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4X60
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BU of 4x60 by Molmil
Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin
Descriptor: GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2014-12-06
Release date:2015-04-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Nat.Chem.Biol., 11, 2015
2XU7
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BU of 2xu7 by Molmil
Structural basis for RbAp48 binding to FOG-1
Descriptor: HISTONE-BINDING PROTEIN RBBP4, TETRAETHYLENE GLYCOL, ZINC FINGER PROTEIN ZFPM1
Authors:Lejon, S, Thong, S.Y, Murthy, A, Blobel, G.A, Mackay, J.P, Murzina, N.V, Laue, E.D.
Deposit date:2010-10-15
Release date:2010-11-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights Into Association of the Nurd Complex with Fog-1 from the Crystal Structure of an Rbap48-Fog- 1 Complex.
J.Biol.Chem., 286, 2011
2PM7
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BU of 2pm7 by Molmil
Crystal structure of yeast Sec13/31 edge element of the COPII vesicular coat, selenomethionine version
Descriptor: Protein transport protein SEC13, Protein transport protein SEC31
Authors:Goldberg, J, Fath, S, Mancias, J.D, Bi, X.
Deposit date:2007-04-20
Release date:2007-07-03
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure and Organization of Coat Proteins in the COPII Cage.
Cell(Cambridge,Mass.), 129, 2007
4X61
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BU of 4x61 by Molmil
Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM
Descriptor: GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2014-12-06
Release date:2015-04-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Nat.Chem.Biol., 11, 2015
2YBA
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BU of 2yba by Molmil
Crystal structure of Nurf55 in complex with histone H3
Descriptor: HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1
Authors:Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
Deposit date:2011-03-02
Release date:2011-05-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
2PM6
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BU of 2pm6 by Molmil
Crystal Structure of yeast Sec13/31 edge element of the COPII vesicular coat, native version
Descriptor: Protein transport protein SEC13, Protein transport protein SEC31
Authors:Goldberg, J, Fath, S, Mancias, J.D, Bi, X.
Deposit date:2007-04-20
Release date:2007-07-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure and Organization of Coat Proteins in the COPII Cage.
Cell(Cambridge,Mass.), 129, 2007
2YB8
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BU of 2yb8 by Molmil
Crystal structure of Nurf55 in complex with Su(z)12
Descriptor: POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
Authors:Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
Deposit date:2011-03-02
Release date:2011-05-18
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
4N14
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BU of 4n14 by Molmil
Crystal structure of Cdc20 and apcin complex
Descriptor: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl [(1R)-2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate, Cell division cycle protein 20 homolog
Authors:Luo, X, Tian, W, Yu, H.
Deposit date:2013-10-03
Release date:2014-08-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.
Nature, 514, 2014
2YNP
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BU of 2ynp by Molmil
yeast betaprime COP 1-604 with KTKTN motif
Descriptor: COATOMER SUBUNIT BETA', KTKTN MOTIF
Authors:Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J.
Deposit date:2012-10-17
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.962 Å)
Cite:Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi.
Dev.Cell, 23, 2012
2QXV
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BU of 2qxv by Molmil
Structural basis of EZH2 recognition by EED
Descriptor: Embryonic ectoderm development, Enhancer of zeste homolog 2
Authors:Han, Z.
Deposit date:2007-08-13
Release date:2007-08-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural basis of EZH2 recognition by EED
Structure, 15, 2007
4OZU
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BU of 4ozu by Molmil
Crystal Structure of WD40 domain from Toxoplasma gondii coronin
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Coronin
Authors:Kallio, J.P, Kursula, I.
Deposit date:2014-02-19
Release date:2014-08-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of Toxoplasma gondii coronin, an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress.
Faseb J., 28, 2014
4OWR
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BU of 4owr by Molmil
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair Rae1-Nup98
Descriptor: Matrix protein, Nuclear pore complex protein Nup98-Nup96, mRNA export factor
Authors:Ren, Y, Quan, B, Seo, H.S, Blobel, G.
Deposit date:2014-02-03
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 Nup98).
Proc.Natl.Acad.Sci.USA, 111, 2014
2TRC
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BU of 2trc by Molmil
PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
Descriptor: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN
Authors:Gaudet, R, Bohm, A, Sigler, P.B.
