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1WMS
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BU of 1wms by Molmil
High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-9A
Authors:Chen, L, DiGiammarino, E, Zhou, X.E, Wang, Y, Toh, D, Hodge, T.W, Meehan, E.J.
Deposit date:2004-07-16
Release date:2004-09-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
1X1S
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BU of 1x1s by Molmil
Crystal structure of M-Ras in complex with GppNHp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras
Authors:Ye, M, Shima, F, Muraoka, S, Liao, J, Okamoto, H, Yamamoto, M, Tamura, A, Yagi, N, Ueki, T, Kataoka, T.
Deposit date:2005-04-13
Release date:2005-07-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J.Biol.Chem., 280, 2005
1X3S
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BU of 1x3s by Molmil
Crystal structure of human Rab18 in complex with Gppnhp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-18
Authors:Kukimoto-Niino, M, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-10
Release date:2005-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Crystal structure of human Rab18 in complex with Gppnhp
To be Published
3KKQ
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BU of 3kkq by Molmil
Crystal structure of M-Ras P40D in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras
Authors:Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
1X1R
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BU of 1x1r by Molmil
Crystal structure of M-Ras in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras
Authors:Ye, M, Shima, F, Muraoka, S, Liao, J, Okamoto, H, Yamamoto, M, Tamura, A, Yagi, N, Ueki, T, Kataoka, T.
Deposit date:2005-04-12
Release date:2005-07-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J.Biol.Chem., 280, 2005
6O46
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BU of 6o46 by Molmil
Crystal structure of human KRAS P34R mutant in complex with GNP and Phosphate
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Bera, A.K, Westover, K.D.
Deposit date:2019-02-28
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R.
Birth Defects Res, 112, 2020
3KKM
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BU of 3kkm by Molmil
Crystal structure of H-Ras T35S in complex with GppNHp
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
3KKP
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BU of 3kkp by Molmil
Crystal structure of M-Ras P40D in complex with GppNHp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras
Authors:Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
1XCM
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BU of 1xcm by Molmil
Crystal structure of the GppNHp-bound H-Ras G60A mutant
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Transforming protein p21/H-Ras-1
Authors:Ford, B, Nassar, N.
Deposit date:2004-09-02
Release date:2005-05-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structure of the GppNHp-bound form of the RasG60A mutant
To be Published
3KKN
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BU of 3kkn by Molmil
Crystal structure of H-Ras T35S in complex with GppNHp
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
6OIM
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BU of 6oim by Molmil
Crystal Structure of human KRAS G12C covalently bound to AMG 510
Descriptor: AMG 510 (bound form), GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Mohr, C.
Deposit date:2019-04-09
Release date:2019-11-06
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.
Nature, 575, 2019
1XTQ
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BU of 1xtq by Molmil
Structure of small GTPase human Rheb in complex with GDP
Descriptor: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Yu, Y, Ding, J.
Deposit date:2004-10-24
Release date:2005-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
6O62
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BU of 6o62 by Molmil
Crystal structure of Sec4p, a Rab family GTPase from Candida albicans
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein SEC4
Authors:Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-03-05
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:To be published
To Be Published
3KKO
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BU of 3kko by Molmil
Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras, ...
Authors:Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
Deposit date:2009-11-06
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
1XJ0
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BU of 1xj0 by Molmil
Crystal Structure of the GDP-bound form of the RasG60A mutant
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein p21/H-Ras-1
Authors:Nassar, N, Skowronek, K.
Deposit date:2004-09-22
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of an intermediate for nucleotide exchange by Ras
To be Published
1XTS
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BU of 1xts by Molmil
Structure of small GTPase human Rheb in complex with GTP
Descriptor: GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Yu, Y, Ding, J.
Deposit date:2004-10-24
Release date:2005-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
3L8Y
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BU of 3l8y by Molmil
Complex of Ras with cyclen
Descriptor: 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
1XTR
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BU of 1xtr by Molmil
Structure of small GTPase human Rheb in complex with GppNHp
Descriptor: GLYCEROL, GTP-binding protein Rheb, MAGNESIUM ION, ...
Authors:Yu, Y, Ding, J.
Deposit date:2004-10-24
Release date:2005-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for the Unique Biological Function of Small GTPase RHEB
J.Biol.Chem., 280, 2005
3L8Z
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BU of 3l8z by Molmil
H-Ras wildtype new crystal form
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010
3LAW
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BU of 3law by Molmil
Structure of GTP-bound L129F mutant Rab7
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-7a
Authors:McCray, B.A, Skordalakes, E, Taylor, J.P.
Deposit date:2010-01-07
Release date:2010-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation.
Hum.Mol.Genet., 19, 2010
1YU9
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BU of 1yu9 by Molmil
GppNHp-Bound Rab4A
Descriptor: GTP-binding protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G.
Deposit date:2005-02-13
Release date:2005-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
3LBI
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BU of 3lbi by Molmil
Ras soaked in Magnesium Acetate and back soaked in Calcium Acetate
Descriptor: ACETATE ION, CALCIUM ION, GTPase HRas, ...
Authors:Holzapfel, G, Buhrman, G, Mattos, C.
Deposit date:2010-01-08
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Allosteric modulation of Ras positions Q61 for a direct role in catalysis.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LBN
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BU of 3lbn by Molmil
Ras soaked in Magnesium Acetate
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Holzapfel, G, Buhrman, G, Mattos, C.
Deposit date:2010-01-08
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.862 Å)
Cite:Allosteric modulation of Ras positions Q61 for a direct role in catalysis.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LO5
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BU of 3lo5 by Molmil
Crystal Structure of the dominant negative S17N mutant of Ras
Descriptor: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Nassar, N, Singh, K, Garcia-Diaz, M.
Deposit date:2010-02-03
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.568 Å)
Cite:Structure of the Dominant Negative S17N Mutant of Ras
Biochemistry, 49, 2010
3LBH
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BU of 3lbh by Molmil
Ras soaked in Calcium Acetate
Descriptor: ACETATE ION, CALCIUM ION, GTPase HRas, ...
Authors:Holzapfel, G, Buhrman, G, Mattos, C.
Deposit date:2010-01-08
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Allosteric modulation of Ras positions Q61 for a direct role in catalysis.
Proc.Natl.Acad.Sci.USA, 107, 2010

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