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6OIZ
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BU of 6oiz by Molmil
Amyloid-Beta (20-34) wild type
Descriptor: Amyloid beta A4 protein
Authors:Sawaya, M.R, Warmack, R.A, Zee, C.T, Gonen, T, Clarke, S.G, Eisenberg, D.S.
Deposit date:2019-04-10
Release date:2019-08-07
Last modified:2022-09-07
Method:ELECTRON CRYSTALLOGRAPHY (1.1 Å)
Cite:Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.
Nat Commun, 10, 2019
6OC9
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BU of 6oc9 by Molmil
S8 phosphorylated beta amyloid 40 fibrils
Descriptor: Amyloid-beta precursor protein, PHOSPHONATE
Authors:Qiang, W, Hu, Z.W.
Deposit date:2019-03-22
Release date:2019-06-05
Last modified:2020-01-01
Method:SOLID-STATE NMR
Cite:Molecular structure of an N-terminal phosphorylated beta-amyloid fibril.
Proc.Natl.Acad.Sci.USA, 116, 2019
1AMC
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BU of 1amc by Molmil
SOLUTION STRUCTURE OF RESIDUES 1-28 OF THE AMYLOID BETA-PEPTIDE
Descriptor: AMYLOID BETA-PEPTIDE
Authors:Talafous, J, Marcinowski, K.J, Klopman, G, Zagorski, M.G.
Deposit date:1994-11-14
Release date:1995-01-26
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of residues 1-28 of the amyloid beta-peptide.
Biochemistry, 33, 1994
1AMB
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BU of 1amb by Molmil
SOLUTION STRUCTURE OF RESIDUES 1-28 OF THE AMYLOID BETA-PEPTIDE
Descriptor: AMYLOID BETA-PEPTIDE
Authors:Talafous, J, Marcinowski, K.J, Klopman, G, Zagorski, M.G.
Deposit date:1994-10-21
Release date:1994-12-20
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of residues 1-28 of the amyloid beta-peptide.
Biochemistry, 33, 1994
1AML
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BU of 1aml by Molmil
THE ALZHEIMER`S DISEASE AMYLOID A4 PEPTIDE (RESIDUES 1-40)
Descriptor: AMYLOID A4
Authors:Roesch, P, Sticht, H.
Deposit date:1995-02-13
Release date:1996-01-29
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease.
Eur.J.Biochem., 233, 1995
1BA4
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BU of 1ba4 by Molmil
THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRANE-SPANNING DOMAIN WHERE WE THINK IT IS? NMR, 10 STRUCTURES
Descriptor: AMYLOID BETA-PEPTIDE
Authors:Coles, M, Bicknell, W, Watson, A.A, Fairlie, D.P, Craik, D.J.
Deposit date:1998-04-07
Release date:1998-06-17
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
Biochemistry, 37, 1998
8EZE
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BU of 8eze by Molmil
Brain-derived 42-residue amyloid-beta fibril type B
Descriptor: Beta-amyloid protein 42
Authors:Tycko, R, Lee, M, Yau, Y.-M, Louis, J.M.
Deposit date:2022-10-31
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EZD
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BU of 8ezd by Molmil
Brain-derived 42-residue amyloid-beta fibril type A
Descriptor: Beta-amyloid protein 42
Authors:Tycko, R, Lee, M, Yau, Y.-M, Louis, J.M.
Deposit date:2022-10-31
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions.
Proc.Natl.Acad.Sci.USA, 120, 2023
7E6P
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BU of 7e6p by Molmil
Fab-amyloid beta fragment complex
Descriptor: 1,2-ETHANEDIOL, Amyloid beta fragment with an intramolecular disulfide bond at positions 17 and 28, DI(HYDROXYETHYL)ETHER, ...
Authors:Kita, A, Irie, K, Irie, Y, Miki, K.
Deposit date:2021-02-23
Release date:2022-01-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization of a Conformation-Restricted Amyloid beta Peptide and Immunoreactivity of Its Antibody in Human AD brain.
Acs Chem Neurosci, 12, 2021
8FF2
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BU of 8ff2 by Molmil
Amyloid-beta (1-40) fibrils derived from a CAA patient
Descriptor: Amyloid-beta precursor protein
Authors:Crooks, E.J, Fu, Z, Chowdhury, S, Smith, S.O.
Deposit date:2022-12-07
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:An electrostatic cluster guides Abeta40 fibril formation in cerebral amyloid angiopathy
To Be Published
8FF3
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BU of 8ff3 by Molmil
Amyloid-beta (1-40) fibrils derived from familial Dutch-type CAA patient (population B)
Descriptor: Amyloid-beta precursor protein
Authors:Crooks, E.J, Fu, Z, Chowdury, S, Smith, S.O.
Deposit date:2022-12-07
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:An electrostatic cluster guides Abeta40 fibril formation in cerebral amyloid angiopathy
To Be Published
7F29
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BU of 7f29 by Molmil
Cryo-EM structure of the fibril formed by disaccharide-modified amyloid-beta(1-42)
Descriptor: ACETIC ACID, Amyloid-beta A4 protein, beta-D-galactopyranose-(1-3)-2-amino-2-deoxy-alpha-D-galactopyranose
Authors:Xia, W.C, Sun, Y.P, Liu, C.
