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3MUV
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BU of 3muv by Molmil
Crystal Structure of the G20A/C92U mutant c-di-GMP riboswith bound to c-di-AMP
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, G20A/C92U mutant c-di-GMP riboswitch, MAGNESIUM ION, ...
Authors:Strobel, S.A, Smith, K.D.
Deposit date:2010-05-03
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .
Biochemistry, 49, 2010
7QZP
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BU of 7qzp by Molmil
Identification and characterization of an RRM-containing, ELAV-like, RNA binding protein in Acinetobacter Baumannii
Descriptor: Hypothetical RNA binding protein from Acinetobacter baumannii
Authors:Ciani, C, Perez-Rafols, A, Bonomo, I, Micaelli, M, Esposito, A, Zucal, C, Belli, R, D'Agostino, V.G, Bianconi, I, Calderone, V, Cerofolini, L, Fragai, M, Provenzani, A.
Deposit date:2022-01-31
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii .
Biomolecules, 12, 2022
7QR3
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BU of 7qr3 by Molmil
Chimpanzee CPEB3 HDV-like ribozyme
Descriptor: GLYCEROL, POTASSIUM ION, U1 small nuclear ribonucleoprotein A, ...
Authors:Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022
7QR4
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BU of 7qr4 by Molmil
human CPEB3 HDV-like ribozyme
Descriptor: RNA CPEB3 ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022
3NMR
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BU of 3nmr by Molmil
Crystal Structure of CUGBP1 RRM1/2-RNA Complex
Descriptor: CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3')
Authors:Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J.
Deposit date:2010-06-22
Release date:2010-10-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18, 2010
3NNC
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BU of 3nnc by Molmil
Crystal Structure of CUGBP1 RRM1/2-RNA Complex
Descriptor: CUGBP Elav-like family member 1, RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*UP*GP*UP*GP*UP*G)-3')
Authors:Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J.
Deposit date:2010-06-23
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2005 Å)
Cite:Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18, 2010
3NNA
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BU of 3nna by Molmil
Crystal Structure of CUGBP1 RRM1/2-RNA Complex
Descriptor: CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3')
Authors:Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J.
Deposit date:2010-06-23
Release date:2010-10-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18, 2010
3NS6
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BU of 3ns6 by Molmil
Crystal structure of hte RNA recognition motif of yeast eIF3b residues 76-170
Descriptor: Eukaryotic translation initiation factor 3 subunit B, SULFATE ION
Authors:Khoshnevis, S, Neumann, P, Ficner, R.
Deposit date:2010-07-01
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b.
Plos One, 5, 2010
3NNH
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BU of 3nnh by Molmil
Crystal Structure of the CUGBP1 RRM1 with GUUGUUUUGUUU RNA
Descriptor: CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3')
Authors:Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J.
Deposit date:2010-06-23
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7501 Å)
Cite:Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18, 2010
3NS5
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BU of 3ns5 by Molmil
Crystal structure of the RNA recognition motif of yeast eIF3b residues 76-161
Descriptor: Eukaryotic translation initiation factor 3 subunit B
Authors:Khoshnevis, S, Neumann, P, Ficner, R.
Deposit date:2010-07-01
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b.
Plos One, 5, 2010
7S3B
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BU of 7s3b by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2022-06-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3A
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BU of 7s3a by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3C
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BU of 7s3c by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Glasser, E, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7SN6
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BU of 7sn6 by Molmil
U2AF65 UHM BOUND TO SF3B155 ULM5
Descriptor: ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit
Authors:Loerch, S, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-10-27
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J.Biol.Chem., 298, 2022
3P49
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BU of 3p49 by Molmil
Crystal Structure of a Glycine Riboswitch from Fusobacterium nucleatum
Descriptor: GLYCINE, GLYCINE RIBOSWITCH, MAGNESIUM ION, ...
Authors:Butler, E.B, Wang, J, Xiong, Y, Strobel, S.
Deposit date:2010-10-06
Release date:2011-04-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structural basis of cooperative ligand binding by the glycine riboswitch.
Chem.Biol., 18, 2011
3R1H
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BU of 3r1h by Molmil
Crystal structure of the Class I ligase ribozyme-substrate preligation complex, C47U mutant, Ca2+ bound
Descriptor: 5'-R(*UP*CP*CP*AP*GP*UP*A)-3', CALCIUM ION, Class I ligase ribozyme, ...
Authors:Shechner, D.M, Bartel, D.P.
Deposit date:2011-03-10
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The structural basis of RNA-catalyzed RNA polymerization.
Nat.Struct.Mol.Biol., 18, 2011
5X3Z
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BU of 5x3z by Molmil
Solution structure of musashi1 RBD2 in complex with RNA
Descriptor: RNA (5'-R(*GP*UP*AP*GP*U)-3'), RNA-binding protein Musashi homolog 1
Authors:Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M.
Deposit date:2017-02-09
Release date:2017-12-13
Method:SOLUTION NMR
Cite:Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
5X3Y
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BU of 5x3y by Molmil
Refined solution structure of musashi1 RBD2
Descriptor: RNA-binding protein Musashi homolog 1
Authors:Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M.
Deposit date:2017-02-09
Release date:2017-12-13
Method:SOLUTION NMR
Cite:Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
5ZUH
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BU of 5zuh by Molmil
Solution structure of RRM domian of La protein from Trypanosoma brucei
Descriptor: RNA binding protein La-like protein
Authors:Shan, F.Z.
Deposit date:2018-05-07
Release date:2019-05-15
Last modified:2019-09-04
Method:SOLUTION NMR
Cite:A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis.
Febs J., 286, 2019
6C8U
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BU of 6c8u by Molmil
Solution structure of Musashi2 RRM1
Descriptor: RNA-binding protein Musashi homolog 2
Authors:Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L.
Deposit date:2018-01-25
Release date:2019-01-30
Last modified:2022-03-23
Method:SOLUTION NMR
Cite:Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 2019
6CMN
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BU of 6cmn by Molmil
Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7
Descriptor: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element
Authors:Belashov, I.A, Wedekind, J.E.
Deposit date:2018-03-05
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription.
Nucleic Acids Res., 46, 2018
6XH3
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BU of 6xh3 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.3
Descriptor: TAR BINDING PROTEIN TBP 6.3, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XH2
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BU of 6xh2 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6
Descriptor: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XLX
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BU of 6xlx by Molmil
Crystal structure of cancer-associated G301D mutant of U2AF65 bound to AdML splice site
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2020-06-29
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
7VSJ
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BU of 7vsj by Molmil
Crystal structure of MmIMP3-RRM12 in complex with 9-mer RNA
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (9-mer)
Authors:Li, X.J, Wu, B.X.
Deposit date:2021-10-26
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of MmIMP3-RRM12 in complex with 9-mer RNA
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