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5M9T
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Human angiogenin ALS variant H114R
Descriptor: Angiogenin, BORATE ION, GLYCEROL
Authors:Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R.
Deposit date:2016-11-02
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Sci Rep, 7, 2017
5M9Q
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BU of 5m9q by Molmil
Human angiogenin PD variant R95Q
Descriptor: Angiogenin, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
Authors:Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R.
Deposit date:2016-11-02
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Sci Rep, 7, 2017
5M9G
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BU of 5m9g by Molmil
Human angiogenin PD variant K54R
Descriptor: Angiogenin, D(-)-TARTARIC ACID, DI(HYDROXYETHYL)ETHER
Authors:Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R.
Deposit date:2016-11-01
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Sci Rep, 7, 2017
5E5E
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BU of 5e5e by Molmil
X-ray structure of the adduct formed in the reaction between RNase A and a neutral organometallic derivative [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3)
Descriptor: DIMETHYL SULFOXIDE, PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Merlino, A.
Deposit date:2015-10-08
Release date:2015-12-09
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
5M9S
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BU of 5m9s by Molmil
Human angiogenin ALS variant V103I
Descriptor: Angiogenin, D(-)-TARTARIC ACID
Authors:Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R.
Deposit date:2016-11-02
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Sci Rep, 7, 2017
5M9V
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BU of 5m9v by Molmil
Human angiogenin PD/ALS variant R121C
Descriptor: Angiogenin, GLUTATHIONE, L(+)-TARTARIC ACID
Authors:Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R.
Deposit date:2016-11-02
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Sci Rep, 7, 2017
5E5F
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BU of 5e5f by Molmil
X-ray structure of the complex between RNase A and compound 4-PF6 ([(PPh3)Au(mi-pbi)Pt(Me)(DMSO)][PF6]), the heterobimetallic derivative obtained in the reaction between the organometallic compound [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3) and the gold(I) compound [Au(Ph3P)][PF6]
Descriptor: ACETATE ION, GOLD ION, Ribonuclease pancreatic, ...
Authors:Merlino, A.
Deposit date:2015-10-08
Release date:2015-12-09
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
5E13
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Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c
Descriptor: 3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine, Non-secretory ribonuclease
Authors:Chatzileontiadou, D.S.M, Stravodimos, G.A, Kantsadi, A.L, Leonidas, D.D.
Deposit date:2015-09-29
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.
Bioorg.Chem., 63, 2015
5NA9
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The X-ray structure of bovine pancreatic ribonuclease incubated in the presence of an excess of carboplatin (1:10 ratio)
Descriptor: CESIUM ION, CHLORIDE ION, Ribonuclease pancreatic, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-02-27
Release date:2017-08-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin.
J. Inorg. Biochem., 173, 2017
5EQO
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BU of 5eqo by Molmil
Human Angiogenin in complex with sulphate anions at an acidic solution
Descriptor: Angiogenin, SULFATE ION
Authors:Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2015-11-13
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5EPZ
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BU of 5epz by Molmil
Human Angiogenin in complex with sulphate anions at a basic solution
Descriptor: Angiogenin, GLYCEROL, SULFATE ION
Authors:Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2015-11-12
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5NJ7
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BU of 5nj7 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and arsenoplatin-1
Descriptor: Ribonuclease pancreatic, arsenoplatin-1
Authors:Ferraro, G, Merlino, A.
Deposit date:2017-03-28
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Arsenoplatin-1 Is a Dual Pharmacophore Anticancer Agent.
J.Am.Chem.Soc., 141, 2019
5EOP
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BU of 5eop by Molmil
Crystal structure of human Angiogenin at 1.35 Angstroms resolution
Descriptor: Angiogenin
Authors:Chatzileontiadou, D.S.M, Tsirkone, V.G, Dossi, K, Leonidas, D.D.
Deposit date:2015-11-10
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The ammonium sulfate inhibition of human angiogenin.
Febs Lett., 590, 2016
5ET4
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BU of 5et4 by Molmil
Structure of RNase A-K7H/R10H in complex with 3'-CMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-3'-MONOPHOSPHATE, Ribonuclease pancreatic
Authors:Blanco, J.A, Salazar, V.A, Moussaoui, M, Boix, E.
Deposit date:2015-11-17
Release date:2016-11-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates.
