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1ARD
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BU of 1ard by Molmil
STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C, Xu, R.X, Horvath, S.J, Herriott, J.R, Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
1ARE
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BU of 1are by Molmil
STRUCTURES OF DNA-BINDING MUTANT ZINC FINGER DOMAINS: IMPLICATIONS FOR DNA BINDING
Descriptor: YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION
Authors:Hoffman, R.C, Xu, R.X, Horvath, S.J, Herriott, J.R, Klevit, R.E.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structures of DNA-binding mutant zinc finger domains: implications for DNA binding.
Protein Sci., 2, 1993
5WJQ
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BU of 5wjq by Molmil
mouseZFP568-ZnF2-11 in complex with DNA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (28-MER), ZINC ION, ...
Authors:Patel, A, Cheng, X.
Deposit date:2017-07-24
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
5YEG
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BU of 5yeg by Molmil
Crystal structure of CTCF ZFs4-8-Hs5-1a complex
Descriptor: DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3'), Transcriptional repressor CTCF, ...
Authors:Yin, M, Wang, J, Wang, M, Li, X.
Deposit date:2017-09-17
Release date:2017-11-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
5YJ3
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BU of 5yj3 by Molmil
Crystal structure of TZAP and telomeric DNA complex
Descriptor: DNA (5'-D(*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Telomere zinc finger-associated protein, ...
Authors:Li, F, Zhao, Y.
Deposit date:2017-10-07
Release date:2017-12-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.845 Å)
Cite:The 11th C2H2 zinc finger and an adjacent C-terminal arm are responsible for TZAP recognition of telomeric DNA.
Cell Res., 28, 2018
5YEL
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BU of 5yel by Molmil
Crystal structure of CTCF ZFs6-11-gb7CSE
Descriptor: DNA (26-MER), Transcriptional repressor CTCF, ZINC ION
Authors:Yin, M, Wang, J, Wang, M, Li, X, Wang, Y.
Deposit date:2017-09-18
Release date:2017-11-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
5YEH
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BU of 5yeh by Molmil
Crystal structure of CTCF ZFs4-8-eCBS
Descriptor: DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), Transcriptional repressor CTCF, ...
Authors:Yin, M, Wang, J, Wang, M, Li, X, Wang, Y.
Deposit date:2017-09-17
Release date:2017-11-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.328 Å)
Cite:Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
5YEF
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BU of 5yef by Molmil
Crystal structure of CTCF ZFs2-8-Hs5-1aE
Descriptor: DNA (27-MER), Transcriptional repressor CTCF, ZINC ION
Authors:Yin, M, Wang, J, Wang, M, Li, X, Wang, Y.
Deposit date:2017-09-17
Release date:2017-11-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.807 Å)
Cite:Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
6B0O
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BU of 6b0o by Molmil
Zinc finger Domain of WT1(-KTS form) with 12+1mer Oligonucleotide with 3' Triplet TGT
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*TP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-09-14
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
6B0P
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BU of 6b0p by Molmil
Zinc finger Domain of WT1(-KTS form) with 12+1mer Oligonucleotide with 3' Triplet GGT
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(P*AP*CP*CP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*GP*GP*AP*GP*GP*GP*T)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-09-14
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.077 Å)
Cite:Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
6B0Q
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BU of 6b0q by Molmil
Zinc finger Domain of WT1(-KTS form) with 13+1mer Oligonucleotide with 3' Triplet TGT
Descriptor: DNA (5'-D(P*AP*AP*CP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*GP*GP*AP*GP*TP*GP*TP*T)-3'), SULFATE ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-09-14
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
6B0R
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BU of 6b0r by Molmil
Zinc finger Domain of WT1(-KTS form) with M342R Mutation and 14+1mer Oligonucleotide with 3' Triplet TGG
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*AP*GP*GP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*CP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-09-14
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
6BLW
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BU of 6blw by Molmil
Zinc finger Domain of WT1(+KTS form) with M342R Mutation and 17+1mer Oligonucleotide with Triplet GGT
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*AP*CP*CP*CP*TP*CP*CP*CP*AP*TP*TP*TP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*AP*AP*AP*TP*GP*GP*GP*AP*GP*GP*GP*TP*T)-3'), ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-11-11
Release date:2018-01-03
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.835 Å)
Cite:Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018
8SSS
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BU of 8sss by Molmil
ZnFs 1-7 of CCCTC-binding factor (CTCF) Complexed with 23mer
Descriptor: 1,2-ETHANEDIOL, DNA Strand (23mer) I, DNA Strand (23mer) II, ...