Deposit date:2021-06-10
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:O-Glycosylation Induces Amyloid-beta To Form New Fibril Polymorphs Vulnerable for Degradation
J.Am.Chem.Soc., 143, 2021
7JXO
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BU of 7jxo by Molmil
Triangular trimer of beta-hairpins derived from Abeta17-36 with an F20Cha mutation
Descriptor: Amyloid-beta 17-36 peptide
Authors:Kreutzer, A.G, Haerianardakani, S, Nowick, J.S.
Deposit date:2020-08-27
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by beta-Hairpins Derived from A beta.
J.Am.Chem.Soc., 142, 2020
7JXN
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BU of 7jxn by Molmil
Beta hairpin derived from Abeta17-36 with an F20Cha mutation
Descriptor: Amyloid-beta 17-36 peptide, CHLORIDE ION, SODIUM ION
Authors:Kreutzer, A.G, Haerianardakani, S, Nowick, J.S.
Deposit date:2020-08-27
Release date:2020-12-09
Last modified:2020-12-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by beta-Hairpins Derived from A beta.
J.Am.Chem.Soc., 142, 2020
4ONG
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BU of 4ong by Molmil
Fab fragment of 3D6 in complex with amyloid beta 1-40
Descriptor: 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ...
Authors:Feinberg, H, Saldanha, J.W, Diep, L, Goel, A, Widom, A, Veldman, G.M, Weis, W.I, Schenk, D, Basi, G.S.
Deposit date:2014-01-28
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.
Alzheimers Res Ther, 6, 2014
2LLM
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BU of 2llm by Molmil
Structure of amyloid precursor protein's transmembrane domain
Descriptor: Amyloid beta A4 protein
Authors:Nadezhdin, K.D, Bocharova, O.V, Bocharov, E.V, Arseniev, A.S.
Deposit date:2011-11-15
Release date:2012-06-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and dynamic study of the transmembrane domain of the amyloid precursor protein.
Acta Naturae, 3, 2011
2LMP
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BU of 2lmp by Molmil
Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Positive Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Paravastu, A.
Deposit date:2011-12-08
Release date:2011-12-28
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils
Proc.Natl.Acad.Sci.USA, 105, 2008
2LMN
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BU of 2lmn by Molmil
Structural Model for a 40-Residue Beta-Amyloid Fibril with Two-Fold Symmetry, Positive Stagger
Descriptor: Beta-amyloid protein 40
Authors:Tycko, R, Petkova, A.
Deposit date:2011-12-08
Release date:2011-12-28
Last modified:2017-05-03
Method:SOLID-STATE NMR
Cite:Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils.
Proc. Natl. Acad. Sci. U.S.A., 105, 2008
6RHY
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BU of 6rhy by Molmil
Structure of pore-forming amyloid-beta tetramers
Descriptor: Amyloid beta A4 protein
Authors:Bardiaux, B, Ciudad, S, Carulla, N.
Deposit date:2019-04-23
Release date:2019-09-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A beta (1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage.
Nat Commun, 11, 2020
6SHS
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BU of 6shs by Molmil
Abeta fibril (Morphology I)
Descriptor: Amyloid-beta precursor protein
Authors:Kollmer, M, Fandrich, M.
Deposit date:2019-08-08
Release date:2019-11-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure and polymorphism of A beta amyloid fibrils purified from Alzheimer's brain tissue.
Nat Commun, 10, 2019
6SZF
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BU of 6szf by Molmil
Solution structure of the amyloid beta-peptide (1-42)
Descriptor: Amyloid-beta precursor protein
Authors:Grimaldi, M, Santoro, A, Stillitano, I, Buonocore, M, D'Ursi, A.M.
Deposit date:2019-10-02
Release date:2020-10-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Exploring the Early Stages of the Amyloid A beta (1-42) Peptide Aggregation Process: An NMR Study.
Pharmaceuticals, 14, 2021
6TI7
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BU of 6ti7 by Molmil
Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils
Descriptor: Amyloid-beta precursor protein
Authors:Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C.
Deposit date:2019-11-21
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLID-STATE NMR
Cite:Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56, 2020
6TI6
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BU of 6ti6 by Molmil
Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils
Descriptor: Amyloid-beta precursor protein
Authors:Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C.
Deposit date:2019-11-21
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLID-STATE NMR
Cite:Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56, 2020
6TI5
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BU of 6ti5 by Molmil
A New Structural Model of Abeta(1-40) Fibrils
Descriptor: Amyloid-beta precursor protein
Authors:Bertini, I, Gonnelli, L, Luchinat, C, Mao, J, Nesi, A.
Deposit date:2019-11-21
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLID-STATE NMR
Cite:Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils.
Chem.Commun.(Camb.), 56, 2020
6W0O
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BU of 6w0o by Molmil
Amyloid-beta(1-40) fibril derived from Alzheimer's disease cortical tissue
Descriptor: Amyloid-beta precursor protein
Authors:Ghosh, U, Thurber, K.R, Tycko, R.
Deposit date:2020-03-02
Release date:2021-01-13
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (2.77 Å), SOLID-STATE NMR
Cite:Molecular structure of a prevalent amyloid-beta fibril polymorph from Alzheimer's disease brain tissue.
Proc.Natl.Acad.Sci.USA, 118, 2021

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