein M35
Descriptor: (R,R)-2,3-BUTANEDIOL, MALONATE ION, Protein M35
Authors:Schmelz, S, Van den Heuvel, J, Blankenfeldt, W.
Deposit date:2022-11-29
Release date:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Cytomegalovirus M35 Protein Directly Binds to the Interferon-beta Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.
J.Virol., 97, 2023
1ZOQ
DownloadVisualize
BU of 1zoq by Molmil
IRF3-CBP complex
Descriptor: CREB-binding protein, Interferon regulatory factor 3
Authors:Qin, B, Lin, K.
Deposit date:2005-05-13
Release date:2006-03-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of IRF-3 in complex with CBP.
Structure, 13, 2005
1QWT
DownloadVisualize
BU of 1qwt by Molmil
Auto-inhibitory interferon regulation factor-3 (IRF3) transactivation domain
Descriptor: Interferon regulatory factor 3, PHOSPHATE ION
Authors:Qin, B.Y.
Deposit date:2003-09-03
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus induced phospho-activation
Nat.Struct.Biol., 10, 2003
2O61
DownloadVisualize
BU of 2o61 by Molmil
Crystal Structure of NFkB, IRF7, IRF3 bound to the interferon-b enhancer
Descriptor: 34-MER, 36-MER, Nuclear factor NF-kappa-B p105 subunit, ...
Authors:Panne, D.
Deposit date:2006-12-06
Release date:2007-07-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An Atomic Model of the Interferon-beta Enhanceosome.
Cell(Cambridge,Mass.), 129, 2007
1T2K
DownloadVisualize
BU of 1t2k by Molmil
Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA
Descriptor: 31-MER, Cyclic-AMP-dependent transcription factor ATF-2, Interferon regulatory factor 3, ...
Authors:Panne, D, Maniatis, T, Harrison, S.C.
Deposit date:2004-04-21
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-beta enhancer.
Embo J., 23, 2004
3A77
DownloadVisualize
BU of 3a77 by Molmil
The crystal structure of phosphorylated IRF-3
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, Interferon regulatory factor 3
Authors:Takahasi, K, Horiuchi, M, Noda, N.N, Inagaki, F.
Deposit date:2009-09-17
Release date:2010-08-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change.
Genes Cells, 15, 2010
2PI0
DownloadVisualize
BU of 2pi0 by Molmil
Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer
Descriptor: Interferon regulatory factor 3, PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2
Authors:Escalante, C.R, Nistal-Villan, E, Leyi, S, Garcia-Sastre, A, Aggarwal, A.K.
Deposit date:2007-04-12
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer.
Mol.Cell, 26, 2007
2O6G
DownloadVisualize
BU of 2o6g by Molmil
Crystal structure of IRF-3 bound to the interferon-b enhancer
Descriptor: Interferon regulatory factor 3, interferon-b enhancer
Authors:Panne, D.
Deposit date:2006-12-07
Release date:2007-07-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:An Atomic Model of the Interferon-beta Enhanceosome.
Cell(Cambridge,Mass.), 129, 2007
5JEJ
DownloadVisualize
BU of 5jej by Molmil
Phosphorylated STING in complex with IRF-3 CTD
Descriptor: Interferon regulatory factor 3, Stimulator of interferon genes protein
Authors:Li, P, Shu, C.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
1J2F
DownloadVisualize
BU of 1j2f by Molmil
X-ray crystal structure of IRF-3 and its functional implications
Descriptor: Interferon regulatory factor 3
Authors:Takahasi, K, Noda, N, Horiuchi, M, Mori, M, Okabe, Y, Fukuhara, Y, Terasawa, H, Fujita, T, Inagaki, F.
Deposit date:2003-01-04
Release date:2003-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of IRF-3 and its functional implications.
Nat.Struct.Biol., 10, 2003
5JEK
DownloadVisualize
BU of 5jek by Molmil
Phosphorylated MAVS in complex with IRF-3
Descriptor: Interferon regulatory factor 3, MAVS peptide
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JER
DownloadVisualize
BU of 5jer by Molmil
