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2KMK
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BU of 2kmk by Molmil
Gfi-1 Zinc Fingers 3-5 complexed with DNA
Descriptor: DNA (5'-D(*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP*TP*GP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*AP*GP*TP*GP*AP*TP*TP*TP*AP*TP*G)-3'), ZINC ION, ...
Authors:Lee, S, Wu, Z.
Deposit date:2009-07-30
Release date:2010-03-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of Gfi-1 zinc domain bound to consensus DNA.
J.Mol.Biol., 397, 2010
7XW8
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BU of 7xw8 by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct
Descriptor: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ...
Authors:Oki, H.
Deposit date:2022-05-26
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur.J.Med.Chem., 239, 2022

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