2KMK
| Gfi-1 Zinc Fingers 3-5 complexed with DNA | Descriptor: | DNA (5'-D(*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP*TP*GP*CP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*AP*GP*TP*GP*AP*TP*TP*TP*AP*TP*G)-3'), ZINC ION, ... | Authors: | Lee, S, Wu, Z. | Deposit date: | 2009-07-30 | Release date: | 2010-03-02 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of Gfi-1 zinc domain bound to consensus DNA. J.Mol.Biol., 397, 2010
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7XW8
| Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct | Descriptor: | GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ... | Authors: | Oki, H. | Deposit date: | 2022-05-26 | Release date: | 2022-10-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects. Eur.J.Med.Chem., 239, 2022
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