Structure of Rotavirus NSP1 bound to IRF-3
Descriptor: Interferon regulatory factor 3, Rotavirus NSP1 peptide
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JEL
DownloadVisualize
BU of 5jel by Molmil
Phosphorylated TRIF in complex with IRF-3
Descriptor: Interferon regulatory factor 3, Phosphorylated TRIF peptide
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JEO
DownloadVisualize
BU of 5jeo by Molmil
Phosphorylated Rotavirus NSP1 in complex with IRF-3
Descriptor: Interferon regulatory factor 3, PHOSPHATE ION, Rotavirus NSP1 peptide
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (1.719 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
7JFM
DownloadVisualize
BU of 7jfm by Molmil
Crystal structure of mouse phosphorylated IRF-3 bound to CBP
Descriptor: CREB-binding protein, Interferon regulatory factor 3
Authors:Li, P, Jing, T, Zhao, B.
Deposit date:2020-07-17
Release date:2020-09-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Structural Basis of IRF-3 Activation upon Phosphorylation.
J Immunol., 205, 2020
7JFL
DownloadVisualize
BU of 7jfl by Molmil
Crystal structure of human phosphorylated IRF-3 bound to CBP
Descriptor: CREB-binding protein, Interferon regulatory factor 3
Authors:Li, P, Jing, T, Zhao, B.
Deposit date:2020-07-17
Release date:2020-09-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Structural Basis of IRF-3 Activation upon Phosphorylation.
J Immunol., 205, 2020
5JEM
DownloadVisualize
BU of 5jem by Molmil
Complex of IRF-3 with CBP
Descriptor: CREB-binding protein, Interferon regulatory factor 3
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
4JC5
DownloadVisualize
BU of 4jc5 by Molmil
Immune activator bound to receptor
Descriptor: (9-oxoacridin-10(9H)-yl)acetic acid, Transmembrane protein 173
Authors:Deimling, T, Hopfner, K.P.
Deposit date:2013-02-21
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Species-specific detection of the antiviral small-molecule compound CMA by STING.
Embo J., 32, 2013
3QU6
DownloadVisualize
BU of 3qu6 by Molmil
Crystal structure of IRF-3 DBD free form
Descriptor: CHLORIDE ION, IRF3 protein, SODIUM ION, ...
Authors:De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K.
Deposit date:2011-02-23
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Nucleic Acids Res., 39, 2011
4EF4
DownloadVisualize
BU of 4ef4 by Molmil
Crystal structure of STING CTD complex with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173
Authors:Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J.
Deposit date:2012-03-29
Release date:2012-05-16
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.147 Å)
Cite:Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4EF5
DownloadVisualize
BU of 4ef5 by Molmil
Crystal structure of STING CTD
Descriptor: Transmembrane protein 173
Authors:Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J.
Deposit date:2012-03-29
Release date:2012-05-16
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4H9K
DownloadVisualize
BU of 4h9k by Molmil
Crystal structure of cleavage site mutant of Npro of classical swine fever virus.
Descriptor: Hog cholera virus, SULFATE ION, ZINC ION
Authors:Gottipati, K, Ruggli, N, Gerber, M, Tratschin, J.-D, Benning, M, Bellamy, H, Choi, K.H.
Deposit date:2012-09-24
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.
Plos Pathog., 9, 2013
4H9J
DownloadVisualize
BU of 4h9j by Molmil
Crystal structure of N-terminal protease (Npro) of classical swine fever virus.
Descriptor: Hog cholera virus
Authors:Gottipati, K, Ruggli, N, Gerber, M, Tratschin, J.-D, Benning, M, Bellamy, H, Choi, K.H.
Deposit date:2012-09-24
Release date:2013-10-30
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction.
Plos Pathog., 9, 2013

217157

PDB entries from 2024-03-13

PDB statisticsPDBj update infoContact PDBjnumon