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2BN3
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BU of 2bn3 by Molmil
Insulin before a high dose x-ray burn
Descriptor: INSULIN
Authors:Nanao, M.H, Ravelli, R.B.
Deposit date:2005-03-18
Release date:2005-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Improving Radiation-Damage Substructures for Rip.
Acta Crystallogr.,Sect.D, 61, 2005
2BN1
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BU of 2bn1 by Molmil
Insulin after a high dose x-ray burn
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Nanao, M.H, Ravelli, R.B.
Deposit date:2005-03-18
Release date:2005-09-07
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Improving Radiation-Damage Substructures for Rip.
Acta Crystallogr.,Sect.D, 61, 2005
2C8Q
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BU of 2c8q by Molmil
insuline(1sec) and UV laser excited fluorescence
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D.
Deposit date:2005-12-06
Release date:2006-03-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops.
Acta Crystallogr.,Sect.D, 62, 2006
2C8R
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BU of 2c8r by Molmil
insuline(60sec) and UV laser excited fluorescence
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D.
Deposit date:2005-12-06
Release date:2006-03-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops.
Acta Crystallogr.,Sect.D, 62, 2006
2EFA
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BU of 2efa by Molmil
Neutron crystal structure of cubic insulin at pD6.6
Descriptor: Insulin
Authors:Ishikawa, T, Tanaka, I, Niimura, N.
Deposit date:2007-02-22
Release date:2008-01-22
Last modified:2023-10-25
Method:NEUTRON DIFFRACTION (2.7 Å)
Cite:A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6
Chem.Phys., 345, 2008
5T7R
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BU of 5t7r by Molmil
A6-A11 trans-dicarba human insulin
Descriptor: Insulin A chain, Insulin B chain
Authors:Menting, J.G, Lawrence, M.C, Robinson, A.J, Forbes, B.E.
Deposit date:2016-09-05
Release date:2017-12-06
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity.
Sci Rep, 7, 2017
5UDP
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BU of 5udp by Molmil
High resolution x-ray crystal structure of synthetic insulin lispro
Descriptor: CHLORIDE ION, Insulin Lispro A chain, Insulin Lispro B chain, ...
Authors:Mandal, K, Dhayalan, B, Kent, S.B.H.
Deposit date:2016-12-28
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.348 Å)
Cite:Scope and Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin.
Chemistry, 23, 2017
5USP
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BU of 5usp by Molmil
Insulin with proline analog Pip at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-13
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.174 Å)
Cite:Insulin with proline analog Pip at position B28 in the T2 state
To Be Published
5UU4
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BU of 5uu4 by Molmil
Insulin with proline analog ThioP at position B28 in the R6 state
Descriptor: CHLORIDE ION, Insulin A Chain, Insulin B Chain, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-16
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Insulin with proline analog ThioP at position B28 in the R6 state
To Be Published
5USS
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BU of 5uss by Molmil
Insulin with proline analog PiP at position B28 in the R6 state
Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-13
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.061 Å)
Cite:Insulin with proline analog PiP at position B28 in the R6 state
To Be Published
5UU2
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BU of 5uu2 by Molmil
Insulin with proline analog ThioP at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-15
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.223 Å)
Cite:Insulin with proline analog ThioP at position B28 in the T2 state
To Be Published
5USV
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BU of 5usv by Molmil
Insulin with proline analog AzeP at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-14
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Insulin with proline analog AzeP at position B28 in the T2 state
To Be Published
5UOZ
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BU of 5uoz by Molmil
Insulin with proline analog FyP at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-01
Release date:2018-02-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.17463875 Å)
Cite:Insulin with proline analog FyP at position B28 in the T2 state
To Be Published
5URU
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BU of 5uru by Molmil
Insulin with proline analog DhP at position B28 in the R6 state
Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-13
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Insulin with proline analog DhP at position B28 in the R6 state
To Be Published
5UQA
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BU of 5uqa by Molmil
Insulin with proline analog FzP at position B28 in the R6 state
Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-07
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.31000245 Å)
Cite:Insulin with proline analog FzP at position B28 in the R6 state
To Be Published
5UU3
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BU of 5uu3 by Molmil
Insulin with proline analog DfP at position B28 in the R6 state
Descriptor: CHLORIDE ION, Insulin, chain A, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-16
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Insulin with proline analog DfP at position B28 in the R6 state
To Be Published
5URT
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BU of 5urt by Molmil
Insulin with proline analog DhP at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-12
Release date:2018-02-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Insulin with proline analog DhP at position B28 in the T2 state
To Be Published
5VIZ
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BU of 5viz by Molmil
X-Ray structure of Insulin Glargine
Descriptor: Insulin, chain alpha, chain beta
Authors:Reyes-Grajeda, J.P, Romero, A.
Deposit date:2017-04-17
Release date:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-Ray structure of Insulin Glargine
To Be Published
5WDM
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BU of 5wdm by Molmil
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein
Descriptor: Single-chain insulin analog
Authors:Yee, V.C, Aldabbagh, K, Peng, Y.
Deposit date:2017-07-05
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.
J. Biol. Chem., 293, 2018
5WBT
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BU of 5wbt by Molmil
Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING
Descriptor: Insulin
Authors:Glidden, M.D, Yang, Y, Wickramasinghe, N.P, Weiss, M.A.
Deposit date:2017-06-29
Release date:2017-11-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.
J. Biol. Chem., 293, 2018
5AZZ
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BU of 5azz by Molmil
Crystal structure of seleno-insulin
Descriptor: Insulin A chain, Insulin B chain
Authors:Watanabe, S, Okumura, M, Arai, K, Takei, T, Asahina, Y, Hojo, H, Iwaoka, M, Inaba, K.
Deposit date:2015-10-23
Release date:2017-05-03
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue.
Angew. Chem. Int. Ed. Engl., 56, 2017
5BTS
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BU of 5bts by Molmil
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
Descriptor: Insulin A chain, Insulin B chain
Authors:Norrman, M, Hjorth, C.F.
Deposit date:2015-06-03
Release date:2016-03-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
J.Pharm.Sci., 105, 2016
5BOQ
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BU of 5boq by Molmil
Human insulin with intra-chain chemical crosslink between modified B24 and B29
Descriptor: Insulin, SULFATE ION
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2015-05-27
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
5BPO
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BU of 5bpo by Molmil
Human insulin with intra-chain chemical crosslink between modified B27 and B29
Descriptor: Insulin
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2015-05-28
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
5CO6
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BU of 5co6 by Molmil
Crystal structure of human zinc insulin at pH 6.5
Descriptor: CHLORIDE ION, Insulin, MAGNESIUM ION, ...
Authors:Lima, L.M.T.R, PALMIERI, L.C.
Deposit date:2015-07-19
Release date:2015-08-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human zinc insulin at pH 6.5
To Be Published

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