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2B00
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycocholate
Descriptor: CALCIUM ION, GLYCOCHOLIC ACID, Phospholipase A2, ...
Authors:Pan, Y.H, Bahnson, B.J, Jain, M.K.
Deposit date:2005-09-12
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B01
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Pan, Y.H, Bahnson, B.J, Jain, M.K.
Deposit date:2005-09-12
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B03
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate
Descriptor: CALCIUM ION, Phospholipase A2, major isoenzyme, ...
Authors:Pan, Y.H, Bahnson, B.J, Jain, M.K.
Deposit date:2005-09-12
Release date:2006-11-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B04
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycochenodeoxycholate
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCOCHENODEOXYCHOLIC ACID, ...
Authors:Pan, Y.H, Bahnson, B.J, Jain, M.K.
Deposit date:2005-09-12
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
2B17
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Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: Crystal structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution:
Descriptor: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Jabeen, T, Sharma, S, Singh, T.P.
Deposit date:2005-09-15
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
2B96
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Third Calcium ion found in an inhibitor bound phospholipase A2
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-METHOXYBENZOIC ACID, CALCIUM ION, ...
Authors:Sekar, K, Velmurugan, D, Yamane, T, Tsai, M.D.
Deposit date:2005-10-11
Release date:2006-03-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Third Calcium ion found in an inhibitor bound phospholipase A2
Acta Crystallogr.,Sect.D, 62, 2006
2BAX
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Atomic Resolution Structure of the Double Mutant (K53,56M) of Bovine Pancreatic Phospholipase A2
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
Authors:Sekar, K, Yogavel, M, Velmurugan, D, Dauter, Z, Dauter, M, Tsai, M.D.
Deposit date:2005-10-15
Release date:2005-10-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2.
Acta Crystallogr.,Sect.F, 61, 2005
2BCH
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A possible of Second calcium ion in interfacial binding: Atomic and Medium resolution crystal structures of the quadruple mutant of phospholipase A2
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Sekar, K, Yogavel, M, Velmurugan, D, Poi, M.J, Dauter, Z, Tsai, M.D.
Deposit date:2005-10-19
Release date:2006-07-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A(2).
Acta Crystallogr.,Sect.D, 62, 2006
2BD1
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A possible role of the second calcium ion in interfacial binding: Atomic and medium resolution crystal structures of the quadruple mutant of phospholipase A2
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Phospholipase A2
Authors:Sekar, K, Velmurugan, D, Tsai, M.D.
Deposit date:2005-10-19
Release date:2006-07-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A(2).
Acta Crystallogr.,Sect.D, 62, 2006
2BP2
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THE STRUCTURE OF BOVINE PANCREATIC PROPHOSPHOLIPASE A2 AT 3.0 ANGSTROMS RESOLUTION
Descriptor: PHOSPHOLIPASE A2
Authors:Dijkstra, B.W, Vannes, G.J.H, Kalk, K.H, Brandenburg, N.P, Hol, W.G.J, Drenth, J.
Deposit date:1981-06-05
Release date:1981-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of Bovine Pancreatic Prophospholipase A2 at 3.0 Angstroms Resolution
Acta Crystallogr.,Sect.B, 38, 1982
2BPP
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PHOSPHOLIPASE A2 ENGINEERING. X-RAY STRUCTURAL AND FUNCTIONAL EVIDENCE FOR THE INTERACTION OF LYSINE-56 WITH SUBSTRATES
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sundaralingam, M.
Deposit date:1992-01-17
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Biochemistry, 30, 1991
2DO2
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BU of 2do2 by Molmil
Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution
Descriptor: Ala-Leu-Ala-Ser-Lys, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
Deposit date:2006-04-27
Release date:2006-05-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution
To be Published
2DPZ
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Structure of the complex of phospholipase A2 with N-(4-hydroxyphenyl)- acetamide at 2.1 A resolution
Descriptor: N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Sharma, S, Singh, T.P.
Deposit date:2006-05-18
Release date:2006-06-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phospholipase A2 as a target protein for non-steroidal anti-inflammatory drugs (NSAIDs): Crystal structure of the complex formed between a group II phospholipase A2 and N-(4-hydroxyphenyl) - acetamide at 2.1 resolution
To be Published
2FNX
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Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution
Descriptor: Inhibitor peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Srivastava, P, Sharma, S, Dey, S, Singh, T.P.