Biochim Biophys Acta Gen Subj, 1863, 2019
4K7M
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BU of 4k7m by Molmil
Crystal structure of RNase S variant (K7C/Q11C) with bound mercury ions
Descriptor: MERCURY (II) ION, Ribonuclease pancreatic, SULFATE ION
Authors:Genz, M, Straeter, N.
Deposit date:2013-04-17
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Apo- and Metalated Thiolate containing RNase S as Structural Basis for the Design of Artificial Metalloenzymes by Peptide- Protein Complementation
Z.Anorg.Allg.Chem., 639, 2013
11BA
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BU of 11ba by Molmil
BINDING OF A SUBSTRATE ANALOGUE TO A DOMAIN SWAPPING PROTEIN IN THE COMPLEX OF BOVINE SEMINAL RIBONUCLEASE WITH URIDYLYL-2',5'-ADENOSINE
Descriptor: PROTEIN (RIBONUCLEASE, SEMINAL), SULFATE ION, ...
Authors:Vitagliano, L, Adinolfi, S, Riccio, A, Sica, F, Zagari, A, Mazzarella, L.
Deposit date:1999-03-17
Release date:1999-03-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2',5')adenosine.
Protein Sci., 7, 1998
11BG
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BU of 11bg by Molmil
A POTENTIAL ALLOSTERIC SUBSITE GENERATED BY DOMAIN SWAPPING IN BOVINE SEMINAL RIBONUCLEASE
Descriptor: PROTEIN (BOVINE SEMINAL RIBONUCLEASE), SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE
Authors:Vitagliano, L, Adinolfi, S, Sica, F, Merlino, A, Zagari, A, Mazzarella, L.
Deposit date:1999-03-11
Release date:1999-11-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease.
J.Mol.Biol., 293, 1999
1A2W
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BU of 1a2w by Molmil
CRYSTAL STRUCTURE OF A 3D DOMAIN-SWAPPED DIMER OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: CHLORIDE ION, RIBONUCLEASE A, SULFATE ION
Authors:Liu, Y, Hart, P.J, Schlunegger, M.P, Eisenberg, D.S.
Deposit date:1998-01-12
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 95, 1998
1AFK
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BU of 1afk by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-DIPHOSPHOADENOSINE-3'-PHOSPHATE
Descriptor: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, RIBONUCLEASE A
Authors:Leonidas, D.D, Acharya, K.R.
Deposit date:1997-03-08
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
1A5Q
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BU of 1a5q by Molmil
P93A VARIANT OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:Pearson, M.A, Karplus, P.A, Dodge, R.W, Laity, J.H, Scheraga, H.A.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A.
Protein Sci., 7, 1998
1ANG
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BU of 1ang by Molmil
CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN REVEALS THE STRUCTURAL BASIS FOR ITS FUNCTIONAL DIVERGENCE FROM RIBONUCLEASE
Descriptor: ANGIOGENIN
Authors:Acharya, K.R, Allen, S, Shapiro, R, Riordan, J.F, Vallee, B.L.
Deposit date:1994-01-18
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease.
Proc.Natl.Acad.Sci.USA, 91, 1994
1AGI
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BU of 1agi by Molmil
CRYSTAL STRUCTURE OF BOVINE ANGIOGENIN AT 1.5 ANGSTROMS RESOLUTION
Descriptor: ANGIOGENIN
Authors:Acharya, K.R, Shapiro, R, Riordan, J.F, Vallee, B.L.
Deposit date:1995-01-06
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of bovine angiogenin at 1.5-A resolution.
Proc.Natl.Acad.Sci.USA, 92, 1995
4KXH
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BU of 4kxh by Molmil
The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ...
Authors:Pica, A, Merlino, A, Mazzarella, L, Sica, F.
Deposit date:2013-05-26
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.
Acta Crystallogr.,Sect.D, 69, 2013
1AFU
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BU of 1afu by Molmil
STRUCTURE OF RIBONUCLEASE A AT 2.0 ANGSTROMS FROM MONOCLINIC CRYSTALS
Descriptor: RIBONUCLEASE A
Authors:Leonidas, D.D, Acharya, K.R.
Deposit date:1997-03-14
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
4L55
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BU of 4l55 by Molmil
X-ray structure of the adduct between bovine pancreatic ribonuclease and AziRu
Descriptor: RUTHENIUM ION, Ribonuclease pancreatic
Authors:Vergara, A, Russo Krauss, I, Merlino, A.
Deposit date:2013-06-10
Release date:2014-01-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu.
Inorg.Chem., 52, 2013

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