Deposit date:1997-01-06
Release date:1997-06-05
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
4PBZ
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BU of 4pbz by Molmil
Structure of the human RbAp48-MTA1(670-695) complex
Descriptor: Histone-binding protein RBBP4, Metastasis-associated protein MTA1
Authors:Murthy, A, Pei, X.Y, Watson, A.A, Silva, A.P.G, Mackay, J.P, Laue, E.D.
Deposit date:2014-04-14
Release date:2014-06-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex.
J.Biol.Chem., 289, 2014
4PSX
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BU of 4psx by Molmil
Crystal structure of histone acetyltransferase complex
Descriptor: COENZYME A, Histone H3, Histone H4, ...
Authors:Yang, M, Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
3AH8
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BU of 3ah8 by Molmil
Structure of heterotrimeric G protein Galpha-q beta gamma in complex with an inhibitor YM-254890
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Nishimura, A, Kitano, K, Takasaki, J, Taniguchi, M, Mizuno, N, Tago, K, Hakoshima, T, Itoh, H.
Deposit date:2010-04-20
Release date:2010-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
4PBY
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BU of 4pby by Molmil
Structure of the human RbAp48-MTA1(656-686) complex
Descriptor: Histone-binding protein RBBP4, ISOPROPYL ALCOHOL, Metastasis-associated protein MTA1
Authors:Murthy, A, Lejon, S, Alqarni, S.S.M, Silva, A.P.G, Watson, A.A, Mackay, J.P, Laue, E.D.
Deposit date:2014-04-14
Release date:2014-06-11
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex.
J.Biol.Chem., 289, 2014
4PC0
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BU of 4pc0 by Molmil
Structure of the human RbAp48-MTA1(670-711) complex
Descriptor: CALCIUM ION, GLYCEROL, Histone-binding protein RBBP4, ...
Authors:Alqarni, S.S.M, Silva, A.P.G, Mackay, J.P, Laue, E.D.
Deposit date:2014-04-14
Release date:2014-06-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insight into the architecture of the NuRD complex: Structure of the RbAp48-MTA1 sub-complex.
J.Biol.Chem., 289, 2014
4PSW
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BU of 4psw by Molmil
Crystal structure of histone acetyltransferase complex
Descriptor: COENZYME A, Histone H4 type VIII, Histone acetyltransferase type B catalytic subunit, ...
Authors:Yang, M, Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
3BG1
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BU of 3bg1 by Molmil
Architecture of a Coat for the Nuclear Pore Membrane
Descriptor: Nucleoporin NUP145, Protein SEC13 homolog
Authors:Hoelz, A.
Deposit date:2007-11-23
Release date:2008-01-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Architecture of a coat for the nuclear pore membrane.
Cell(Cambridge,Mass.), 131, 2007
3BG0
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BU of 3bg0 by Molmil
Architecture of a Coat for the Nuclear Pore Membrane
Descriptor: Nucleoporin NUP145, Protein SEC13 homolog
Authors:Hoelz, A.
Deposit date:2007-11-23
Release date:2008-01-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Architecture of a coat for the nuclear pore membrane.
Cell(Cambridge,Mass.), 131, 2007
3C99
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BU of 3c99 by Molmil
Structural Basis of Histone H4 Recognition by p55
Descriptor: CADMIUM ION, Chromatin assembly factor 1 p55 subunit
Authors:Song, J.J, Garlick, J.D, Kingston, R.E.
Deposit date:2008-02-15
Release date:2008-05-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
4R7A
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BU of 4r7a by Molmil
Crystal Structure of RBBP4 bound to PHF6 peptide
Descriptor: GLYCEROL, Histone-binding protein RBBP4, PHD finger protein 6
Authors:Liu, Z, Li, F, Zhang, B, Li, S, Wu, J, Shi, Y.
Deposit date:2014-08-27
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex
J.Biol.Chem., 290, 2015
3C9C
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BU of 3c9c by Molmil
Structural Basis of Histone H4 Recognition by p55
Descriptor: CADMIUM ION, Chromatin assembly factor 1 p55 subunit, Histone H4, ...
Authors:Song, J.J, Garlick, J.D, Kingston, R.E.
Deposit date:2008-02-15
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
3V7D
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BU of 3v7d by Molmil
Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex
Descriptor: Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1
Authors:Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M.
Deposit date:2011-12-20
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109, 2012

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