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3LIM
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BU of 3lim by Molmil
Crystal structure of the pore forming toxin frac from sea anemone actinia fragacea
Descriptor: Fragaceatoxin C, LAURYL DIMETHYLAMINE-N-OXIDE
Authors:Mechaly, A.E, Bellomio, A, Morante, K, Gonzalez-Manas, J.M, Guerin, D.M.A.
Deposit date:2010-01-25
Release date:2010-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins.
Structure, 19, 2011
6K2G
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BU of 6k2g by Molmil
Structure of FraE in the monomer state
Descriptor: FraE
Authors:Caaveiro, J.M.M, Morante, K, Tsumoto, K.
Deposit date:2019-05-14
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:The Isolation of New Pore-Forming Toxins from the Sea AnemoneActinia fragaceaProvides Insights into the Mechanisms of Actinoporin Evolution.
Toxins, 11, 2019
5GWF
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BU of 5gwf by Molmil
FraC with GlcNAc(6S) bound
Descriptor: 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, CHLORIDE ION, DELTA-actitoxin-Afr1a, ...
Authors:Caaveiro, J.M.M, Tsumoto, K.
Deposit date:2016-09-11
Release date:2017-06-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Haemolytic actinoporins interact with carbohydrates using their lipid-binding module
Philos. Trans. R. Soc. Lond., B, Biol. Sci., 372, 2017
4WDC
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BU of 4wdc by Molmil
High-resolution crystal structure of water-soluble FraC (mutation F16P)
Descriptor: Fragaceatoxin C
Authors:Caaveiro, J.M.M, Morante, K, Tsumoto, K.
Deposit date:2014-09-08
Release date:2015-03-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:A Pore-Forming Toxin Requires a Specific Residue for Its Activity in Membranes with Particular Physicochemical Properties
J.Biol.Chem., 290, 2015
5BPG
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BU of 5bpg by Molmil
Crystal structure of the water-soluble FraC purified starting from the trans-membrane pore
Descriptor: CHLORIDE ION, Fragaceatoxin C, GLYCEROL
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2015-05-28
Release date:2015-11-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Bidirectional Transformation of a Metamorphic Protein between the Water-Soluble and Transmembrane Native States
Biochemistry, 54, 2015
1TZQ
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BU of 1tzq by Molmil
Crystal structure of the equinatoxin II 8-69 double cysteine mutant
Descriptor: Equinatoxin II
Authors:Kristan, K, Podlesek, Z, Hojnik, V, Gutirrez-Aguirre, I, Guncar, G, Turk, D.A, Gonzalez-Maas, J.M, Lakey, J.H, Anderluh, G.
Deposit date:2004-07-11
Release date:2004-09-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich
J.Biol.Chem., 279, 2004
7EKZ
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BU of 7ekz by Molmil
Structural and functional insights into Hydra Actinoporin-Like Toxin 1 (HALT-1)
Descriptor: FORMIC ACID, GLYCEROL, HALT-1
Authors:Ker, D.S, Sha, X.H, Jonet, M.A, Hwang, J.S, Ng, C.L.
Deposit date:2021-04-07
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structural and functional analysis of Hydra Actinoporin-Like Toxin 1 (HALT-1).
Sci Rep, 11, 2021
7PUD
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BU of 7pud by Molmil
Bryoporin - actinoporin from moss Physcomitrium patens
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Bryoporin, SULFATE ION
Authors:Solinc, G, Anderluh, G, Podobnik, M.
Deposit date:2021-09-29
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Pore-forming moss protein bryoporin is structurally and mechanistically related to actinoporins from evolutionarily distant cnidarians.
J.Biol.Chem., 298, 2022
3ZWG
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BU of 3zwg by Molmil
Crystal structure of the pore-forming toxin FraC from Actinia fragacea (form 2)
Descriptor: FRAGACEATOXIN C
Authors:Mechaly, A.E, Bellomio, A, Morante, K, Gonzalez-Manas, J.M, Guerin, D.M.A.
Deposit date:2011-07-29
Release date:2012-07-04
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Pores of the Toxin Frac Assemble Into 2D Hexagonal Clusters in Both Crystal Structures and Model Membranes.
J.Struct.Biol., 180, 2012
3ZWJ
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BU of 3zwj by Molmil
CRYSTAL STRUCTURE OF THE PORE-FORMING TOXIN FRAC FROM ACTINIA FRAGACEA (Form 3)
Descriptor: FRAGACEATOXIN C
Authors:Mechaly, A.E, Bellomioa, A, Morantea, K, Gonzalez-Manas, J.M, Guerin, D.M.A.
Deposit date:2011-08-01
Release date:2012-07-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Pores of the Toxin Frac Assemble Into 2D Hexagonal Clusters in Both Crystal Structures and Model Membranes.
J.Struct.Biol., 180, 2012
1O72
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BU of 1o72 by Molmil
Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with phosphorylcholine
Descriptor: PHOSPHOCHOLINE, STICHOLYSIN II
