Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2D9D
DownloadVisualize
BU of 2d9d by Molmil
Solution structure of the BAG domain (275-350) of BAG-family molecular chaperone regulator-5
Descriptor: BAG family molecular chaperone regulator 5
Authors:Hatta, R, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-09
Release date:2006-12-09
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
1T7S
DownloadVisualize
BU of 1t7s by Molmil
Structural Genomics of Caenorhabditis elegans: Structure of BAG-1 protein
Descriptor: BAG-1 cochaperone
Authors:Symersky, J, Zhang, Y, Schormann, N, Li, S, Bunzel, R, Pruett, P, Luan, C.-H, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-05-10
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural genomics of Caenorhabditis elegans: structure of the BAG domain.
Acta Crystallogr.,Sect.D, 60, 2004
1UGO
DownloadVisualize
BU of 1ugo by Molmil
Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5
Descriptor: Bcl2-associated athanogene 5
Authors:Endoh, H, Hayashi, F, Seimiya, K, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-17
Release date:2004-08-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
1UK5
DownloadVisualize
BU of 1uk5 by Molmil
Solution structure of the Murine BAG domain of Bcl2-associated athanogene 3
Descriptor: BAG-family molecular chaperone regulator-3
Authors:Hatta, R, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-08-19
Release date:2004-02-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
1I6Z
DownloadVisualize
BU of 1i6z by Molmil
BAG DOMAIN OF BAG1 COCHAPERONE
Descriptor: BAG-FAMILY MOLECULAR CHAPERONE REGULATOR-1
Authors:Briknarova, K, Takayama, S, Brive, L, Havert, M.L, Knee, D.A, Velasco, J, Homma, S, Cabezas, E, Stuart, J, Hoyt, D.W, Satterthwait, A.C, Llinas, M, Reed, J.C, Ely, K.R.
Deposit date:2001-03-06
Release date:2001-09-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein.
Nat.Struct.Biol., 8, 2001
1M62
DownloadVisualize
BU of 1m62 by Molmil
Solution structure of the BAG domain from BAG4/SODD
Descriptor: BAG-family molecular chaperone regulator-4
Authors:Briknarova, K, Takayama, S, Homma, S, Baker, K, Cabezas, E, Hoyt, D.W, Li, Z, Satterthwait, A.C, Ely, K.R.
Deposit date:2002-07-11
Release date:2002-07-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:BAG4/SODD protein contains a short BAG domain.
J.Biol.Chem., 277, 2002
1M7K
DownloadVisualize
BU of 1m7k by Molmil
Solution Structure of the SODD BAG Domain
Descriptor: Silencer of Death Domains
Authors:Brockmann, C, Leitner, D, Labudde, D, Diehl, A, Sievert, V, Buessow, K, Oschkinat, H.
Deposit date:2002-07-22
Release date:2002-08-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The solution structure of the SODD BAG domain reveals additional electrostatic interactions in the HSP70 complexes of SODD subfamily BAG domains
Febs Lett., 558, 2004
4HWF
DownloadVisualize
BU of 4hwf by Molmil
Crystal structure of ATBAG3
Descriptor: BAG family molecular chaperone regulator 3, SULFATE ION
Authors:Shen, Y, Fang, S.
Deposit date:2012-11-07
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thaliana.
Acta Crystallogr.,Sect.D, 69, 2013
4HWC
DownloadVisualize
BU of 4hwc by Molmil
Structure of ATBAG1
Descriptor: BAG family molecular chaperone regulator 1, CHLORIDE ION
Authors:Shen, Y, Fang, S.
Deposit date:2012-11-07
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thaliana.
Acta Crystallogr.,Sect.D, 69, 2013
4HWH
DownloadVisualize
BU of 4hwh by Molmil
Crystal structure of ATBAG4
Descriptor: ACETATE ION, BAG family molecular chaperone regulator 4, GLYCEROL, ...
Authors:Shen, Y, Fang, S.
Deposit date:2012-11-07
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Structural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thaliana.
Acta Crystallogr.,Sect.D, 69, 2013
4HWD
DownloadVisualize
BU of 4hwd by Molmil
Crystal structure of ATBAG2
Descriptor: BAG family molecular chaperone regulator 2
Authors:Shen, Y, Fang, S.
Deposit date:2012-11-07
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.312 Å)
Cite:Structural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thaliana.
Acta Crystallogr.,Sect.D, 69, 2013
3M3Z
DownloadVisualize
BU of 3m3z by Molmil
Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor
Descriptor: 5'-O-(2-amino-2-oxoethyl)-8-(methylamino)adenosine, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein
Authors:Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S.
Deposit date:2010-03-10
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity.
J.Med.Chem., 54, 2011
5AQS
DownloadVisualize