Deposit date:2006-01-11
Release date:2006-01-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Specific Peptide Inhibitors of Phospholipase A2 (PLA2): Crystal Structure of the Complex of PLA2 with a Highly Potent Peptide Val-Ile-Ala-Lys at 2.7A Resolution
To be Published
2G58
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Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution
Descriptor: (PHQ)IARS, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Prem Kumar, R, Singh, N, Somvanshi, R.K, Ethayathulla, A.S, Dey, S, Sharma, S, Kaur, P, Perbandt, M, Betzel, C, Singh, T.P.
Deposit date:2006-02-22
Release date:2006-03-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution
To be Published
2GNS
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Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala- Leu- Val- Tyr- Lys at 2.3 A resolution
Descriptor: ALVYK, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
Authors:Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
Deposit date:2006-04-11
Release date:2006-04-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design of specific peptide inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II phospholipase A2 and a designed pentapeptide Ala - Leu - Val - Tyr - Lys at 2.3 A resolution
To be Published
2H4C
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BU of 2h4c by Molmil
Structure of Daboiatoxin (heterodimeric PLA2 venom)
Descriptor: Phospholipase A2-II, Phospholipase A2-III
Authors:Gopalan, G, Thwin, M.M, Gopalakrishnakone, P, Swaminathan, K.
Deposit date:2006-05-24
Release date:2007-05-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and pharmacological comparison of daboiatoxin from Daboia russelli siamensis with viperotoxin F and vipoxin from other vipers.
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2H8I
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Crystal Structure of the Bothropstoxin-I complexed with polyethylene glycol
Descriptor: DI(HYDROXYETHYL)ETHER, Phospholipase A2 homolog 1
Authors:Murakami, M.T, Arni, R.K.
Deposit date:2006-06-07
Release date:2007-06-19
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49 PLA2 homologues
Toxicon, 49, 2007
2I0U
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BU of 2i0u by Molmil
Crystal structures of phospholipases A2 from Vipera nikolskii venom revealing Triton X-100 bound in hydrophobic channel
Descriptor: Basic subunit of heterodimer phospholipase A2, CALCIUM ION, FRAGMENT OF TRITON X-100, ...
Authors:Gao, W, Bi, R.C.
Deposit date:2006-08-11
Release date:2007-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of phospholipases A2 from Vipera nikolskii venom revealing Triton X-100 bound in hydrophobic channel
To be Published
2NOT
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BU of 2not by Molmil
NOTECHIS II-5, NEUROTOXIC PHOSPHOLIPASE A2 FROM NOTECHIS SCUTATUS SCUTATUS
Descriptor: PHOSPHOLIPASE A2
Authors:Carredano, E, Westerlund, B, Persson, B, Saarinen, M, Ramaswamy, S, Eaker, D, Eklund, H.
Deposit date:1997-03-03
Release date:1997-06-16
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2.
Toxicon, 36, 1998
2O1N
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Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution
Descriptor: Ala-Ile-Ala-Ser peptide, Phospholipase A2 VRV-PL-VIIIa
Authors:Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2006-11-29
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution
To be Published
2OK9
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PrTX-I-BPB
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog 1, p-Bromophenacyl bromide
Authors:Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.
Deposit date:2007-01-16
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity.
Biochim.Biophys.Acta, 1794, 2009
2OLI
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BU of 2oli by Molmil
Crystal structure of the complex formed between a group II phospholipase A2 and an indole derivative at 2.2 A resolution
Descriptor: INDOLYLPROPIONIC ACID, Phospholipase A2 VRV-PL-VIIIa
Authors:Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2007-01-19
Release date:2007-02-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of the complex formed between a group II phospholipase A2 and an indole derivative at 2.2 A resolution
To be Published
2OQD
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Crystal Structure of BthTX-II
Descriptor: Phospholipase A2
Authors:Correa, L.C, Marchi-Salvador, D.P, Cintra, A.C.O, Soares, A.M, Fontes, M.R.M.
Deposit date:2007-01-31
Release date:2008-02-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structure of a myotoxic Asp49-phospholipase A(2) with low catalytic activity: Insights into Ca(2+)-independent catalytic mechanism.
Biochim.Biophys.Acta, 1784, 2008
2OSH
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crystal structure of Natratoxin, a snake sPLA2 that blocks A-type K+ channel
Descriptor: Phospholipase A2 1
Authors:Teng, M.K, Sun, L.
Deposit date:2007-02-06
Release date:2007-03-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Natratoxin, a novel snake secreted phospholipaseA2 neurotoxin from Naja atra venom inhibiting A-type K+ currents.
Proteins, 72, 2008

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