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3LO2	Crystal structure of human alpha-defensin 1 (Y21A mutant) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Neutrophil defensin 1, SULFATE ION, ... Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LO1	Crystal structure of human alpha-defensin 1 (Y16A mutant) Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, AZIDE ION, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LOE	Crystal structure of human alpha-defensin 1 (F28A mutant) Descriptor: GLYCEROL, Neutrophil defensin 1, SULFATE ION Authors: Pazgier, M, Lu, W. Deposit date: 2010-02-03 Release date: 2010-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3I5W	Crystal structure of human alpha-defensin 5 (mutant R13H) Descriptor: CHLORIDE ION, CITRATE ANION, Defensin-5 Authors: Pazgier, M, Lu, W. Deposit date: 2009-07-06 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5 Febs Lett., 583, 2009
3HJD	X-ray structure of monomeric variant of HNP1 Descriptor: Human neutrophil peptide 1 Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2009-05-21 Release date: 2009-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: What Dictates the Multifaced Functions of the Human alpha-Defensin HNP? To be Published
3HJ2	Crystal structure of covalent dimer of HNP1 Descriptor: HUMAN NEUTROPHIL PEPTIDE 1 Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2009-05-20 Release date: 2009-10-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1? To be Published
3H6C	Crystal structure of human alpha-defensin 1 (Mutant Gln22Ala) Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W. Deposit date: 2009-04-23 Release date: 2010-03-09 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
2KHT	NMR Structure of human alpha defensin HNP-1 Descriptor: Neutrophil defensin 1 Authors: Zhang, Y, Li, S, Doherty, T.F, Lubkowski, J, Lu, W, Li, J, Barinka, C, Hong, M. Deposit date: 2009-04-11 Release date: 2010-02-09 Last modified: 2020-02-26 Method: SOLID-STATE NMR Cite: Resonance assignment and three-dimensional structure determination of a human alpha-defensin, HNP-1, by solid-state NMR. J.Mol.Biol., 397, 2010
3GNY	Crystal structure of human alpha-defensin 1 (HNP1) Descriptor: CHLORIDE ION, GLYCEROL, Neutrophil defensin 1 Authors: Pazgier, M, Lu, W.-Y. Deposit date: 2009-03-18 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Through the looking glass, mechanistic insights from enantiomeric human defensins. J.Biol.Chem., 284, 2009
2K1I	Synthesis, Structure and Activities of an Oral Mucosal Alpha-Defensin from Rhesus Macaque Descriptor: Mucosal Alpha-Defensin Authors: Vasudevan, S.V, Yuan, J, Osapay, G, Tran, P, Tai, K, Selsted, M, Cocco, M.J. Deposit date: 2008-03-05 Release date: 2008-10-28 Last modified: 2018-01-24 Method: SOLUTION NMR Cite: Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque. J.Biol.Chem., 283, 2008
2PM5	Human alpha-defensin 1 derivative (HNP1) Descriptor: Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1), PHOSPHATE ION Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2007-04-20 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Human alpha-defensin 1 derivative (HNP1) To be Published
2PM1	Derivative of human alpha-defensin 1 (HNP1) Descriptor: Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2007-04-20 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Derivative of human alpha-defensin 1 (HNP1) To be Published
2PM4	Human alpha-defensin 1 (multiple Arg->Lys mutant) Descriptor: Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) Authors: Lubkowski, J, Pazgier, M, Lu, W. Deposit date: 2007-04-20 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J.Biol.Chem., 282, 2007
1ZMH	Crystal structure of human neutrophil peptide 2, HNP-2 (variant Gly16-> D-Ala) Descriptor: GLYCEROL, HEXAETHYLENE GLYCOL, Neutrophil defensin 2, ... Authors: Lubkowski, J, Prahl, A, Lu, W. Deposit date: 2005-05-10 Release date: 2005-08-16 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280, 2005
1ZMI	Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group ) Descriptor: GLYCEROL, Neutrophil defensin 2, SULFATE ION Authors: Lubkowski, J, Prahl, A, Lu, W. Deposit date: 2005-05-10 Release date: 2005-08-16 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280, 2005
1ZMM	Crystal structure of human alpha-defensin-4 Descriptor: Neutrophil defensin 4 Authors: Lubkowski, J, Szyk, A, Lu, W. Deposit date: 2005-05-10 Release date: 2006-05-30 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6. Protein Sci., 15, 2006
1ZMK	Crystal structure of human alpha-defensin-2 (variant Gly16-> D-ALA), P 42 21 2 space group Descriptor: CHLORIDE ION, GLYCEROL, Neutrophil defensin 2 Authors: Lubkowski, J, Prahl, A, Lu, W. Deposit date: 2005-05-10 Release date: 2005-08-16 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280, 2005
1ZMP	Crystal structure of human defensin-5 Descriptor: CHLORIDE ION, Defensin 5, GLYCEROL, ... Authors: Lubkowski, J, Szyk, A, Lu, W. Deposit date: 2005-05-10 Release date: 2006-05-30 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6. Protein Sci., 15, 2006
1ZMQ	Crystal structure of human alpha-defensin-6 Descriptor: CHLORIDE ION, Defensin 6 Authors: Lubkowski, J, Szyk, A, Lu, W. Deposit date: 2005-05-10 Release date: 2006-05-30 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structures of human {alpha}-defensins HNP4, HD5, and HD6. Protein Sci., 15, 2006
1DFN	CRYSTAL STRUCTURE OF DEFENSIN HNP-3, AN AMPHIPHILIC DIMER: MECHANISMS OF MEMBRANE PERMEABILIZATION Descriptor: DEFENSIN HNP-3 Authors: Hill, C.P, Yee, J, Selsted, M.E, Eisenberg, D. Deposit date: 1991-01-18 Release date: 1992-07-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization. Science, 251, 1991

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