Authors:Horton, J.R, Yang, J, Cheng, X.
Deposit date:2023-05-08
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8SSQ
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BU of 8ssq by Molmil
ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 35mer DNA 35-4
Descriptor: DNA (35-MER) Strand 2, DNA (35-MER) Strand I, SODIUM ION, ...
Authors:Horton, J.R, Yang, J, Cheng, X.
Deposit date:2023-05-08
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8SSR
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BU of 8ssr by Molmil
ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 35mer DNA 35-20
Descriptor: DNA (35-MER) Strand I, DNA (35-MER) Strand II, SODIUM ION, ...
Authors:Horton, J.R, Yang, J, Cheng, X.
Deposit date:2023-05-08
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8SST
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BU of 8sst by Molmil
ZnFs 1-7 of CCCTC-binding factor (CTCF) K365T Mutant Complexed with 23mer
Descriptor: 1,2-ETHANEDIOL, DNA Strand (23mer) I, DNA Strand (23mer) II, ...
Authors:Horton, J.R, Yang, J, Cheng, X.
Deposit date:2023-05-08
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8SSU
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BU of 8ssu by Molmil
ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 19mer DNA
Descriptor: 1,2-ETHANEDIOL, DNA (19-MER) Strand I, DNA (19-MER) Strand II, ...
Authors:Horton, J.R, Yang, J, Cheng, X.
Deposit date:2023-05-08
Release date:2023-08-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structures of CTCF-DNA complexes including all 11 zinc fingers.
Nucleic Acids Res., 51, 2023
8VG3
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BU of 8vg3 by Molmil
Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure
Descriptor: ZINC ION, Zinc finger protein 711
Authors:Rua, A.J, Alexandrescu, A.T.
Deposit date:2023-12-22
Release date:2024-01-17
Method:SOLUTION NMR
Cite:Formerly degenerate seventh zinc finger domain from transcription factor ZNF711 rehabilitated by experimental NMR structure
To Be Published
5K5H
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BU of 5k5h by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7 and DNA complex structure
Descriptor: DNA (5'-D(*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*G)-3'), Transcriptional repressor CTCF, ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-05-23
Release date:2017-05-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.108 Å)
Cite:Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KE8
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BU of 5ke8 by Molmil
mouse Klf4 E446P ZnF1-3 and MpG/MpG sequence DNA complex structure
Descriptor: DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-06-09
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5K5J
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BU of 5k5j by Molmil
Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212
Descriptor: ACETATE ION, DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-05-23
Release date:2017-05-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.287 Å)
Cite:Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Mol. Cell, 66, 2017
5KE9
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BU of 5ke9 by Molmil
mouse Klf4 E446P ZnF1-3 and TpG/CpA sequence DNA complex structure
Descriptor: DNA (5'-D(*GP*AP*GP*GP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*AP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-06-09
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.336 Å)
Cite:Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KEA
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BU of 5kea by Molmil
mouse Klf4 ZnF1-3 (E446D) and CpG/CpG sequence DNA complex structure: Form I
Descriptor: DNA (5'-D(*GP*AP*GP*GP*CP*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*CP*GP*CP*CP*TP*C)-3'), Krueppel-like factor 4, ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-06-09
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.458 Å)
Cite:Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic Acids Res., 44, 2016
5KL6
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BU of 5kl6 by Molmil
Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA
Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*CP*CP*CP*AP*CP*GP*C)-3'), Wilms tumor protein, ...
Authors:Hashimoto, H, Cheng, X.
Deposit date:2016-06-23
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
Nucleic Acids Res., 44, 2016

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