PDB: 198 resultsInfo pagesStatus searchChemie searchBIRD

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4RJ9	Structure of a plant specific C2 domain protein, OsGAP1 from rice Descriptor: C2 domain-containing protein-like, POTASSIUM ION Authors: Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M. Deposit date: 2014-10-08 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1). J.Biol.Chem., 290, 2015
4TS6	Crystal structure of the RIM C2A domain from Drosophila. Descriptor: GLYCEROL, Rab3 interacting molecule variant 2 Authors: Hatzopoulos, G.N, Shiroma, J, Vakonakis, I. Deposit date: 2014-06-18 Release date: 2015-07-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Crystal structure of the RIM C2A domain from Drosophila. To Be Published
3HN8	Crystal structure of synaptotagmin Descriptor: CALCIUM ION, Synaptotagmin-3, ZINC ION Authors: Strop, P, Vrljic, M, Ernst, J, Brunger, A.T. Deposit date: 2009-05-30 Release date: 2010-02-23 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat.Struct.Mol.Biol., 17, 2010
3TWY	RAT PKC C2 DOMAIN BOUND TO PB Descriptor: LEAD (II) ION, Protein kinase C alpha type, SULFATE ION Authors: Li, P. Deposit date: 2011-09-22 Release date: 2011-11-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Pb2+ as Modulator of Protein-Membrane Interactions. J.Am.Chem.Soc., 133, 2011
2Z0U	Crystal structure of C2 domain of KIBRA protein Descriptor: WW domain-containing protein 1 Authors: Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-05-07 Release date: 2008-05-13 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of C2 domain of KIBRA protein To be Published
2YOA	Synaptotagmin-1 C2B domain with phosphoserine Descriptor: CALCIUM ION, PHOSPHOSERINE, SYNAPTOTAGMIN-1, ... Authors: Honigmann, A, van den Bogaart, G, Iraheta, E, Risselada, H.J, Milovanovic, D, Mueller, V, Muellar, S, Diederichsen, U, Fasshauer, D, Grubmuller, H, Hell, S.W, Eggeling, C, Kuhnel, K, Jahn, R. Deposit date: 2012-10-22 Release date: 2013-03-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Phosphatidylinositol 4,5-Bisphosphate Clusters Act as Molecular Beacons for Vesicle Recruitment Nat.Struct.Mol.Biol., 20, 2013
3W56	Structure of a C2 domain Descriptor: C2 domain protein Authors: Traore, D.A.K, Whisstock, J.C. Deposit date: 2013-01-24 Release date: 2013-10-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
3L9B	Crystal Structure of Rat Otoferlin C2A Descriptor: MAGNESIUM ION, Otoferlin Authors: Helfmann, S, Neumann, P. Deposit date: 2010-01-04 Release date: 2011-01-19 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: The crystal structure of the C2A domain of otoferlin reveals an unconventional top loop region. J.Mol.Biol., 406, 2011
3W57	Structure of a C2 domain Descriptor: C2 domain protein, CALCIUM ION Authors: Traore, D.A.K, Whisstock, J.C. Deposit date: 2013-01-24 Release date: 2013-10-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.662 Å) Cite: Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
5H4Z	Crystal structure of S202G mutant of human SYT-5 C2A domain Descriptor: CALCIUM ION, CHLORIDE ION, Synaptotagmin-5 Authors: Qiu, X, Ge, J, Yan, X, Gao, Y, Teng, M, Niu, L. Deposit date: 2016-11-02 Release date: 2016-11-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain Int. J. Biol. Macromol., 95, 2017
5H4Y	Crystal structure of human synaptotagmin 5 C2A domain Descriptor: ACETATE ION, CALCIUM ION, Synaptotagmin-5 Authors: Qiu, X, Gao, Y, Teng, M, Niu, L. Deposit date: 2016-11-02 Release date: 2016-11-30 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain Int. J. Biol. Macromol., 95, 2017
8FAF	Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature Descriptor: Synaptotagmin Authors: McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B. Deposit date: 2022-11-26 Release date: 2023-07-19 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
8FAM	Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature Descriptor: Synaptotagmin Authors: McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. Deposit date: 2022-11-28 Release date: 2023-07-19 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Temperature-dependent RNA editing in octopus extensively recodes the neural proteome. Cell, 186, 2023