Authors:Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A.
Deposit date:2002-10-23
Release date:2003-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation
Structure, 11, 2003
1O71
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BU of 1o71 by Molmil
Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with glycerol
Descriptor: GLYCEROL, STICHOLYSIN II
Authors:Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A.
Deposit date:2002-10-23
Release date:2003-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation
Structure, 11, 2003
3VWI
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BU of 3vwi by Molmil
High resolution crystal structure of FraC in the monomeric form
Descriptor: AMMONIUM ION, CHLORIDE ION, Fragaceatoxin C, ...
Authors:Tanaka, K, Morante, K, Caaveiro, J.M.M, Gonzalez-Manas, J.M, Tsumoto, K.
Deposit date:2012-08-23
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
3W9P
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BU of 3w9p by Molmil
Crystal structure of monomeric FraC (second crystal form)
Descriptor: Fragaceatoxin C
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2013-04-09
Release date:2014-04-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
1GWY
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BU of 1gwy by Molmil
Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II
Descriptor: STICHOLYSIN II, SULFATE ION
Authors:Mancheno, J.M, Martin-Benito, J, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A.
Deposit date:2002-03-26
Release date:2003-06-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation
Structure, 11, 2003
1IAZ
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BU of 1iaz by Molmil
EQUINATOXIN II
Descriptor: EQUINATOXIN II, SULFATE ION
Authors:Athanasiadis, A, Anderluh, G, Macek, P, Turk, D.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina.
Structure, 9, 2001
1KD6
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BU of 1kd6 by Molmil
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II
Descriptor: EQUINATOXIN II
Authors:Hinds, M.G, Zhang, W, Anderluh, G, Hansen, P.E, Norton, R.S.
Deposit date:2001-11-12
Release date:2002-02-13
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
J.Mol.Biol., 315, 2002
2KS4
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BU of 2ks4 by Molmil
NMR structure of the sea anemone actinoporin Sticholysin
Descriptor: Sticholysin-1
Authors:Castrillo, I, Santoro, J, Bruix, M.
Deposit date:2009-12-29
Release date:2010-09-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:1H, 13C, and 15N NMR assignments of the actinoporin Sticholysin I.
Biomol.Nmr Assign., 3, 2009
2L2B
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BU of 2l2b by Molmil
Structure of StnII-Y111N, a mutant of the sea anemone actinoporin Sticholysin II
Descriptor: Sticholysin-2
Authors:Pardo-Cea, M.A, Bruix, M, Santoro, J.
Deposit date:2010-08-16
Release date:2011-06-29
Last modified:2012-02-08
Method:SOLUTION NMR
Cite:Intrinsic local disorder and a network of charge-charge interactions are key to actinoporin membrane disruption and cytotoxicity.
Febs J., 278, 2011
2L38
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BU of 2l38 by Molmil
R29Q Sticholysin II mutant
Descriptor: Sticholysin-2
Authors:Castrillo, I, Alegre-Cebollada, J, Martinez-del-Pozo, A, Gavilanes, J, Bruix, M.
Deposit date:2010-09-10
Release date:2010-09-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of StnIIR29Q, a defective lipid binding mutant of the sea anemone actinoporin Sticholysin II
To be Published
4TSO
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BU of 4tso by Molmil
Crystal structure of FraC with DHPC bound (crystal form I)
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSP
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BU of 4tsp by Molmil
Crystal structure of FraC with DHPC bound (crystal form II)
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSL
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BU of 4tsl by Molmil
Crystal structure of FraC with POC bound (crystal form I)
Descriptor: ACETATE ION, FORMIC ACID, Fragaceatoxin C, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSY
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BU of 4tsy by Molmil
Crystal structure of FraC with lipids
Descriptor: 2-[[(E,2S,3R)-2-(hexanoylamino)-3-oxidanyl-dec-4-enoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, Fragaceatoxin C, HEPTANE-1,2,3-TRIOL, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
4TSN
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BU of 4tsn by Molmil
Crystal structure of FraC with POC bound (crystal form II)
Descriptor: ACETATE ION, Fragaceatoxin C, GLYCEROL, ...
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2014-06-19
Release date:2015-03-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015

 

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數據於2024-03-27公開中

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