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8CFV
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Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H04
Descriptor: ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ...
Authors:Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K.
Deposit date:2023-02-03
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H04
To be published
8CFR
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BU of 8cfr by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment G03
Descriptor: 3-ethoxybenzene-1-carboximidamide, ADENINE, Adenosylhomocysteinase, ...
Authors:Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K.
Deposit date:2023-02-03
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry G03
To be published
8AZF
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BU of 8azf by Molmil
Crystal structure of K449E variant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with adenosine
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Arning, A, Malecki, P, Wozniak, K, Brzezinski, K.
Deposit date:2022-09-06
Release date:2023-09-13
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of K449E variant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with adenosine
To Be Published
8AJT
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BU of 8ajt by Molmil
Crystal structure of the H323A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, Adenosylhomocysteinase, ...
Authors:Drozdzal, P, Wozniak, K, Malecki, P, Gawel, M, Komorowska, M, Brzezinski, K.
Deposit date:2022-07-28
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Crystal structure of the H323A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
To Be Published
8AJW
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BU of 8ajw by Molmil
Crystal structure of the Q65N mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
Descriptor: ADENOSINE, DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Drozdzal, P, Wozniak, K, Malecki, P, Gawel, M, Komorowska, M, Brzezinski, K.
Deposit date:2022-07-28
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.819 Å)
Cite:Crystal structure of the Q65N mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
To Be Published
8AJV
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BU of 8ajv by Molmil
Crystal structure of the Q65N mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa crystallized in the presence of K+ cations
Descriptor: Adenosylhomocysteinase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Drozdzal, P, Wozniak, K, Malecki, P, Gawel, M, Komorowska, M, Brzezinski, K.
Deposit date:2022-07-28
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Q65N mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa crystallized in the presence of K+ cations
To Be Published
8AJS
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BU of 8ajs by Molmil
Crystal structure of the F324A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Drozdzal, P, Wozniak, K, Malecki, P, Gawel, M, Komorowska, M, Brzezinski, K.
Deposit date:2022-07-28
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of the F324A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
To Be Published
8AJU
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BU of 8aju by Molmil
Crystal structure of the Q65A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, GLYCEROL, ...
Authors:Drozdzal, P, Wozniak, K, Malecki, P, Gawel, M, Komorowska, M, Brzezinski, K.
Deposit date:2022-07-28
Release date:2023-08-16
Method:X-RAY DIFFRACTION (1.645 Å)
Cite:Crystal structure of the Q65A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
To Be Published
7ZD4
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BU of 7zd4 by Molmil
Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase soaked with Cu+ ions
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE, Adenosylhomocysteinase, ...
Authors:Malecki, P.H, Gawel, M, Brzezinski, K.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase soaked with Cu+ ions
To Be Published
7ZD2
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BU of 7zd2 by Molmil
Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Co2+ ions.
Descriptor: 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ...
Authors:Malecki, P.H, Gawel, M, Brzezinski, K.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Co2+ ions.
To Be Published
7ZD3
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BU of 7zd3 by Molmil
Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Zn2+ ions
Descriptor: 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ...
Authors:Malecki, P.H, Gawel, M, Brzezinski, K.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Zn2+ ions
To Be Published
7ZD0
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BU of 7zd0 by Molmil
Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Cd2+ ions
Descriptor: 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ...
Authors:Malecki, P.H, Gawel, M, Brzezinski, K.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Cd2+ ions
To Be Published
7ZD1
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BU of 7zd1 by Molmil
Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Hg2+ ions
Descriptor: 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ...
Authors:Malecki, P.H, Gawel, M, Brzezinski, K.
Deposit date:2022-03-29
Release date:2023-04-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Hg2+ ions
To Be Published
7R3A
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BU of 7r3a by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Methanococcus maripaludis in complex with inosine
Descriptor: INOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-inosyl-L-homocysteine hydrolase, ...
Authors:Saleem-Batcha, R, Popadic, D, Andexer, J.N.
Deposit date:2022-02-06
Release date:2023-02-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with inosine
To Be Published
7R37
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BU of 7r37 by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with inosine
Descriptor: Adenosylhomocysteinase, INOSINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Saleem-Batcha, R, Popadic, D, Andexer, J.N.
Deposit date:2022-02-06
Release date:2023-02-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with inosine
To Be Published
7R38
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BU of 7r38 by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with S-inosyl-L-homocysteine
Descriptor: (2S)-2-AMINO-4-({[(2S,3S,4R,5R)-3,4-DIHYDROXY-5-(6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)TETRAHYDROFURAN-2-YL]METHYL}THIO)BUTANOIC ACID, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Saleem-Batcha, R, Popadic, D, Andexer, J.N.
Deposit date:2022-02-06
Release date:2023-02-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pyrococcus furiosus in complex with S-inosyl-L-homocysteine
To Be Published
7R39
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BU of 7r39 by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Sulfolobus acidocaldarius in complex with adenosine
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Saleem-Batcha, R, Popadic, D, Andexer, J.N.
Deposit date:2022-02-06
Release date:2023-02-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of S-adenosyl-L-homocysteine hydrolase from Sulfolobus acidocaldarius in complex with adenosine
To Be Published
7ZD8
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BU of 7zd8 by Molmil
Crystal structure of the R24E mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K.
Deposit date:2022-03-29
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803.
Acta Crystallogr D Struct Biol, 78, 2022
7ZD7
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BU of 7zd7 by Molmil
Crystal structure of the R24E/E352T double mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K.
Deposit date:2022-03-29
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803.
Acta Crystallogr D Struct Biol, 78, 2022
7ZD9
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BU of 7zd9 by Molmil
Crystal structure of the E352T mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K.
Deposit date:2022-03-29
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803.
Acta Crystallogr D Struct Biol, 78, 2022
7O5M
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BU of 7o5m by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Na+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Malecki, P.H, Imiolczyk, B, Barciszewski, J, Czyrko-Horczak, J, Brzezinski, K.
Deposit date:2021-04-08
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803.
Acta Crystallogr D Struct Biol, 78, 2022
7O5L
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BU of 7o5l by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations
Descriptor: ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Malecki, P.H, Imiolczyk, B, Barciszewski, J, Czyrko-Horczak, J, Brzezinski, K.
Deposit date:2021-04-08
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803.
Acta Crystallogr D Struct Biol, 78, 2022
6UK3
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BU of 6uk3 by Molmil
Crystal Structure of S-adenosyl-L-homocysteine hydrolase from Acanthamoeba castellanii with bound NAD and Adenosine
Descriptor: ACETATE ION, ADENOSINE, Adenosylhomocysteinase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-10-04
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of S-adenosyl-L-homocysteine hydrolase from Acanthamoeba castellanii with bound NAD and Adenosine
to be published
6EXI
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BU of 6exi by Molmil
NAD-free crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii complexed with adenosine
Descriptor: ADENOSINE, Adenosylhomocysteinase, DI(HYDROXYETHYL)ETHER, ...
Authors:Manszewski, T, Jaskolski, M.
Deposit date:2017-11-08
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.918 Å)
Cite:S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic.
Front Microbiol, 9, 2018
6F3P
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BU of 6f3p by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with 3'-deoxyadenosine and K+ cation
Descriptor: 3'-DEOXYADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ...
Authors:Czyrko, J, Brzezinski, K.
Deposit date:2017-11-28
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa.
Sci Rep, 8, 2018

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PDB entries from 2024-04-17

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