7EVT
| Crystal structure of the N-terminal degron-truncated human glutamine synthetase | Descriptor: | Glutamine synthetase | Authors: | Chek, M.F, Kim, S.Y, Mori, T, Hakoshima, T. | Deposit date: | 2021-05-22 | Release date: | 2021-11-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of N-terminal degron-truncated human glutamine synthetase. Acta Crystallogr.,Sect.F, 77, 2021
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4XYC
| NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | Descriptor: | 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1 | Authors: | Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E. | Deposit date: | 2015-02-02 | Release date: | 2015-03-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 25, 2015
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5LDF
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4BAX
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3NG0
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7W85
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2WHI
| Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor and L-methionine-S- sulfoximine phosphate. | Descriptor: | 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... | Authors: | Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. | Deposit date: | 2009-05-05 | Release date: | 2009-09-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
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6PEW
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8DNU
| Human Brain Glutamine Synthetase | Descriptor: | Glutamine synthetase, MANGANESE (II) ION | Authors: | Tringides, M.L. | Deposit date: | 2022-07-11 | Release date: | 2022-11-16 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes. Life Sci Alliance, 6, 2023
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3FKY
| Crystal structure of the glutamine synthetase Gln1deltaN18 from the yeast Saccharomyces cerevisiae | Descriptor: | CITRATE ANION, Glutamine synthetase | Authors: | He, Y.X, Gui, L, Liu, Y.Z, Du, Y, Zhou, Y.Y, Li, P, Zhou, C.Z. | Deposit date: | 2008-12-18 | Release date: | 2009-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly Proteins, 76, 2009
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1HTQ
| Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis | Descriptor: | ADENOSINE MONOPHOSPHATE, CITRIC ACID, MANGANESE (II) ION, ... | Authors: | Gill, H.S, Pfluegl, G.M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2001-01-01 | Release date: | 2002-07-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation. Biochemistry, 41, 2002
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5ZLP
| Crystal structure of glutamine synthetase from helicobacter pylori | Descriptor: | (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Joo, H.K, Lee, J.Y. | Deposit date: | 2018-03-29 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Structural Analysis of Glutamine Synthetase from Helicobacter pylori. Sci Rep, 8, 2018
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8ECY
| cryoEM structure of bovine bestrophin-2 and glutamine synthetase complex | Descriptor: | Bestrophin, CALCIUM ION, CHLORIDE ION, ... | Authors: | Owji, A.P, Kittredge, A.K, Yang, T. | Deposit date: | 2022-09-02 | Release date: | 2022-11-02 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Bestrophin-2 and glutamine synthetase form a complex for glutamate release. Nature, 611, 2022
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4S0R
| Structure of GS-TnrA complex | Descriptor: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | Authors: | Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K. | Deposit date: | 2015-01-04 | Release date: | 2015-03-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. Genes Dev., 29, 2015
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4S17
| The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703 | Descriptor: | ACETATE ION, Glutamine synthetase, MAGNESIUM ION | Authors: | Cuff, M, Tan, K, Mack, J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-01-08 | Release date: | 2015-01-28 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of glutamine synthetase from Bifidobacterium adolescentis ATCC 15703 To be Published
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5ZLI
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2GLS
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8FBP
| Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation | Descriptor: | Glutamine synthetase | Authors: | Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2022-11-29 | Release date: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation To Be Published
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1LGR
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2LGS
| FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | Descriptor: | GLUTAMIC ACID, GLUTAMINE SYNTHETASE, MANGANESE (II) ION | Authors: | Liaw, S.-H, Eisenberg, D. | Deposit date: | 1994-08-05 | Release date: | 1994-11-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine. Proc.Natl.Acad.Sci.USA, 90, 1993
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4LNN
| B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of apo form of GS | Descriptor: | Glutamine synthetase, MAGNESIUM ION, SULFATE ION | Authors: | Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. | Deposit date: | 2013-07-11 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
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4LNO
| B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: form two of GS-1 | Descriptor: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION | Authors: | Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. | Deposit date: | 2013-07-11 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
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4LNI
| B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... | Authors: | Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. | Deposit date: | 2013-07-11 | Release date: | 2013-11-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5793 Å) | Cite: | Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
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4IS4
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3ZXR
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