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6GSM
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BU of 6gsm by Molmil
Structure of a partial yeast 48S preinitiation complex in open conformation.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6GML
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BU of 6gml by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF
Descriptor: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Vos, S.M, Farnung, L, Urlaub, H, Cramer, P.
Deposit date:2018-05-27
Release date:2018-09-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
6GD3
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BU of 6gd3 by Molmil
Structure of HuR RRM3 in complex with RNA (UAUUUA)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3'), SODIUM ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GD2
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BU of 6gd2 by Molmil
Structure of HuR RRM3 in complex with RNA
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3')
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GD1
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BU of 6gd1 by Molmil
Structure of HuR RRM3
Descriptor: SODIUM ION, Thioredoxin 1,ELAV-like protein 1
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6GC5
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BU of 6gc5 by Molmil
Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM
Descriptor: AU-rich RNA, ELAV-like protein 1
Authors:Ripin, N, Allain, F.H.
Deposit date:2018-04-17
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GBM
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BU of 6gbm by Molmil
Solution structure of FUS-RRM bound to stem-loop RNA
Descriptor: RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS
Authors:Loughlin, F.E, Allain, F.H.-T.
Deposit date:2018-04-15
Release date:2019-02-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell, 73, 2019
6G90
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BU of 6g90 by Molmil
Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ...
Authors:Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K.
Deposit date:2018-04-10
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Prespliceosome structure provides insights into spliceosome assembly and regulation.
Nature, 559, 2018
6G2K
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BU of 6g2k by Molmil
Structure of HuR RRM3 in complex with RNA (UUUUUU)
Descriptor: ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), SULFATE ION
Authors:Pabis, M, Sattler, M.
Deposit date:2018-03-23
Release date:2018-10-31
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6FYY
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BU of 6fyy by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYX
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BU of 6fyx by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FQR
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BU of 6fqr by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (CCCC)
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 3, RNA CCCC
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-14
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6FQ1
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BU of 6fq1 by Molmil
Crystal structure of the RRM12 domain of IMP3
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3
Authors:Jia, M, Gut, H, Chao, A.J.
Deposit date:2018-02-12
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
6FF7
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BU of 6ff7 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2019-03-13
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
6FF4
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BU of 6ff4 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2018-08-29
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
6FEC
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BU of 6fec by Molmil
Human cap-dependent 48S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schaffitzel, C, Schaffitzel, C.
Deposit date:2017-12-31
Release date:2018-03-14
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structure of a human cap-dependent 48S translation pre-initiation complex.
Nucleic Acids Res., 46, 2018
6F4J
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BU of 6f4j by Molmil
Crystal structure of Drosophila melanogaster SNF/U2A' complex
Descriptor: POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ...
Authors:Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4I
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BU of 6f4i by Molmil
Crystal structure of Drosophila melanogaster SNF
Descriptor: U1 small nuclear ribonucleoprotein A
Authors:Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4H
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BU of 6f4h by Molmil
Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex
Descriptor: CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2
Authors:Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6F4G
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BU of 6f4g by Molmil
'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex
Descriptor: CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ...
Authors:Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C.
Deposit date:2017-11-29
Release date:2018-06-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.
Nat Commun, 9, 2018
6EZ7
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BU of 6ez7 by Molmil
Pes4 RRM3 Structure
Descriptor: DI(HYDROXYETHYL)ETHER, Protein PES4
Authors:Mohamad, N, Bravo, J.
Deposit date:2017-11-14
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Pes4 RRM3 Structure
To Be Published
6EXN
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BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
Authors:Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
Deposit date:2017-11-08
Release date:2018-01-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
6ES4
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BU of 6es4 by Molmil
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ...
Authors:Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A.
Deposit date:2017-10-19
Release date:2018-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.
Nat Commun, 9, 2018
6EM5
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BU of 6em5 by Molmil
State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6EM4
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BU of 6em4 by Molmil
State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Last modified:2018-03-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017

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