5LO8	The C2B domain of Rabphilin 3A in complex with PI(4,5)P2 Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ... Authors: Ferrer-Orta, C, Verdaguer, N. Deposit date: 2016-08-08 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural characterization of the Rabphilin-3A-SNAP25 interaction. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LOB	Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group) Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ... Authors: Ferrer-Orta, C, Verdaguer, N. Deposit date: 2016-08-09 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural characterization of the Rabphilin-3A-SNAP25 interaction. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LOW	Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group) Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ... Authors: Verdaguer, N, Ferrer-Orta, C. Deposit date: 2016-08-10 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural characterization of the Rabphilin-3A-SNAP25 interaction. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4ICX	N-terminal C2 domain of human CEP120 Descriptor: Centrosomal protein of 120 kDa Authors: Janowski, R, Guarin, N, Coll, M. Deposit date: 2012-12-11 Release date: 2014-06-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: N-terminal C2 domain tandem of human CEP120 shows lipid binding properties To be Published
4ICW	N-terminal C2 domain of human CEP120 Descriptor: Centrosomal protein of 120 kDa Authors: Janowski, R, Guarin, N, Coll, M. Deposit date: 2012-12-11 Release date: 2014-06-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: N-terminal C2 domain tandem of human CEP120 shows lipid binding properties To be Published
4IHB	X-RAY STRUCTURE OF THE canonical C2A DOMAIN FROM HUMAN DYSFERLIN Descriptor: CALCIUM ION, Dysferlin, FORMIC ACID Authors: Sutton, R.B, Fuson, K.L. Deposit date: 2012-12-18 Release date: 2013-12-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.044 Å) Cite: Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22, 2014
4IQH	Crystal Structure Analysis of Dysferlin C2A variant 1 (C2Av1) Descriptor: Dysferlin Authors: Sutton, R.B, Fuson, K.L. Deposit date: 2013-01-11 Release date: 2013-12-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.764 Å) Cite: Alternate Splicing of Dysferlin C2A Confers Ca(2+)-Dependent and Ca(2+)-Independent Binding for Membrane Repair. Structure, 22, 2014
1RH8	Three-dimensional structure of the calcium-free Piccolo C2A-domain Descriptor: Piccolo protein Authors: Garcia, J, Gerber, S.H, Sugita, S, Sudhof, T.C, Rizo, J. Deposit date: 2003-11-14 Release date: 2004-01-13 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: A conformational switch in the Piccolo C2A domain regulated by alternative splicing. Nat.Struct.Mol.Biol., 11, 2004
1RLW	CALCIUM-PHOSPHOLIPID BINDING DOMAIN FROM CYTOSOLIC PHOSPHOLIPASE A2 Descriptor: CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE A2 Authors: Perisic, O, Williams, R.L. Deposit date: 1997-10-28 Release date: 1998-02-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2. J.Biol.Chem., 273, 1998
1RSY	STRUCTURE OF THE FIRST C2-DOMAIN OF SYNAPTOTAGMIN I: A NOVEL CA2+(SLASH)PHOSPHOLIPID BINDING FOLD Descriptor: SULFATE ION, SYNAPTOTAGMIN I Authors: Sutton, R.B, Sprang, S.R. Deposit date: 1995-02-01 Release date: 1995-05-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold. Cell(Cambridge,Mass.), 80, 1995
4Y1S	Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes Descriptor: CALCIUM ION, Perforin-1 Authors: Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. Deposit date: 2015-02-09 Release date: 2015-09-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.611 Å) Cite: Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015
4Y1T	Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes Descriptor: CALCIUM ION, Perforin-1 Authors: Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. Deposit date: 2015-02-09 Release date: 2015-09-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.666 Å) Cite: Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015

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