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6A4M
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BU of 6a4m by Molmil
Structure of urate oxidase from Bacillus subtilis 168
Descriptor: GLYCEROL, Uric acid degradation bifunctional protein PucL
Authors:Jiang, Y.Y.
Deposit date:2018-06-20
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Urate Oxidase from Bacillus Subtilis 168
Crystallography Reports, 64, 2019
4CW2
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BU of 4cw2 by Molmil
Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 2.5 kGy)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, URICASE
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-04-01
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4D17
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BU of 4d17 by Molmil
Crystal structure of cofactor-free urate oxidase in complex with its 5-peroxoisourate intermediate (X-ray dose, 106 kGy)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(HYDRO)PEROXOISOURATE, OXYGEN MOLECULE, ...
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-05-01
Release date:2014-11-05
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4CW3
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BU of 4cw3 by Molmil
Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 665 kGy)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, 9-METHYL URIC ACID, ...
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-04-01
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4D12
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BU of 4d12 by Molmil
Crystal Structure of Cofactor-free Urate Oxidase Anaerobically Complexed with Uric Acid
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, URIC ACID, URICASE
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-05-01
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4CW0
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BU of 4cw0 by Molmil
Crystal structure of cofactor-free urate oxidase anaerobically complexed with 9-methyl uric acid
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 9-METHYL URIC ACID, URICASE
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-03-31
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4CW6
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BU of 4cw6 by Molmil
Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 92 kGy)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, 9-METHYL URIC ACID, ...
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-04-01
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4D13
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BU of 4d13 by Molmil
Crystal structure of cofactor-free urate oxidase in complex with its 5-peroxoisourate intermediate (X-ray dose, 2.2 kGy)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(HYDRO)PEROXOISOURATE, URICASE
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-05-01
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4D19
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BU of 4d19 by Molmil
Crystal structure of cofactor-free urate oxidase in complex with its 5-peroxoisourate intermediate (X-ray dose, 1.75 MGy)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(HYDRO)PEROXOISOURATE, OXYGEN MOLECULE, ...
Authors:Bui, S, Steiner, R.A.
Deposit date:2014-05-01
Release date:2014-10-29
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase.
Angew. Chem. Int. Ed. Engl., 53, 2014
4MB8
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BU of 4mb8 by Molmil
Evolutionary history and metabolic insights of ancient mammalian uricases
Descriptor: ACETATE ION, Uricase
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2013-08-19
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4009 Å)
Cite:Evolutionary history and metabolic insights of ancient mammalian uricases.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N9S
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BU of 4n9s by Molmil
High resolution X-RAY STRUCTURE OF URATE OXIDASE IN COMPLEX WITH 8-HYDROXYXANTHINE
Descriptor: 8-hydroxy-3,9-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLYCEROL, ...
Authors:Oksanen, E, Blakeley, M.P, Budayova-Spano, M.
Deposit date:2013-10-21
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation.
Plos One, 9, 2014
4N9V
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BU of 4n9v by Molmil
High resolution x-ray structure of urate oxidase in complex with 8-azaxanthine
Descriptor: 8-AZAXANTHINE, CHLORIDE ION, GLYCEROL, ...
Authors:Oksanen, E, Blakeley, M.P, Budayova-Spano, M.
Deposit date:2013-10-21
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation.
Plos One, 9, 2014
4N3M
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BU of 4n3m by Molmil
Joint neutron/X-ray structure of urate oxidase in complex with 8-azaxanthine
Descriptor: 8-AZAXANTHINE, CHLORIDE ION, SODIUM ION, ...
Authors:Oksanen, E, Blakeley, M.P, Budayova-Spano, M.
Deposit date:2013-10-07
Release date:2014-02-05
Last modified:2018-06-13
Method:NEUTRON DIFFRACTION (1.919 Å), X-RAY DIFFRACTION
Cite:The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation.
Plos One, 9, 2014
4N9M
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BU of 4n9m by Molmil
Joint neutron/x-ray structure of urate oxidase in complex with 8-hydroxyxanthine
Descriptor: 8-hydroxy-3,9-dihydro-1H-purine-2,6-dione, CHLORIDE ION, SODIUM ION, ...
