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7S5A
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Crystal structure of human chemokine CCL8
Descriptor: C-C motif chemokine 8
Authors:Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
Deposit date:2021-09-10
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
7STA
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X-ray Crystal Structure of Truncated Human Chemokine CCL19 (7-70)
Descriptor: C-C motif chemokine 19
Authors:Lewandowski, E.M, Kroeck, K, Chen, Y.
Deposit date:2021-11-12
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into Molecular Recognition by Human Chemokine CCL19.
Biochemistry, 61, 2022
7T1E
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Structure of monomeric and dimeric human CCL20
Descriptor: C-C motif chemokine 20, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Peterson, F.C, Riutta, S.J, Volkman, B.F.
Deposit date:2021-12-01
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.459 Å)
Cite:CCL20 and CCR6 in the pathogenesis and treatment of psoriasis and psoriatic arthritis
To Be Published
2L4N
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Solution Structure of the Chemokine CCL21
Descriptor: C-C motif chemokine 21
Authors:Veldkamp, C.T, Peterson, F.C, Love, M, Sandberg, J.L.
Deposit date:2010-10-10
Release date:2011-11-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of CCL21 and identification of a putative CCR7 binding site.
Biochemistry, 51, 2012
2MGS
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BU of 2mgs by Molmil
Solution structure of CXCL5
Descriptor: C-X-C motif chemokine 5
Authors:Sepuru, K, Rajarathnam, K.
Deposit date:2013-11-04
Release date:2014-04-02
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Solution Structure of CXCL5 - A Novel Chemokine and Adipokine Implicated in Inflammation and Obesity.
Plos One, 9, 2014
2MP1
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BU of 2mp1 by Molmil
Solution structure of the human chemokine CCL19
Descriptor: C-C motif chemokine 19
Authors:Veldkamp, C.T, Peterson, F.C, Gabel-Eissens, S.J, Gillitzer, M.L.
Deposit date:2014-05-09
Release date:2015-06-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of CCL19 and Identification of Overlapping CCR7 and PSGL-1 Binding Sites.
Biochemistry, 54, 2015
2MPM
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Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1
Descriptor: CCR3, Eotaxin
Authors:Millard, C.J, Ludeman, J.P, Canals, M, Bridgford, J.L, Hinds, M.G, Clayton, D.J, Christopoulos, A, Payne, R.J, Stone, M.J.
Deposit date:2014-05-26
Release date:2014-12-10
Method:SOLUTION NMR
Cite:Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1.
Structure, 22, 2014
2N54
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Solution structure of a disulfide stabilized XCL1 dimer
Descriptor: Lymphotactin
Authors:Tyler, R.C, Tuinstra, R.L, Peterson, F.F, Volkman, B.F.
Deposit date:2015-07-07
Release date:2015-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation.
Acs Chem.Biol., 10, 2015
2NWG
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BU of 2nwg by Molmil
Structure of CXCL12:heparin disaccharide complex
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1
Authors:Murphy, J.W, Cho, Y, Lolis, E.
Deposit date:2006-11-14
Release date:2007-02-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin
J.Biol.Chem., 282, 2007
2Q8T
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Crystal Structure of the CC chemokine CCL14
Descriptor: CCL14
Authors:Blain, K.Y.
Deposit date:2007-06-11
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural and Functional Characterization of CC Chemokine CCL14
Biochemistry, 46, 2007
2Q8R
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Structural and Functional Characterization of CC Chemokine CCL14
Descriptor: CCL14
Authors:Blain, K.Y.
Deposit date:2007-06-11
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural and Functional Characterization of CC Chemokine CCL14
Biochemistry, 46, 2007
2R3Z
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BU of 2r3z by Molmil
Crystal structure of mouse IP-10
Descriptor: Small-inducible cytokine B10
Authors:Jabeen, T, Leonard, P, Jamaluddin, H, Acharya, K.R.
Deposit date:2007-08-30
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of mouse IP-10, a chemokine
Acta Crystallogr.,Sect.D, 64, 2008
2RA4
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BU of 2ra4 by Molmil
Crystal Structure of Human Monocyte Chemoattractant Protein 4 (MCP-4/CCL13)
Descriptor: SULFATE ION, Small-inducible cytokine A13, trifluoroacetic acid
Authors:Lubkowski, J, Barinka, C.
Deposit date:2007-09-14
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of human monocyte chemoattractant protein 4 (MCP-4/CCL13).
Acta Crystallogr.,Sect.D, 64, 2008
2SDF
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BU of 2sdf by Molmil
SOLUTION NMR STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), 30 STRUCTURES
Descriptor: STROMAL CELL-DERIVED FACTOR-1
Authors:Crump, M.P, Rajarathnam, K, Clark-Lewis, I, Sykes, B.D.
Deposit date:1998-03-07
Release date:1998-06-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
EMBO J., 16, 1997
1HFG
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BU of 1hfg by Molmil
NMR solution structure of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus (minimized average structure).
Descriptor: VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II
Authors:Crump, M.P, Elisseeva, E, Gong, J.-H, Clark-Lewis, I, Sykes, B.D.
