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5SZW
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BU of 5szw by Molmil
NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR
Descriptor: ELAV-like protein 1
Authors:Lixa, C, Mujo, A, Jendiroba, K.A, Almeida, F.C.L, Lima, L.M.T.R, Pinheiro, A.S.
Deposit date:2016-08-15
Release date:2017-09-06
Last modified:2020-01-08
Method:SOLUTION NMR
Cite:Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.
J. Biomol. NMR, 72, 2018
5TBX
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BU of 5tbx by Molmil
hnRNP A18 RNA Recognition Motif
Descriptor: ACETATE ION, Cold-inducible RNA-binding protein, NICKEL (II) ION
Authors:Coburn, K.M, Melville, Z, Aligholizadeh, E, Roth, B.M, Varney, K.M, Weber, D.J.
Deposit date:2016-09-13
Release date:2017-04-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.767 Å)
Cite:Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5TKZ
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BU of 5tkz by Molmil
MEC-8 N-terminal RRM bound to tandem GCAC ligand
Descriptor: DNA (5'-D(*AP*GP*CP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*TP*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein
Authors:Soufari, H, Mackereth, C.D.
Deposit date:2016-10-10
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
5UZG
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BU of 5uzg by Molmil
Crystal structure of Glorund qRRM1 domain
Descriptor: AT27789p, GLYCEROL, SULFATE ION
Authors:Teramoto, T, Hall, T.M.T.
Deposit date:2017-02-26
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition.
Cell Rep, 19, 2017
5UZM
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Crystal structure of Glorund qRRM2 domain
Descriptor: AT27789p
Authors:Teramoto, T, Hall, T.M.T.
Deposit date:2017-02-27
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition.
Cell Rep, 19, 2017
5W0H
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Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5W0G
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Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5WWF
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BU of 5wwf by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5WWG
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Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5WWE
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BU of 5wwe by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
1O0P
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Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal SF1 peptide
Descriptor: Splicing Factor SF1, Splicing factor U2AF 65 kDa subunit
Authors:Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
Deposit date:2003-02-24
Release date:2003-05-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural Basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
1NO8
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BU of 1no8 by Molmil
SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN
Descriptor: ALY
Authors:Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E.
Deposit date:2003-01-15
Release date:2003-08-12
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional Regulatory and mRNA Nuclear Export Processes
Biochemistry, 42, 2003
1NU4
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BU of 1nu4 by Molmil
U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix
Descriptor: MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain
Authors:Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R.
Deposit date:2003-01-30
Release date:2003-02-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
1OIA
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BU of 1oia by Molmil
U1A rnp domain 1-95
Descriptor: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
Authors:Nagai, K, Evans, P.R.
Deposit date:2003-06-12
Release date:2003-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A
Nature, 348, 1990
1P1T
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BU of 1p1t by Molmil
NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
Descriptor: Cleavage stimulation factor, 64 kDa subunit
Authors:Perez-Canadillas, J.M, Varani, G.
Deposit date:2003-04-14
Release date:2003-08-12
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
Embo J., 22, 2003
1OPI
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BU of 1opi by Molmil
SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE
Descriptor: SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
Deposit date:2003-03-05
Release date:2004-03-16
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
1PGZ
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BU of 1pgz by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Moore, S.A, Shamoo, Y.
Deposit date:2003-05-28
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.Biol.Chem., 278, 2003
1PO6
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BU of 1po6 by Molmil
Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Descriptor: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Moore, S.A, Shamoo, Y.
Deposit date:2003-06-13
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.BIOL.CHEM., 278, 2003
1RKJ
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BU of 1rkj by Molmil
Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target
Descriptor: 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin
Authors:Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J.
Deposit date:2003-11-21
Release date:2004-04-27
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.
J.Mol.Biol., 337, 2004
1SJ3
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BU of 1sj3 by Molmil
Hepatitis Delta Virus Gemonic Ribozyme Precursor, with Mg2+ Bound
Descriptor: MAGNESIUM ION, precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A.
Deposit date:2004-03-02
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature, 429, 2004
1S79
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BU of 1s79 by Molmil
Solution structure of the central RRM of human La protein
Descriptor: Lupus La protein
Authors:Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R.
Deposit date:2004-01-29
Release date:2004-04-06
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Nat.Struct.Mol.Biol., 11, 2004
1SJF
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BU of 1sjf by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Cobalt Hexammine solution
Descriptor: COBALT HEXAMMINE(III), Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature, 429, 2004
7AAO
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BU of 7aao by Molmil
Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
Descriptor: U2 snRNP auxiliary factor large subunit
Authors:Kawale, A.A, Kang, H.S, Sattler, M.
Deposit date:2020-09-04
Release date:2021-10-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
To Be Published
7AEP
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BU of 7aep by Molmil
Solution structure of U1-A RRM2 (190-282)
Descriptor: U1 small nuclear ribonucleoprotein A
Authors:Campagne, S, Allain, F.H.
Deposit date:2020-09-18
Release date:2021-02-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands.
Nucleic Acids Res., 49, 2021
7CSZ
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BU of 7csz by Molmil
Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA
Descriptor: DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45
Authors:Chen, X, Yang, Z, Wang, W, Wang, M.
Deposit date:2020-08-17
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021

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