Authors:Oksanen, E, Blakeley, M.P, Budayova-Spano, M.
Deposit date:2013-10-21
Release date:2014-02-05
Last modified:2018-06-13
Method:NEUTRON DIFFRACTION (2.023 Å), X-RAY DIFFRACTION
Cite:The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation.
Plos One, 9, 2014
4OQC
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BU of 4oqc by Molmil
Urate OXIDASE CO-CRYSTALLIZED WITH AZIDE
Descriptor: AZIDE ION, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T.
Deposit date:2014-02-08
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Azide inhibition of urate oxidase.
Acta Crystallogr.,Sect.F, 70, 2014
4OP6
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BU of 4op6 by Molmil
Urate OXIDASE + 8-AZAXANTHINE UNDER 40 BARS OXYGEN
Descriptor: 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ...
Authors:Colloc'h, N, Prange, T.
Deposit date:2014-02-05
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Functional relevance of the internal hydrophobic cavity of urate oxidase.
Febs Lett., 588, 2014
4OP9
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BU of 4op9 by Molmil
Urate OXIDASE IN COMPLEX WITH 8-AZAXANTHINE
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T.
Deposit date:2014-02-05
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Functional relevance of the internal hydrophobic cavity of urate oxidase.
Febs Lett., 588, 2014
4POE
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BU of 4poe by Molmil
Urate oxidase co-crystallized with uric acid and azide
Descriptor: AZIDE ION, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T.
Deposit date:2014-02-25
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Azide inhibition of urate oxidase.
Acta Crystallogr.,Sect.F, 70, 2014
4PUV
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BU of 4puv by Molmil
URATE OXIDASE DI-AZIDE complex
Descriptor: AZIDE ION, SODIUM ION, Uricase
Authors:Colloc'h, N, Prange, T.
Deposit date:2014-03-14
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Azide inhibition of urate oxidase.
Acta Crystallogr.,Sect.F, 70, 2014
4PR8
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BU of 4pr8 by Molmil
URATE OXIDASE AZIDE URIC ACID TERNARY complex
Descriptor: AZIDE ION, SODIUM ION, URIC ACID, ...
Authors:Colloc'h, N, Prange, T.
Deposit date:2014-03-05
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Azide inhibition of urate oxidase.
Acta Crystallogr.,Sect.F, 70, 2014
3L9G
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BU of 3l9g by Molmil
Urate oxidase complexed with uric acid and chloride
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Prange, T, Colloc'h, N, Gabison, L.
Deposit date:2010-01-05
Release date:2010-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand.
Acta Crystallogr.,Sect.D, 66, 2010
3OBP
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BU of 3obp by Molmil
Anaerobic complex of urate oxidase with uric acid
Descriptor: SODIUM ION, URIC ACID, Uricase
Authors:Gabison, L, Chopard, C, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M, Prange, T.
Deposit date:2010-08-08
Release date:2011-06-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray, ESR, and quantum mechanics studies unravel a spin well in the cofactor-less urate oxidase.
Proteins, 79, 2011
3P9F
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BU of 3p9f by Molmil
Urate oxidase-azaxanthine-azide ternary complex
Descriptor: 8-AZAXANTHINE, AZIDE ION, SODIUM ION, ...
Authors:Gabison, L, Colloc'H, N, El Hajji, M, Castro, B, Chiadmi, M, Prange, T.
Deposit date:2010-10-17
Release date:2011-09-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Azide and cyanide have different inhibition modes of urate oxidase
To be Published
3P9O
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BU of 3p9o by Molmil
Aerobic ternary complex of urate oxidase with azide and chloride
Descriptor: AZIDE ION, CHLORIDE ION, SODIUM ION, ...
Authors:Gabison, L, Colloc'H, N, El Hajji, M, Castro, B, Chiadmi, M, Prange, T.
Deposit date:2010-10-18
Release date:2011-08-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Azide and Cyanide Show Different Inhibition Modes to Urate Oxidase
To be Published
3PK8
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BU of 3pk8 by Molmil
Urate oxidase under 0.5 MPa / 5 bars pressure of nitrous oxide
Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase
Authors:Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
Deposit date:2010-11-11
Release date:2011-04-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011

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