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7ZZ6	Cryo-EM structure of "CT-CT dimer" of Lactococcus lactis pyruvate carboxylase with acetyl-CoA Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ... Authors: Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. Deposit date: 2022-05-25 Release date: 2022-12-28 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.15 Å) Cite: CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase. Nat Commun, 13, 2022
3N6R	CRYSTAL STRUCTURE OF the holoenzyme of PROPIONYL-COA CARBOXYLASE (PCC) Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase, alpha subunit, ... Authors: Huang, C.S, Sadre-Bazzaz, K, Tong, L. Deposit date: 2010-05-26 Release date: 2010-08-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. Nature, 466, 2010
5MLK	Biotin dependent carboxylase AccA3 dimer from Mycobacterium tuberculosis (Rv3285) Descriptor: Acetyl-COA carboxylase Authors: Bennett, M.D, Hogbom, M. Deposit date: 2016-12-07 Release date: 2017-03-08 Last modified: 2017-05-17 Method: X-RAY DIFFRACTION (1.939 Å) Cite: Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis. FEBS Open Bio, 7, 2017
6CT0	Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex Descriptor: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Authors: Jiang, J, Baiesc, F.L, Hiromasa, Y, Yu, X, Hui, W.H, Dai, X, Roche, T.E, Zhou, Z.H. Deposit date: 2018-03-21 Release date: 2018-04-18 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex. Biochemistry, 57, 2018
5CSK	Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated Descriptor: Acetyl-CoA carboxylase Authors: Wei, J, Tong, L. Deposit date: 2015-07-23 Release date: 2015-10-28 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature, 526, 2015
4RCN	Structure and function of a single-chain, multi-domain long-chain acyl-coa carboxylase Descriptor: long-chain acyl-CoA carboxylase Authors: Tran, T.H, Tong, L. Deposit date: 2014-09-16 Release date: 2014-11-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase. Nature, 518, 2015
3BG5	Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Xiang, S, Tong, L. Deposit date: 2007-11-26 Release date: 2008-02-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol., 15, 2008
7BGJ	C. thermophilum Pyruvate Dehydrogenase Complex Core Descriptor: Acetyltransferase component of pyruvate dehydrogenase complex Authors: Tueting, C, Kastritis, P.L. Deposit date: 2021-01-07 Release date: 2021-02-10 Last modified: 2021-02-17 Method: ELECTRON MICROSCOPY (6.9 Å) Cite: Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts. Cell Rep, 34, 2021
5I8I	Crystal Structure of the K. lactis Urea Amidolyase Descriptor: Urea Amidolyase Authors: Zhao, J, Xiang, S. Deposit date: 2016-02-19 Release date: 2017-04-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (6.5 Å) Cite: Structure and function of urea amidolyase. Biosci. Rep., 38, 2018
8F41	3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered Descriptor: 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ... Authors: Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. Deposit date: 2022-11-10 Release date: 2023-01-11 Last modified: 2023-01-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
8F3D	3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered Descriptor: 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL Authors: Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. Deposit date: 2022-11-09 Release date: 2023-01-11 Last modified: 2023-01-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase. Structure, 31, 2023
7B9K	Cryo-EM structure of the dihydrolipoyl transacetylase cubic core of the E. coli pyruvate dehydrogenase complex including lipoyl domains Descriptor: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Authors: Skerlova, J, Stenmark, P. Deposit date: 2020-12-14 Release date: 2021-08-11 Last modified: 2021-10-06 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion. Nat Commun, 12, 2021
5KS8	Crystal structure of two-subunit pyruvate carboxylase from Methylobacillus flagellatus Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, MANGANESE (II) ION, PYRUVIC ACID, ... Authors: Choi, P.H, Tong, L. Deposit date: 2016-07-07 Release date: 2016-10-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.01 Å) Cite: A distinct holoenzyme organization for two-subunit pyruvate carboxylase. Nat Commun, 7, 2016
8SGZ	Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6) Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... Authors: Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. Deposit date: 2023-04-13 Release date: 2023-05-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
3HBL	Crystal Structure of S. aureus Pyruvate Carboxylase T908A Mutant Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Tong, L, Yu, L.P.C. Deposit date: 2009-05-04 Release date: 2009-06-30 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.71 Å) Cite: A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
8SGY	Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6) Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... Authors: Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. Deposit date: 2023-04-13 Release date: 2023-05-17 Method: ELECTRON MICROSCOPY (8.62 Å) Cite: CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
8SGX	Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6) Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... Authors: Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. Deposit date: 2023-04-13 Release date: 2023-05-17 Method: ELECTRON MICROSCOPY (10.3 Å) Cite: CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics. J Struct Biol X, 7, 2023
3HB9	Crystal Structure of S. aureus Pyruvate Carboxylase A610T Mutant Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Tong, L, Yu, L.P.C. Deposit date: 2009-05-04 Release date: 2009-06-30 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
6YBQ	Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... Authors: Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. Deposit date: 2020-03-17 Release date: 2020-10-28 Last modified: 2021-05-12 Method: ELECTRON MICROSCOPY (1.96 Å) Cite: A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
7OTT	Metabolon-embedded pyruvate dehydrogenase complex E2 core at near-atomic resolution Descriptor: Acetyltransferase component of pyruvate dehydrogenase complex Authors: Tueting, C, Kastritis, P.L. Deposit date: 2021-06-10 Release date: 2021-12-01 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction. Nat Commun, 12, 2021
3HO8	Crystal Structure of S. aureus Pyruvate Carboxylase in complex with Coenzyme A Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, MANGANESE (II) ION, ... Authors: Tong, L, Yu, L.P.C. Deposit date: 2009-06-01 Release date: 2009-06-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
6YBP	Propionyl-CoA carboxylase of Methylorubrum extorquens with bound CoA Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... Authors: Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. Deposit date: 2020-03-17 Release date: 2020-10-28 Last modified: 2021-05-12 Method: ELECTRON MICROSCOPY (3.48 Å) Cite: A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
7Q5Q	Protein community member oxoglutarate dehydrogenase complex E2 core from C. thermophilum Descriptor: Dihydrolipoyllysine-residue succinyltransferase Authors: Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. Deposit date: 2021-11-04 Release date: 2022-02-02 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (4.38 Å) Cite: Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
7Q5R	Protein community member pyruvate dehydrogenase complex E2 core from C. thermophilum Descriptor: Acetyltransferase component of pyruvate dehydrogenase complex Authors: Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. Deposit date: 2021-11-04 Release date: 2022-02-02 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
6ZLM	Dihydrolipoyllysine-residue acetyltransferase component of fungal pyruvate dehydrogenase complex with protein X bound Descriptor: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Pyruvate dehydrogenase X component Authors: Forsberg, B.O, Aibara, S, Howard, R.J, Mortezaei, N, Lindahl, E. Deposit date: 2020-06-30 Release date: 2020-09-23 Last modified: 2020-12-16 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex. Nat Commun, 11, 2020

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