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3QJ6
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BU of 3qj6 by Molmil
The crystal structure of PWWP domain of human Hepatoma-derived growth factor 2 in complex with H3K79me3 peptide
Descriptor: H3K79me3, Hepatoma-derived growth factor-related protein 2, SULFATE ION, ...
Authors:Zeng, H, Amaya, M.F, Tempel, W, Walker, J.R, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2011-01-28
Release date:2011-02-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
3JZH
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BU of 3jzh by Molmil
EED-H3K79me3
Descriptor: HISTONE PEPTIDE, Polycomb protein EED
Authors:Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
8HKR
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BU of 8hkr by Molmil
Crystal Structure of Histone H3 Lysine 79 (H3K79) Methyltransferase Rv2067c from Mycobacterium tuberculosis
Descriptor: PHOSPHATE ION, Protein lysine methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Dadireddy, V, Singh, P.R, Kalladi, S.M, Valakunja, N, Ramakumar, S.
Deposit date:2022-11-28
Release date:2023-10-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival.
Nat Commun, 14, 2023
2MV7
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BU of 2mv7 by Molmil
Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9)
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-9
Authors:Kuntimaddi, A, Bushweller, J.H.
Deposit date:2014-09-24
Release date:2015-04-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential.
Cell Rep, 11, 2015

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