PDB: 67 resultsInfo pagesStatus searchChemie searchBIRD

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5V9G	Structure of the H477R variant of rat cytosolic PEPCK in complex with oxalate and GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V9H	Structure of the H477R variant of rat cytosolic PEPCK in complex with phosphoglycolate and GDP. Descriptor: 2-PHOSPHOGLYCOLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V95	Structure of the H477R variant of rat cytosolic PEPCK in complex with manganese. Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V9F	Structure of the H477R variant of rat cytosolic PEPCK in complex with beta sulfopyruvate and GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V97	Structure of the H477R variant of rat cytosolic PEPCK in complex with GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
1KHE	PEPCK complex with nonhydrolyzable GTP analog, MAD data Descriptor: MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Phosphoenolpyruvate Carboxykinase, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHB	PEPCK complex with nonhydrolyzable GTP analog, native data Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.854 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHG	PEPCK Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHF	PEPCK complex with PEP Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1M51	PEPCK complex with a GTP-competitive inhibitor Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... Authors: Foley, L.H, Wang, P, Dunten, P, Wertheimer, S.J. Deposit date: 2002-07-06 Release date: 2003-09-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.25 Å) Cite: X-ray Structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett., 13, 2003
5FH2	The structure of rat cytosolic PEPCK variant E89Q in complex with GTP Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2015-12-21 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH5	The structure of rat cytosolic PEPCK variant E89Q in complex with phosphoglycolate and GDP Descriptor: 2-PHOSPHOGLYCOLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2015-12-21 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH3	The structure of rat cytosolic PEPCK variant E89A in complex with oxalic acid and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2015-12-21 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH1	The structure of rat cytosolic PEPCK variant E89D in complex with GTP Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2015-12-21 Release date: 2016-12-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH0	The structure of rat cytosolic PEPCK variant E89A complex with GTP Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2015-12-21 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
5FH4	The structure of rat cytosolic PEPCK variant E89D in complex with beta-sulfopyruvate and GTP Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2015-12-21 Release date: 2016-11-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.49 Å) Cite: Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry, 55, 2016
4WPU	Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, PHOSPHOENOLPYRUVATE, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-21 Release date: 2015-11-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP To Be Published
4WL8	Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-06 Release date: 2015-10-21 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP to be published
4WOU	Crystal Structure of Mtb PEPCK in complex with GDP and metals Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Kim, H.L, Sacchettini, J.C. Deposit date: 2014-10-16 Release date: 2015-11-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.122 Å) Cite: Crystal Structure of Mtb PEPCK in complex with GDP and metals To Be Published
4YWD	Structure of rat cytosolic pepck in complex with 2,3-Pyridine dicarboxylic acid Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
4YW8	Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid Descriptor: 1,2-ETHANEDIOL, 3-sulfanylpyridine-2-carboxylic acid, MANGANESE (II) ION, ... Authors: Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
4YW9	Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and GTP Descriptor: 3-sulfanylpyridine-2-carboxylic acid, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
4YWB	Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and oxalic acid Descriptor: 3-sulfanylpyridine-2-carboxylic acid, CHLORIDE ION, MANGANESE (II) ION, ... Authors: Balan, M.D, Johnson, T.A, Lotosky, W.R, Mcleod, M.J, Holyoak, T. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
4GMZ	Structure of rat cytosolic PEPCK Ld_2g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GMM	Structure of rat cytosolic PEPCK Ld_1g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.736 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012

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