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3UGP	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT) Descriptor: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor Authors: Feklistov, A, Darst, S.A. Deposit date: 2011-11-02 Release date: 2011-12-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.697 Å) Cite: Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... Authors: Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. Deposit date: 2009-08-01 Release date: 2009-11-10 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (19.799999 Å) Cite: Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
3UGO	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT) Descriptor: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor Authors: Feklistov, A, Darst, S.A. Deposit date: 2011-11-02 Release date: 2011-12-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.096 Å) Cite: Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
8FTD	Structure of Escherichia coli CedA in complex with transcription initiation complex Descriptor: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... Authors: Liu, M, Vassyliev, N, Nudler, E. Deposit date: 2023-01-11 Release date: 2024-01-10 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
3LEV	HIV-1 antibody 2F5 in complex with epitope scaffold ES2 Descriptor: 2F5 ANTIBODY HEAVY CHAIN, 2F5 ANTIBODY LIGHT CHAIN, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D. Deposit date: 2010-01-15 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Elicitation of structure-specific antibodies by epitope scaffolds. Proc.Natl.Acad.Sci.USA, 107, 2010
3LES	2F5 Epitope scaffold ES2 Descriptor: RNA polymerase sigma factor, SULFATE ION Authors: Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Wyatt, R, Baker, D, Kwong, P.D. Deposit date: 2010-01-15 Release date: 2010-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Elicitation of structure-specific antibodies by epitope scaffolds. Proc.Natl.Acad.Sci.USA, 107, 2010
3WOD	RNA polymerase-gp39 complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S. Deposit date: 2013-12-26 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis for promoter specificity switching of RNA polymerase by a phage factor. Genes Dev., 28, 2014
5D4E	Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP Descriptor: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-08-07 Release date: 2016-07-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.08 Å) Cite: The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
5E17	T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7) Descriptor: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-09-29 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016
5IPN	SigmaS-transcription initiation complex with 4-nt nascent RNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Liu, B, Zuo, Y, Steitz, T.A. Deposit date: 2016-03-09 Release date: 2016-03-30 Last modified: 2016-06-22 Method: X-RAY DIFFRACTION (4.61 Å) Cite: Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
5IPL	SigmaS-transcription initiation complex with 4-nt nascent RNA Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Zuo, Y, Steitz, T.A. Deposit date: 2016-03-09 Release date: 2016-03-30 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
5I2D	Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Feng, Y, Zhang, Y, Ebright, R.H. Deposit date: 2016-02-08 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.405 Å) Cite: Structural basis of transcription activation. Science, 352, 2016
5E18	T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8) Descriptor: DNA (28-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-09-29 Release date: 2016-03-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016
4X8K	Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2 Descriptor: 1,2-ETHANEDIOL, RNA polymerase sigma factor SigA, RNA polymerase-binding protein RbpA, ... Authors: Hubin, E.A, Flack, J.E, Tabib-Salazar, A, Paget, M.S, Darst, S.A, Campbell, E.A. Deposit date: 2014-12-10 Release date: 2015-06-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.202 Å) Cite: Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA. Proc.Natl.Acad.Sci.USA, 112, 2015
5IPM	SigmaS-transcription initiation complex with 4-nt nascent RNA Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Liu, B, Zuo, Y, Steitz, T.A. Deposit date: 2016-03-09 Release date: 2016-03-30 Last modified: 2016-06-22 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
4XLS	Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter. Descriptor: CarD-like transcriptional regulator, DNA (30-MER), DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3'), ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.01 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
4XLR	Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA Descriptor: CarD-like transcriptional regulator, DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.3 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
4XLN	Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and RNA Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4 Å) Cite: Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
5H6X	The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila Descriptor: GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION Authors: Zhang, N, Chen, X, Gong, X, Ge, H. Deposit date: 2016-11-15 Release date: 2017-11-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila Crystals, 8, 2018
1OR7	Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA Descriptor: RNA polymerase sigma-E factor, Sigma-E factor negative regulatory protein Authors: Campbell, E.A, Tupy, J.L, Gruber, T.M, Wang, S, Sharp, M.M, Gross, C.A, Darst, S.A. Deposit date: 2003-03-12 Release date: 2003-04-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA. Mol.Cell, 11, 2003
1IW7	Crystal structure of the RNA polymerase holoenzyme from Thermus thermophilus at 2.6A resolution Descriptor: LEAD (II) ION, MAGNESIUM ION, RNA polymerase alpha subunit, ... Authors: RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2002-04-22 Release date: 2002-06-26 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution NATURE, 417, 2002
7P5X	Mycobacterial RNAP with transcriptional activator PafBC Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Mueller, A.U, Kummer, E, Schilling, C.M, Ban, N, Weber-Ban, E. Deposit date: 2021-07-15 Release date: 2021-12-22 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Transcriptional control of mycobacterial DNA damage response by sigma adaptation. Sci Adv, 7, 2021
7PP4	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-09-13 Release date: 2022-09-21 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Biorxiv, 2022
7Q59	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-11-03 Release date: 2022-11-16 Last modified: 2023-02-08 Method: ELECTRON MICROSCOPY (4.36 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
7Q4U	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme octamer comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-11-02 Release date: 2022-11-16 Last modified: 2023-02-08 Method: ELECTRON MICROSCOPY (4.39 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023

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