BU of 5aqs by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
Descriptor: BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, GLYCEROL, HEAT SHOCK COGNATE 71 KDA PROTEIN, ...
Authors:Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
Deposit date:2015-09-22
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
3A8Y
DownloadVisualize
BU of 3a8y by Molmil
Crystal structure of the complex between the BAG5 BD5 and Hsp70 NBD
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 5, Heat shock 70 kDa protein 1
Authors:Arakawa, A, Handa, N, Ohsawa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2009-10-13
Release date:2010-03-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
3FZK
DownloadVisualize
BU of 3fzk by Molmil
Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors
Descriptor: (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, ...
Authors:Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E.
Deposit date:2009-01-26
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
J.Med.Chem., 52, 2009
1HX1
DownloadVisualize
BU of 1hx1 by Molmil
CRYSTAL STRUCTURE OF A BAG DOMAIN IN COMPLEX WITH THE HSC70 ATPASE DOMAIN
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, Heat shock 70 kDa protein 8
Authors:Sondermann, H, Scheufler, C, Moarefi, I.
Deposit date:2001-01-11
Release date:2001-03-07
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors.
Science, 291, 2001
3FZL
DownloadVisualize
BU of 3fzl by Molmil
Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, BAG family molecular chaperone regulator 1, ...
Authors:Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E.
Deposit date:2009-01-26
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
J.Med.Chem., 52, 2009
3FZM
DownloadVisualize
BU of 3fzm by Molmil
Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors
Descriptor: 4-[[(2R,3S,4R,5R)-5-[6-amino-8-(quinolin-6-ylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitri le, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein
Authors:Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E.
Deposit date:2009-01-26
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
J.Med.Chem., 52, 2009
3FZH
DownloadVisualize
BU of 3fzh by Molmil
Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors
Descriptor: (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein
Authors:Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E.
Deposit date:2009-01-26
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
J.Med.Chem., 52, 2009
3FZF
DownloadVisualize
BU of 3fzf by Molmil
Crystal Structure of Hsc70/Bag1 in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein
Authors:Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E.
Deposit date:2009-01-26
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
J.Med.Chem., 52, 2009
4HWI
DownloadVisualize
BU of 4hwi by Molmil
Crystal structure of ATBAG1 in complex with HSP70
Descriptor: BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein
Authors:Shen, Y, Fang, S.
Deposit date:2012-11-07
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.273 Å)
Cite:Structural insight into plant programmed cell death mediated by BAG proteins in Arabidopsis thaliana.
Acta Crystallogr.,Sect.D, 69, 2013
3LDQ
DownloadVisualize
BU of 3ldq by Molmil
Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor
Descriptor: 8-[(quinolin-2-ylmethyl)amino]adenosine, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein
Authors:Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S.
Deposit date:2010-01-13
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity.
J.Med.Chem., 54, 2011
5AQT
DownloadVisualize
BU of 5aqt by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
Descriptor: (1S,2R,3R,5R)-3-(hydroxymethyl)-5-(quinazolin-4-ylamino)cyclopentane-1,2-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ...
Authors:Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
Deposit date:2015-09-22
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
5AQM
DownloadVisualize
BU of 5aqm by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, GLYCEROL, ...
Authors:Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
Deposit date:2015-09-22
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
5AQH
DownloadVisualize
BU of 5aqh by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
Descriptor: 5-methyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, DIMETHYL SULFOXIDE, ...
Authors:Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
Deposit date:2015-09-22
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016

 

12>

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon