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6EGR
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Crystal structure of Citrobacter freundii methionine gamma-lyase with V358Y replacement
Descriptor: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Revtovich, S.V, Demitri, N, Raboni, S, Nikulin, A.D, Morozova, E.A, Demidkina, T.V, Storici, P, Mozzarelli, A.
Deposit date:2017-09-12
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Engineering methionine gamma-lyase from Citrobacter freundii for anticancer activity.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
2NMP
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Crystal structure of human Cystathionine gamma lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van-den-Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2006-10-23
Release date:2006-11-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S
J.Biol.Chem., 284, 2009
2O7C
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Crystal structure of L-methionine-lyase from Pseudomonas
Descriptor: Methionine gamma-lyase, SULFATE ION
Authors:Misaki, S, Takimoto, A, Takakura, T, Yoshioka, T, Yamashita, M, Tamura, T, Tanaka, H, Inagaki, K.
Deposit date:2006-12-10
Release date:2007-12-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution
J.Biochem.(Tokyo), 141, 2007
4U1T
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BU of 4u1t by Molmil
The crystal structure of holo CalE6, a methionine gamma lyase from Micromonospora echinospora
Descriptor: CalE6, SULFATE ION
Authors:Song, H.G, Guo, Z.H.
Deposit date:2014-07-16
Release date:2015-01-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and Characterization of a Methionine gamma-Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora
Chembiochem, 16, 2015
4U2H
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The crystal structure of apo CalE6, a methionine gamma lyase from Micromonospora echinospora
Descriptor: CalE6, SULFATE ION
Authors:Song, H.G, Xu, R.
Deposit date:2014-07-17
Release date:2015-01-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification and Characterization of a Methionine gamma-Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora
Chembiochem, 16, 2015
7D7O
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BU of 7d7o by Molmil
Crystal structure of cystathionine gamma-lyase from Bacillus cereus ATCC 14579
Descriptor: Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Sagong, H.-Y, Kim, B, Kim, K.-J.
Deposit date:2020-10-05
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural and Functional Characterization of Cystathionine gamma-lyase from Bacillus cereus ATCC 14579.
J.Agric.Food Chem., 68, 2020
3JWB
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Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with norleucine
Descriptor: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, NORLEUCINE
Authors:Revtovish, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V.
Deposit date:2009-09-18
Release date:2010-09-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine gamma-lyase with substrates.
Biochemistry Mosc., 76, 2011
3JW9
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Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with S-ethyl-cysteine
Descriptor: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, S-ethyl-L-cysteine
Authors:Revtovish, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V.
Deposit date:2009-09-18
Release date:2010-09-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine gamma-lyase with substrates.
Biochemistry Mosc., 76, 2011
3VK4
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Crystal Structure of L-Methionine gamma-Lyase from Pseudomonas putida C116H Mutant complexed with L-homocysteine
Descriptor: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, Methionine gamma-lyase
Authors:Fukumoto, M, Kudou, D, Murano, S, Shiba, T, Sato, D, Tamura, T, Harada, S, Inagaki, K.
Deposit date:2011-11-07
Release date:2012-09-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:The role of amino acid residues in the active site of L-methionine gamma-lyase from Pseudomonas putida.
Biosci.Biotechnol.Biochem., 76, 2012
3VK3
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BU of 3vk3 by Molmil
Crystal Structure of L-Methionine gamma-Lyase from Pseudomonas putida C116H Mutant Complexed with L-methionine
Descriptor: METHIONINE, Methionine gamma-lyase
Authors:Fukumoto, M, Kudou, D, Murano, S, Shiba, T, Sato, D, Tamura, T, Harada, S, Inagaki, K.
Deposit date:2011-11-07
Release date:2012-09-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of amino acid residues in the active site of L-methionine gamma-lyase from Pseudomonas putida.
Biosci.Biotechnol.Biochem., 76, 2012
3JWA
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Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate
Descriptor: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID, DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase
Authors:Revtovish, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V.
Deposit date:2009-09-18
Release date:2010-09-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine gamma-lyase with substrates.
Biochemistry Mosc., 76, 2011
3VK2
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BU of 3vk2 by Molmil
Crystal Structure of L-Methionine gamma-Lyase from Pseudomonas putida C116H Mutant.
Descriptor: Methionine gamma-lyase, SULFATE ION
Authors:Fukumoto, M, Kudou, D, Murano, S, Shiba, T, Sato, D, Tamura, T, Harada, S, Inagaki, K.
Deposit date:2011-11-07
Release date:2012-09-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The role of amino acid residues in the active site of L-methionine gamma-lyase from Pseudomonas putida.
Biosci.Biotechnol.Biochem., 76, 2012
2RFV
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BU of 2rfv by Molmil
High resolution structure of L-methionine gamma-lyase from Citrobacter freundii
Descriptor: CHLORIDE ION, Methionine gamma-lyase
Authors:Nikulin, A.D, Revtovich, S.V, Morozova, E.A, Nevskaya, N.A, Nikonov, S.V, Garber, M.B, Demidkina, T.V.
Deposit date:2007-10-02
Release date:2008-08-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.355 Å)
Cite:High-resolution structure of methionine gamma-lyase from Citrobacter freundii.
Acta Crystallogr.,Sect.D, 64, 2008
8U98
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BU of 8u98 by Molmil
Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Glycine adduct)
Descriptor: 1,2-ETHANEDIOL, Cystathionine beta-lyase, GLYCINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Glycine adduct)
To be published
8U99
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BU of 8u99 by Molmil
Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Serine adduct)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cystathionine beta-lyase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-18
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Serine adduct)
To be published
1N8P
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Crystal Structure of cystathionine gamma-lyase from yeast
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
Authors:Messerschmidt, A, Worbs, M, Steegborn, C, Wahl, M.C, Huber, R, Clausen, T.
Deposit date:2002-11-21
Release date:2002-12-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Determinants of Enzymatic Specificity in the Cys-Met-Metabolism PLP-Dependent Enzymes Family: Crystal Structure of Cystathionine gamma-lyase from Yeast and Intrafamiliar Structural Comparison
BIOL.CHEM., 384, 2003
8WKR
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BU of 8wkr by Molmil
Crystal structure of O-acetylhomoserine sulfhydrylase from Lactobacillus plantarum in the open form
Descriptor: (2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid, L-methionine gamma-lyase, PROLINE
Authors:Oda, K, Matoba, Y.
Deposit date:2023-09-28
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Allosteric regulation of an acidophilic O-acetylhomoserine sulfhydrylase from Lactobacillus plantarum
To Be Published
8WKO
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Crystal structure of O-acetylhomoserine sulfhydrylase from Lactobacillus plantarum in the closed form
Descriptor: (2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid, L-methionine gamma-lyase, PROLINE, ...
Authors:Oda, K, Matoba, Y.
Deposit date:2023-09-28
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Allosteric regulation of an acidophilic O-acetylhomoserine sulfhydrylase from Lactobacillus plantarum
To Be Published
1IBJ
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BU of 1ibj by Molmil
Crystal structure of cystathionine beta-lyase from Arabidopsis thaliana
Descriptor: CARBONATE ION, CYSTATHIONINE BETA-LYASE, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Breitinger, U, Clausen, T, Messerschmidt, A.
Deposit date:2001-03-28
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity
Plant Physiol., 126, 2001
1I43
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BU of 1i43 by Molmil
CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR PPCA
Descriptor: 3-(PHOSPHONOMETHYL)PYRIDINE-2-CARBOXYLIC ACID, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
Deposit date:2001-02-19
Release date:2001-09-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
1I41
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BU of 1i41 by Molmil
CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR APPA
Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-IMINO]-5-PHOSPHONO-PENT-3-ENOIC ACID, CYSTATHIONINE GAMMA-SYNTHASE
Authors:Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
Deposit date:2001-02-19
Release date:2001-09-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
1I48
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CYSTATHIONINE GAMMA-SYNTHASE IN COMPLEX WITH THE INHIBITOR CTCPO
Descriptor: CARBOXYMETHYLTHIO-3-(3-CHLOROPHENYL)-1,2,4-OXADIAZOL, CYSTATHIONINE GAMMA-SYNTHASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Steegborn, C, Laber, B, Messerschmidt, A, Huber, R, Clausen, T.
Deposit date:2001-02-20
Release date:2001-09-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structures of cystathionine gamma-synthase inhibitor complexes rationalize the increased affinity of a novel inhibitor.
J.Mol.Biol., 311, 2001
5D5S
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BU of 5d5s by Molmil
Crystal structure of methionine gamma-lyase from Citrobacter freundii, S339A mutant
Descriptor: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Revtovich, S.V, Nikulin, A.D, Anufrieva, N.V, Morozova, E.A, Demidkina, T.V.
Deposit date:2015-08-11
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of methionine gamma-lyase from Citrobacter freundii, S339A mutant
To Be Published
1PFF
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Crystal Structure of Homocysteine alpha-, gamma-lyase at 1.8 Angstroms
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, methionine gamma-lyase
Authors:Allen, T.W, Sridhar, V, Prasad, S.G, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S.
Deposit date:2003-05-26
Release date:2004-08-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:

1PG8
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Crystal Structure of L-methionine alpha-, gamma-lyase
Descriptor: DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Allen, T.W, Sridhar, V, Prasad, G.S, Han, Q, Xu, M, Tan, Y, Hoffman, R.M, Ramaswamy, S.
Deposit date:2003-05-28
Release date:2004-06-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:
To Be Published

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