Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3FRP
DownloadVisualize
BU of 3frp by Molmil
Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb
Descriptor: CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ...
Authors:Krishnan, V, Narayana, S.V.L.
Deposit date:2009-01-08
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb.
Structure, 17, 2009
4A5W
DownloadVisualize
BU of 4a5w by Molmil
Crystal structure of C5b6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ...
Authors:Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P.
Deposit date:2011-10-28
Release date:2012-03-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9.
Cell Rep., 1, 2012
2I07
DownloadVisualize
BU of 2i07 by Molmil
Human Complement Component C3b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Janssen, B.J.C, Christodoulidou, A, McCarthy, A, Lambris, J.D, Gros, P.
Deposit date:2006-08-10
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
4D94
DownloadVisualize
BU of 4d94 by Molmil
Crystal Structure of TEP1r
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Le, B.V, Williams, M, Logarajah, S, Baxter, R.H.G.
Deposit date:2012-01-11
Release date:2012-10-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles.
Plos Pathog., 8, 2012
2ICE
DownloadVisualize
BU of 2ice by Molmil
CRIg bound to C3c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
7NYC
DownloadVisualize
BU of 7nyc by Molmil
cryoEM structure of 3C9-sMAC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Menny, A, Couves, E.C, Bubeck, D.
Deposit date:2021-03-22
Release date:2021-10-06
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
7NYD
DownloadVisualize
BU of 7nyd by Molmil
cryoEM structure of 2C9-sMAC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Menny, A, Couves, E.C, Bubeck, D.
Deposit date:2021-03-22
Release date:2021-10-06
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
7NOZ
DownloadVisualize
BU of 7noz by Molmil
Structure of the nanobody stablized properdin bound alternative pathway proconvertase C3b:FB:FP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 alpha chain, Complement C3 beta chain, ...
Authors:Lorenzen, J, Pedersen, D.V, Andersen, G.R.
Deposit date:2021-02-26
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure determination of an unstable macromolecular complex enabled by nanobody-peptide bridging.
Protein Sci., 31, 2022
2ICF
DownloadVisualize
BU of 2icf by Molmil
CRIg bound to C3b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ...
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
4E0S
DownloadVisualize
BU of 4e0s by Molmil
Crystal Structure of C5b-6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ...
Authors:Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
4RTD
DownloadVisualize
BU of 4rtd by Molmil
Escherichia coli alpha-2-macroglobulin activated by porcine elastase
Descriptor: Uncharacterized lipoprotein YfhM
Authors:Fyfe, C.D, Grinter, R, Roszak, A.W, Josts, I, Cogdell, R.J, Walker, D.
Deposit date:2014-11-14
Release date:2015-07-15
Last modified:2015-07-29
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment.
Acta Crystallogr.,Sect.D, 71, 2015
7S63
DownloadVisualize
BU of 7s63 by Molmil
Native-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha 2-Macroglobulin
Authors:Arimura, Y, Funabiki, H.
Deposit date:2021-09-13
Release date:2022-01-05
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Structural Mechanics of the Alpha-2-Macroglobulin Transformation.
J.Mol.Biol., 434, 2021
7S62
DownloadVisualize
BU of 7s62 by Molmil
Locally refined protomer structure of native-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha 2-macroglobulin
Authors:Arimura, Y, Funabiki, H.
Deposit date:2021-09-12
Release date:2022-01-05
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural Mechanics of the Alpha-2-Macroglobulin Transformation.
J.Mol.Biol., 434, 2021
7S64
DownloadVisualize
BU of 7s64 by Molmil
Intermediate-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer
Descriptor: Alpha 2-macroglobulin
Authors:Arimura, Y, Funabiki, H.
Deposit date:2021-09-13
Release date:2022-01-05
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (6.43 Å)
Cite:Structural Mechanics of the Alpha-2-Macroglobulin Transformation.
J.Mol.Biol., 434, 2021
2WII
DownloadVisualize
BU of 2wii by Molmil
Complement C3b in complex with factor H domains 1-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ...
Authors:Wu, J, Janssen, B.J.C, Gros, P.
Deposit date:2009-05-12
Release date:2009-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
2WIN
DownloadVisualize
BU of 2win by Molmil
C3 convertase (C3bBb) stabilized by SCIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ...
Authors:Wu, J, Janssen, B.J, Gros, P.
Deposit date:2009-05-13
Release date:2009-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
3NMS
DownloadVisualize
BU of 3nms by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement C3c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
Authors:Geisbrecht, B.V, Garcia, B.L.
Deposit date:2010-06-22
Release date:2010-08-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
4U48
DownloadVisualize
BU of 4u48 by Molmil
Crystal structure of Salmonella alpha-2-macroglobulin
Descriptor: Putative inner membrane lipoprotein
Authors:Wong, S.G, Dessen, A.
Deposit date:2014-07-23
Release date:2014-09-17
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity.
Nat Commun, 5, 2014
4U4J
DownloadVisualize
BU of 4u4j by Molmil
Crystal structure of Salmonella alpha-2-macroglobulin mutant Y1175G
Descriptor: Putative inner membrane lipoprotein
Authors:Wong, S.G, Dessen, A.
Deposit date:2014-07-23
Release date:2014-09-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity.
Nat Commun, 5, 2014
2XWJ
DownloadVisualize
BU of 2xwj by Molmil
Crystal Structure of Complement C3b in Complex with Factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ...
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-04
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
4U59
DownloadVisualize
BU of 4u59 by Molmil
Crystal structure of Salmonella alpha-2-macroglobulin reacted with methylamine
Descriptor: alpha-2-macroglobulin
Authors:Wong, S.G, Dessen, A.
Deposit date:2014-07-24
Release date:2014-09-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structure of a bacterial alpha 2-macroglobulin reveals mimicry of eukaryotic innate immunity.
Nat Commun, 5, 2014
2XWB
DownloadVisualize
BU of 2xwb by Molmil
Crystal Structure of Complement C3b in complex with Factors B and D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ...
Authors:Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
6RU5
DownloadVisualize
BU of 6ru5 by Molmil
human complement C3 in complex with the hC3Nb1 nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2019-05-27
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RUR
DownloadVisualize
BU of 6rur by Molmil
Structure of the SCIN stabilized C3bBb convertase bound to properdin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ...
Authors:Pedersen, D.V, Gadeberg, T.A.F, Andersen, G.R.
Deposit date:2019-05-29
Release date:2019-08-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10, 2019
6RQJ
DownloadVisualize
BU of 6rqj by Molmil
Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5, Complement inhibitor, ...
Authors:Reichhardt, M.P, Johnson, S, Lea, S.M.
Deposit date:2019-05-15
Release date:2020-01-08
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An inhibitor of complement C5 provides structural insights into activation.
Proc.Natl.Acad.Sci.USA, 117, 2020

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon