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7LO0
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BU of 7lo0 by Molmil
Structure of human ASF1a in complex with a TLK2 peptide
Descriptor: Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2
Authors:Simon, B, Calderwood, D, Turk, B.E, Boggon, T.J.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
7LNY
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BU of 7lny by Molmil
Apo structure of the Histone chaperone ASF1A residues 1-155
Descriptor: Histone chaperone ASF1A
Authors:Simon, B, Boggon, T.J, Calderwood, D, Turk, B.E.
Deposit date:2021-02-08
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
2I32
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BU of 2i32 by Molmil
Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly
Descriptor: Anti-Silencing Factor 1 paralog a, Histone Regulatory homolog A
Authors:Marmorstein, R, Tang, Y.
Deposit date:2006-08-17
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.
Nat.Struct.Mol.Biol., 13, 2006
7V6Q
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BU of 7v6q by Molmil
Crystal structure of sNASP-ASF1A-H3.1-H4 complex
Descriptor: GLYCEROL, Histone H3.1, Histone H4, ...
Authors:Liu, C.P, Xu, R.M.
Deposit date:2021-08-20
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
2IIJ
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BU of 2iij by Molmil
Structure of human Asf1a in complex with histone H3
Descriptor: ASF1A protein, Histone H3
Authors:Agez, M, Guerois, R, van Heijenoort, C, Mann, C, Ochsenbein, F.
Deposit date:2006-09-28
Release date:2007-02-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure of the histone chaperone asf1 bound to the histone h3 C-terminal helix and functional insights.
Structure, 15, 2007
5XBK
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BU of 5xbk by Molmil
Crystal structure of human Importin4
Descriptor: Importin-4, histone H3
Authors:Song, J.J, Yoon, J.
Deposit date:2017-03-20
Release date:2018-02-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.223 Å)
Cite:Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding
J. Mol. Biol., 430, 2018
5XAH
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BU of 5xah by Molmil
Crystal structure of human Importin4
Descriptor: Importin-4
Authors:Song, J.J, Yoon, J.
Deposit date:2017-03-13
Release date:2018-02-14
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding
J. Mol. Biol., 430, 2018
3AAD
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BU of 3aad by Molmil
Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction
Descriptor: Histone chaperone ASF1A, SULFATE ION, Transcription initiation factor TFIID subunit 1
Authors:Akai, Y, Adachi, N, Hayashi, Y, Eitoku, M, Sano, N, Natsume, R, Kudo, N, Tanokura, M, Senda, T, Horikoshi, M.
Deposit date:2009-11-16
Release date:2010-04-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction
Proc.Natl.Acad.Sci.USA, 107, 2010
5C3I
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BU of 5c3i by Molmil
Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Descriptor: DNA replication licensing factor MCM2,MCM2, Histone H3.1, Histone H4, ...
Authors:Wang, H, Wang, M, Yang, N, Xu, R.M.
Deposit date:2015-06-17
Release date:2015-07-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Protein Cell, 6, 2015
6ZUF
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BU of 6zuf by Molmil
Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone
Descriptor: C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Mbianda, J, Perrin, E.M, Guerois, R, Legrand, P, Traore, S, Douat, C, Guichard, G, Ochsenbein, F.
Deposit date:2020-07-22
Release date:2021-06-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
Sci Adv, 7, 2021
6F0G
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BU of 6f0g by Molmil
Crystal structure ASF1-ip3
Descriptor: Histone chaperone ASF1A, SULFATE ION, ip3
Authors:Gaubert, A, Guichard, B, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0F
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Crystal structure ASF1-ip2_s
Descriptor: Histone chaperone ASF1A, ip2_s
Authors:Gaubert, A, Guichard, B, Murciano, B, Le Du, M.H, Ochsenbein, F, Guerois, R, Andreani, J.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
6F0H
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BU of 6f0h by Molmil
Crystal structure ASF1-ip4
Descriptor: CITRIC ACID, GLYCEROL, Histone chaperone ASF1A, ...
Authors:Bakail, M, Richet, N, Le Du, M.H, Andreani, J, Guerois, R, Ochsenbein, F.
Deposit date:2017-11-20
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.
Cell Chem Biol, 26, 2019
8BV1
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BU of 8bv1 by Molmil
Peptide inhibitor P4 in complex with ASF1 histone chaperone
Descriptor: GLYCEROL, Histone chaperone ASF1A, P4 peptide inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2022-12-01
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ3
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BU of 8cj3 by Molmil
Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone
Descriptor: Histone chaperone ASF1A, c3u_7 chimera inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ1
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BU of 8cj1 by Molmil
Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone
Descriptor: Histone chaperone ASF1A, c3u_3 chimera inhibitor of histone chaperone ASF1
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.564 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
8CJ2
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BU of 8cj2 by Molmil
Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone
Descriptor: GLYCEROL, Histone chaperone ASF1A, SULFATE ION, ...
Authors:Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G.
Deposit date:2023-02-11
Release date:2023-07-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.127 Å)
Cite:Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Chem.Commun.(Camb.), 59, 2023
2IO5
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BU of 2io5 by Molmil
Crystal structure of the CIA- histone H3-H4 complex
Descriptor: ASF1A protein, Histone H3.1, Histone H4
Authors:Natsume, R, Akai, Y, Horikoshi, M, Senda, T.
Deposit date:2006-10-10
Release date:2007-02-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4.
Nature, 446, 2007
1TEY
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BU of 1tey by Molmil
NMR structure of human histone chaperone, ASF1A
Descriptor: ASF1 anti-silencing function 1 homolog A
Authors:Mousson, F, Lautrette, A, Thuret, J.Y, Agez, M, Amigues, B, Courbeyrette, R, Neumann, J.M, Guerois, R, Mann, C, Ochsenbein, F.
Deposit date:2004-05-26
Release date:2005-04-12
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural basis for the interaction of Asf1 with histone H3 and its functional implications.
Proc.Natl.Acad.Sci.Usa, 102, 2005
4ZBJ
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BU of 4zbj by Molmil
UBN1 peptide bound to H3.3/H4/Asf1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ...
Authors:Marmorstein, R, Ricketts, M.D, Tang, Y.
Deposit date:2015-04-14
Release date:2015-07-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex.
Nat Commun, 6, 2015

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