PDB: 41 resultsInfo pagesStatus searchChemie searchBIRD

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1OWR	CRYSTAL STRUCTURE OF HUMAN NFAT1 BOUND MONOMERICALLY TO DNA Descriptor: NFAT1 Monomeric Binding Site, Minus Strand, Plus Strand, ... Authors: Stroud, J.C, Chen, L. Deposit date: 2003-03-29 Release date: 2004-02-10 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of NFAT Bound to DNA as a Monomer J.Mol.Biol., 334, 2003
1PZU	An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site Descriptor: 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', 5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... Authors: Jin, L, Sliz, P, Chen, L, Macian, F, Rao, A, Hogan, P.G, Harrison, S.C. Deposit date: 2003-07-14 Release date: 2003-09-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.1 Å) Cite: An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site Nat.Struct.Biol., 10, 2003
1RAM	A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65) Authors: Chen, Y.-Q, Ghosh, S, Ghosh, G. Deposit date: 1997-11-22 Release date: 1998-05-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A novel DNA recognition mode by the NF-kappa B p65 homodimer. Nat.Struct.Biol., 5, 1998
1SVC	NFKB P50 HOMODIMER BOUND TO DNA Descriptor: DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) Authors: Mueller, C.W, Harrison, S.C. Deposit date: 1995-11-27 Release date: 1996-06-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of the NF-kappa B p50 homodimer bound to DNA. Nature, 373, 1995
1IMH	TonEBP/DNA COMPLEX Descriptor: 5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3', 5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3', NUCLEAR FACTOR OF ACTIVATED T CELLS 5 Authors: Stroud, J.C, Lopez-Rodriguez, C, Rao, A, Chen, L. Deposit date: 2001-05-10 Release date: 2002-02-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor. Nat.Struct.Biol., 9, 2002
1LE5	Crystal structure of a NF-kB heterodimer bound to an IFNb-kB Descriptor: 5'-D(*AP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*T)-3', Nuclear factor NF-kappa-B p50 subunit, ... Authors: Berkowitz, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. Deposit date: 2002-04-09 Release date: 2003-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site J.Biol.Chem., 277, 2002
1LEI	The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription Descriptor: 5'-D(*CP*TP*CP*AP*GP*GP*GP*AP*AP*AP*GP*TP*AP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*5ITP*AP*CP*5ITP*5ITP*5ITP*CP*CP*CP*TP*GP*AP*G)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... Authors: Chen-Park, F, Huang, D.B, Ghosh, G. Deposit date: 2002-04-09 Release date: 2003-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The kB DNA sequence from the HIV Long Terminal Repeat functions as an allosteric regulator of HIV transcription J.Biol.Chem., 277, 2002
1LE9	Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti Descriptor: 5'-D(*AP*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*T)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... Authors: Benjamin, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. Deposit date: 2002-04-09 Release date: 2003-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. J.Biol.Chem., 277, 2002
1NFK	STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER Descriptor: DNA (5'-D(*TP*GP*GP*GP*AP*AP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) Authors: Ghosh, G, Van Duyne, G, Ghosh, S, Sigler, P.B. Deposit date: 1995-02-28 Release date: 1996-12-23 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of NF-kappa B p50 homodimer bound to a kappa B site. Nature, 373, 1995
5ZMC	Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 Descriptor: DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ... Authors: Xu, X, Bharath, S.R, Song, H. Deposit date: 2018-04-02 Release date: 2018-09-19 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1. Nat Commun, 9, 2018
2AS5	Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA. Descriptor: 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', 5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', Forkhead box protein P2, ... Authors: Wu, Y, Stroud, J.C, Borde, M, Bates, D.L, Guo, L, Han, A, Rao, A, Chen, L. Deposit date: 2005-08-22 Release date: 2006-08-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.7 Å) Cite: FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT. Cell(Cambridge,Mass.), 126, 2006
3QRF	Structure of a domain-swapped FOXP3 dimer Descriptor: Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ... Authors: Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L. Deposit date: 2011-02-17 Release date: 2011-04-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells. Immunity, 34, 2011
1A02	STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA Descriptor: AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ... Authors: Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C. Deposit date: 1997-12-08 Release date: 1998-05-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature, 392, 1998
1S9K	Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site Descriptor: Human IL-2 ARRE1 Promoter Element, Minus Strand, Plus Strand, ... Authors: Wang, D, Stroud, J.C, Chen, L. Deposit date: 2004-02-04 Release date: 2005-06-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site To be Published
1IKN	IKAPPABALPHA/NF-KAPPAB COMPLEX Descriptor: PROTEIN (I-KAPPA-B-ALPHA), PROTEIN (NF-KAPPA-B P50D SUBUNIT), PROTEIN (NF-KAPPA-B P65 SUBUNIT) Authors: Huxford, T, Huang, D.-B, Malek, S, Ghosh, G. Deposit date: 1998-11-13 Release date: 1999-04-12 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation. Cell(Cambridge,Mass.), 95, 1998
1NFI	I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX Descriptor: I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65 Authors: Jacobs, M.D, Harrison, S.C. Deposit date: 1998-08-25 Release date: 1998-11-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of an IkappaBalpha/NF-kappaB complex. Cell(Cambridge,Mass.), 95, 1998

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