4DMU
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4F1J
| Crystal structure of the MG2+ loaded VWA domain of plasmodium falciparum trap protein | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Pihlajamaa, T, Knuuti, J, Kajander, T, Sharma, A, Permi, P. | Deposit date: | 2012-05-07 | Release date: | 2013-01-30 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues. Biochem.J., 450, 2013
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4F1K
| Crystal structure of the MG2+ free VWA domain of plasmodium falciparum trap protein | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | Authors: | Pihlajamaa, T, Knuuti, J, Kajander, T, Sharma, A, Permi, P. | Deposit date: | 2012-05-07 | Release date: | 2013-01-30 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues. Biochem.J., 450, 2013
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3GXB
| Crystal structure of VWF A2 domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... | Authors: | Zhou, Y.F, Springer, T.A. | Deposit date: | 2009-04-02 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor. Proc.Natl.Acad.Sci.USA, 106, 2009
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3HI6
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3HXO
| Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding | Descriptor: | Aptamer ARC1172, von Willebrand factor | Authors: | Huang, R.H, Sadler, J.E, Fremont, D.H, Diener, J.L, Schaub, R.G. | Deposit date: | 2009-06-21 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1. Structure, 17, 2009
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3HXQ
| Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding | Descriptor: | Aptamer ARC1172, von Willebrand Factor | Authors: | Huang, R.H, Sadler, J.E, Fremont, D.H, Diener, J.L, Schaub, R.G. | Deposit date: | 2009-06-21 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.694 Å) | Cite: | A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1. Structure, 17, 2009
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3IBS
| Crystal structure of conserved hypothetical protein BatB from Bacteroides thetaiotaomicron | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Hattne, J, Bearden, J, Borek, D, Nakka, C, Sather, A, Joachimiak, A, Otwinowski, Z, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-16 | Release date: | 2009-08-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of conserved hypothetical protein BatB from Bacteroides thetaiotaomicron To be Published
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4HQK
| Crystal structure of Plasmodium falciparum TRAP, P4212 form | Descriptor: | SULFATE ION, Thrombospondin-related anonymous protein, TRAP | Authors: | Song, G, Koksal, A.C, Lu, C, Springer, T.A. | Deposit date: | 2012-10-25 | Release date: | 2012-12-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | Shape change in the receptor for gliding motility in Plasmodium sporozoites. Proc.Natl.Acad.Sci.USA, 109, 2012
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4IHK
| Crystal structure of the Collagen VI alpha3 N5 domain R1061Q | Descriptor: | Collagen alpha3(VI) | Authors: | Mikolajek, H, Becker, A.K.A, Paulsson, M, Wagener, R, Werner, J.M. | Deposit date: | 2012-12-19 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein Structure, 22, 2014
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4IGI
| Crystal structure of the Collagen VI alpha3 N5 domain | Descriptor: | Collagen alpha3(VI) | Authors: | Mikolajek, H, Becker, A.K.A, Paulsson, M, Wagener, R, Werner, J.M. | Deposit date: | 2012-12-17 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein Structure, 22, 2014
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4IXD
| X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution | Descriptor: | 4-(3-{4-[(3-aminopropyl)carbamoyl]phenyl}-1H-indazol-1-yl)-N-methylbenzamide, Integrin alpha-L, MAGNESIUM ION | Authors: | Kallen, J. | Deposit date: | 2013-01-25 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification and x-ray structure based investigation of an ICAM-1 binding enhancing small molecule activator of LFA-1 To be Published, 2013
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4JDU
| The crystal structure of an aerotolerance-related membrane protein from Bacteroides fragilis NCTC 9343 with multiple mutations to serines. | Descriptor: | Aerotolerance-related membrane protein, CALCIUM ION, FORMIC ACID | Authors: | Fan, Y, Tan, K, Bigelow, L, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-02-25 | Release date: | 2013-03-27 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | The crystal structure of an aerotolerance-related membrane protein from Bacteroides fragilis NCTC 9343 with multiple mutations to serines. To be Published
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1XDG
| X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution | Descriptor: | (1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBENZYL)-4-[2-(METHYLAMINO)-2-OXOETHYL]-2-OXO-1,3-OXAZINAN-6-YL}ETHYL)-3 ,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL (2R)-2-METHYLBUTANOATE, Integrin alpha-L, MAGNESIUM ION | Authors: | Weitz-Schmidt, G, Welzenbach, K, Dawson, J, Kallen, J. | Deposit date: | 2004-09-06 | Release date: | 2004-09-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo J.Biol.Chem., 279, 2004