Deposit date:2000-12-01
Release date:2001-01-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure/Function of Human Herpesvirus-8 Mip-II (1-71) and the Antagonist N-Terminal Segment (1-10)
FEBS Lett., 489, 2001
1HRJ
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BU of 1hrj by Molmil
HUMAN RANTES, NMR, 13 STRUCTURES
Descriptor: HUMAN REGULATED UPON ACTIVATION NORMAL T-CELL EXPRESSED AND SECRETED
Authors:Chung, C, Cooke, R.M, Proudfoot, A.E.I, Wells, T.N.C.
Deposit date:1995-08-18
Release date:1996-10-14
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The three-dimensional solution structure of RANTES.
Biochemistry, 34, 1995
1HHV
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BU of 1hhv by Molmil
SOLUTION STRUCTURE OF VIRUS CHEMOKINE VMIP-II
Descriptor: VIRUS CHEMOKINE VMIP-II
Authors:Shao, W, Fernandez, E, Navenot, J.M, Wilken, J, Thompson, D.A, Pepiper, S, Schweitzer, B.I, Lolis, E.
Deposit date:1998-12-06
Release date:2003-09-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:CCR2 and CCR5 receptor-binding properties of herpesvirus-8 vMIP-II based on sequence analysis and its solution structure
Eur.J.Biochem., 268, 2001
1ICW
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BU of 1icw by Molmil
INTERLEUKIN-8, MUTANT WITH GLU 38 REPLACED BY CYS AND CYS 50 REPLACED BY ALA
Descriptor: INTERLEUKIN-8
Authors:Eigenbrot, C, Lowman, H.B, Chee, L, Artis, D.R.
Deposit date:1996-09-18
Release date:1997-03-12
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50AIL-8 at 2 A resolution.
Proteins, 27, 1997
1HUM
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BU of 1hum by Molmil
SOLUTION STRUCTURE OF THE CHEMOKINE HMIP-1BETA(SLASH)ACT-2 BY MULTI-DIMENSIONAL NMR: A NOVEL CHEMOKINE DIMER
Descriptor: HUMAN MACROPHAGE INFLAMMATORY PROTEIN 1 BETA
Authors:Clore, G.M, Lodi, P.J, Garrett, D.S, Gronenborn, A.M.
Deposit date:1994-01-31
Release date:1994-04-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR.
Science, 263, 1994
1HUN
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BU of 1hun by Molmil
SOLUTION STRUCTURE OF THE CHEMOKINE HMIP-1BETA(SLASH)ACT-2 BY MULTI-DIMENSIONAL NMR: A NOVEL CHEMOKINE DIMER
Descriptor: HUMAN MACROPHAGE INFLAMMATORY PROTEIN 1 BETA
Authors:Clore, G.M, Lodi, P.J, Garrett, D.S, Gronenborn, A.M.
Deposit date:1994-01-31
Release date:1994-04-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR.
Science, 263, 1994
1ILQ
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BU of 1ilq by Molmil
CXCR-1 N-TERMINAL PEPTIDE BOUND TO INTERLEUKIN-8 (MINIMIZED MEAN)
Descriptor: INTERLEUKIN-8 PRECURSOR, INTERLEUKIN-8 RECEPTOR A
Authors:Skelton, N.J, Quan, C, Lowman, H.
Deposit date:1998-12-17
Release date:1998-12-23
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structure of a CXC chemokine-receptor fragment in complex with interleukin-8.
Structure Fold.Des., 7, 1999
1J8I
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BU of 1j8i by Molmil
Solution Structure of Human Lymphotactin
Descriptor: Lymphotactin
Authors:Kuloglu, E.S, McCaslin, D.R, Markley, J.L, Pauza, C.D, Volkman, B.F.
Deposit date:2001-05-21
Release date:2001-10-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Monomeric solution structure of the prototypical 'C' chemokine lymphotactin.
Biochemistry, 40, 2001
1ILP
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BU of 1ilp by Molmil
CXCR-1 N-TERMINAL PEPTIDE BOUND TO INTERLEUKIN-8
Descriptor: C-X-C chemokine receptor type 1, Interleukin-8 (precursor)
Authors:Skelton, N.J, Quan, C, Lowman, H.
Deposit date:1998-12-16
Release date:1998-12-23
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structure of a CXC chemokine-receptor fragment in complex with interleukin-8.
Structure Fold.Des., 7, 1999
1IL8
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THREE-DIMENSIONAL STRUCTURE OF INTERLEUKIN 8 IN SOLUTION
Descriptor: INTERLEUKIN-8
Authors:Clore, G.M, Gronenborn, A.M.
Deposit date:1990-03-08
Release date:1991-01-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Three-dimensional structure of interleukin 8 in solution.
Biochemistry, 29, 1990
1IKL
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BU of 1ikl by Molmil
NMR study of monomeric human interleukin-8 (minimized average structure)
Descriptor: HUMAN INTERLEUKIN-8 (MONOMERIC)
Authors:Rajarathnam, K, Clark-Lewis, I, Sykes, B.D.
Deposit date:1995-08-03
Release date:1995-10-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:1H NMR solution structure of an active monomeric interleukin-8.
Biochemistry, 34, 1995

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