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8UNH	Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sliding clamp, ... Authors: Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. Deposit date: 2023-10-19 Release date: 2023-12-13 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
8UNF	Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp and DNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sliding clamp, ... Authors: Huang, Y, Marcus, K, Subramanian, S, Gee, L.C, Gorday, K, Ghaffari-Kashani, S, Luo, X, Zhang, L, O'Donnell, M, Subramanian, S, Kuriyan, J. Deposit date: 2023-10-18 Release date: 2023-12-13 Last modified: 2024-04-03 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
8UK9	Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, DNA primer, ... Authors: Marcus, K, Ghaffari-Kashani, S, Gee, C.L. Deposit date: 2023-10-12 Release date: 2023-12-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
8UH7	Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Primer DNA strand, ... Authors: Gee, C.L, Marcus, K, Kelch, B.A, Makino, D.L. Deposit date: 2023-10-07 Release date: 2023-12-13 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.628 Å) Cite: Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM. Nat.Struct.Mol.Biol., 31, 2024
8VAT	Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAN	Structure of the E. coli clamp loader bound to the beta clamp in an Initial-Binding conformation Descriptor: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... Authors: Landeck, J.T, Pajak, J, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (7.7 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAM	Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAS	Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
8VAP	Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (3 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 2024
1B77	BUILDING A REPLISOME STRUCTURE FROM INTERACTING PIECES: A SLIDING CLAMP COMPLEXED WITH AN INTERACTION PEPTIDE FROM DNA POLYMERASE Descriptor: PROTEIN (SLIDING CLAMP) Authors: Shamoo, Y, Steitz, T.A. Deposit date: 1999-01-27 Release date: 1999-02-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Cell(Cambridge,Mass.), 99, 1999
7EVP	Cryo-EM structure of the Gp168-beta-clamp complex Descriptor: Beta sliding clamp, Sliding clamp inhibitor Authors: Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. Deposit date: 2021-05-21 Release date: 2022-02-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Res., 49, 2021
8I6G	Crystal structure of the African swine fever virus DNA sliding clamp (native form) Descriptor: ASFV DNA sliding clamp Authors: Wu, J, Gong, P. Deposit date: 2023-01-28 Release date: 2023-06-07 Last modified: 2023-07-12 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Crystal structure of African swine fever virus pE301R reveals a ring-shaped trimeric DNA sliding clamp. J.Biol.Chem., 299, 2023
8I6H	Crystal structure of the African swine fever virus DNA sliding clamp (selenomethionine form) Descriptor: ASFV DNA sliding clamp Authors: Wu, J, Gong, P. Deposit date: 2023-01-28 Release date: 2023-06-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.292 Å) Cite: Crystal structure of African swine fever virus pE301R reveals a ring-shaped trimeric DNA sliding clamp. J.Biol.Chem., 299, 2023
8PAT	Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 3. Descriptor: ACE-GLN-ALC-GLX-LEU-PHE, Beta sliding clamp Authors: Compain, G, Monsarrat, C, Blagojevic, J, Brillet, K, Dumas, P, Hammann, P, Kuhn, L, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Burnouf, D, Guichard, G. Deposit date: 2023-06-08 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp. Jacs Au, 4, 2024
6E8E	Crystal structure of the Escherichia coli sliding clamp-MutL complex. Descriptor: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL, SULFATE ION Authors: Guarne, A, Almawi, A.W. Deposit date: 2018-07-28 Release date: 2019-05-01 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific. Nucleic Acids Res., 47, 2019
8PAY	Structure of the E.coli DNA polymerase sliding clamp with a covalently bound peptide 2. Descriptor: ACE-GLN-ALC-GLC-LEU-PHE, Beta sliding clamp, GLYCEROL, ... Authors: Compain, G, Monsarrat, C, Blagojevic, J, Brillet, K, Dumas, P, Hammann, P, Kuhn, L, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Burnouf, D, wagner, J, Guichard, G. Deposit date: 2023-06-08 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.21 Å) Cite: Peptide-Based Covalent Inhibitors Bearing Mild Electrophiles to Target a Conserved His Residue of the Bacterial Sliding Clamp. Jacs Au, 4, 2024
6E8D	Crystal structure of the Bacillus subtilis sliding clamp-MutL complex. Descriptor: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL Authors: Guarne, A, Almawi, A.W. Deposit date: 2018-07-28 Release date: 2019-05-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific. Nucleic Acids Res., 47, 2019
6FVL	DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide Descriptor: Beta sliding clamp, GLYCEROL, P7 peptide, ... Authors: Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. Deposit date: 2018-03-04 Release date: 2019-04-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.975 Å) Cite: Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6FVM	Mutant DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide Descriptor: Beta sliding clamp, CALCIUM ION, GLYCEROL, ... Authors: Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. Deposit date: 2018-03-04 Release date: 2019-04-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.631 Å) Cite: Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6FVO	Mutant DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide Descriptor: Beta sliding clamp, CALCIUM ION, P7 peptide Authors: Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. Deposit date: 2018-03-04 Release date: 2019-04-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.689 Å) Cite: Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6FVN	DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide Descriptor: Beta sliding clamp, P7 peptide Authors: Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. Deposit date: 2018-03-04 Release date: 2019-04-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.142 Å) Cite: Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
3FDS	Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase IV, ... Authors: Ling, H. Deposit date: 2008-11-26 Release date: 2009-01-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA Mol.Microbiol., 71, 2009

 

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