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1XDD
| X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution | Descriptor: | 8-[2-((2S)-4-HYDROXY-1-{[5-(HYDROXYMETHYL)-6-METHOXY-2-NAPHTHYL]METHYL}-6-OXOPIPERIDIN-2-YL)ETHYL]-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL 2-METHYLBUTANOATE, Integrin alpha-L, MAGNESIUM ION | Authors: | Weitz-Schmidt, G, Welzenbach, K, Dawson, J, Kallen, J. | Deposit date: | 2004-09-06 | Release date: | 2004-09-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo J.Biol.Chem., 279, 2004
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1XUO
| X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution | Descriptor: | (2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHYL)-1,4-DIAZEPAN-1-YL]-N-METHYL-3-(2-NAPHTHYL)PROPANAMIDE, Integrin alpha-L, MAGNESIUM ION | Authors: | Wattanasin, S, Kallen, J, Myers, S, Guo, Q, Sabio, M, Ehrhardt, C, Albert, R, Hommel, U, Weckbecker, G, Welzenbach, K. | Deposit date: | 2004-10-26 | Release date: | 2005-10-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1 Bioorg.Med.Chem.Lett., 15, 2005
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7F49
| von Willebrand factor (VWF) A1 domain with BT-100 aptamer RNA | Descriptor: | BT-100, GLYCEROL, von Willebrand factor | Authors: | Zhu, S. | Deposit date: | 2021-06-18 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The development and characterization of a long acting anti-thrombotic von Willebrand factor (VWF) aptamer J Thromb Haemost., 18, 2020
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7EOW
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8CE9
| Crystal structure of human Cd11b I domain in C121 space group | Descriptor: | 1,2-ETHANEDIOL, Integrin alpha-M, SULFATE ION | Authors: | Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K. | Deposit date: | 2023-02-01 | Release date: | 2023-03-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystal structure of human Cd11b I domain in C121 space group To Be Published
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8CE6
| Crystal structure of human Cd11b I domain in P212121 space group | Descriptor: | CHLORIDE ION, GLYCEROL, Integrin alpha-M, ... | Authors: | Koekemoer, L, Williams, E, Ni, X, Gao, Q, Coker, J, MacLean, E.M, Wright, N.D, Marsden, B, Von Delft, F, Schwenzer, A, Midwood, K. | Deposit date: | 2023-02-01 | Release date: | 2023-03-22 | Last modified: | 2023-04-12 | Method: | X-RAY DIFFRACTION (1.582 Å) | Cite: | Crystal structure of human Cd11b I domain in P212121 space group To Be Published
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7KC3
| X-ray structure of Lfa-1 I domain collected at 273 K | Descriptor: | Integrin alpha-L, MAGNESIUM ION | Authors: | Woldeyes, R.A, Hallenbeck, K.K, Pfaff, S.J, Lee, G, Cortez, S.V, Kelly, M.J, Akassoglou, K, Arkin, M.R, Fraser, J.S. | Deposit date: | 2020-10-05 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins To Be Published
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7KC5
| X-ray structure of Lfa-1 I domain in complex with BMS-68852 collected at 273 K | Descriptor: | 6-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl]pyridine-3-carboxylic acid, Integrin alpha-L, MAGNESIUM ION | Authors: | Woldeyes, R.A, Hallenbeck, K.K, Pfaff, S.J, Lee, G, Cortez, S.V, Kelly, M.J, Akassoglou, K, Arkin, M.R, Fraser, J.S. | Deposit date: | 2020-10-05 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins To Be Published
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7KC6
| X-ray structure of Lfa-1 I domain in complex with Lovastatin collected at 273 K | Descriptor: | Integrin alpha-L, LOVASTATIN, MAGNESIUM ION | Authors: | Woldeyes, R.A, Hallenbeck, K.K, Pfaff, S.J, Lee, G, Cortez, S.V, Kelly, M.J, Akassoglou, K, Arkin, M.R, Fraser, J.S. | Deposit date: | 2020-10-05 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Divergent conformational dynamics controls allosteric ligand accessibility across evolutionarily related I-domain-containing integrins To Be Published
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1N3Y
| Crystal structure of the alpha-X beta2 integrin I domain | Descriptor: | Integrin alpha-X | Authors: | Vorup-Jensen, T, Ostermeier, C, Shimaoka, M, Hommel, U, Springer, T.A. | Deposit date: | 2002-10-30 | Release date: | 2003-02-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and allosteric regulation of the alpha X beta 2 integrin I domain. Proc.Natl.Acad.Sci.USA, 100, 2003
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1N9Z
| INTEGRIN ALPHA M I DOMAIN MUTANT | Descriptor: | Integrin alpha-M, MAGNESIUM ION | Authors: | McCleverty, C.J, Liddington, R.C. | Deposit date: | 2002-11-26 | Release date: | 2003-05-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies Biochem.J., 372, 2003
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